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Novel application of nauclea officinalis extract

A technology of extract and bile wood, applied in the field of medicine, can solve problems such as discomfort in use, prone to dryness, peeling, irritation, and skin irritation, and achieve the effects of avoiding side effects, high development prospects, and inhibiting growth.

Inactive Publication Date: 2019-01-04
戴姝君
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, these products are either prone to drug resistance, or are irritating to the skin, uncomfortable to use, and prone to reactions such as dryness, peeling, and irritation. Therefore, there is an urgent need to develop a topical drug with good curative effect and mild effect.

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0024] Embodiment 1, the preparation method of leaf extract

[0025] Take 100 g of the leaves of P. chinensis, add 15 times the mass of 85% ethanol, heat and reflux extraction for 3 times, each time for 30 minutes, take the extract, concentrate under reduced pressure to obtain the extract, and obtain the leaf extract of P. chinensis.

Embodiment 2

[0026] The preparation method of embodiment 2, birch branch extract

[0027] Take 100 g of dried twigs of dandelion, crush them, add 15 times the mass of 80% ethanol, heat and reflux for extraction 3 times, each time for 30 minutes, take the extract, concentrate under reduced pressure to obtain the extract of twigs of twigs.

Embodiment 3

[0028] The preparation method of embodiment 3, gallwood bark extract

[0029] Take 100 g of dry bark of P. japonica, crush it, add 15 times the mass of 75% ethanol, heat and reflux for extraction 3 times, each time for 30 minutes, take the extract, concentrate it under reduced pressure to extract, and then obtain the bark of P. chinensis extract.

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PUM

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Abstract

The invention belongs to the field of medicines, and discloses novel application of a nauclea officinalis extract, in particular application of the nauclea officinalis extract to preparation of a propionibacterium acne inhibitor. Experiments show that the nauclea officinalis extract has propionibacterium acne inhibiting activity and can inhibit growth of propionibacterium acnes, so that the nauclea officinalis extract can be applied to preparation of the propionibacterium acne inhibitor and preparation of medicines for treating the acnes and cosmetics for improving the acnes and has a relatively high application value and a relatively high development prospect; in addition, the nauclea officinalis extract uses a natural material, so that the side effects caused by the conventional antibiotic products to a human body can be avoided.

Description

technical field [0001] The invention belongs to the field of medicine, and in particular relates to the new application of the extract of the eucalyptus, in particular to the application of the extract of the eucalyptus in preparing inhibitors of Propionibacterium acnes. Background technique [0002] Acne, also known as acne, is a chronic inflammatory skin disease of the pilosebaceous unit. Its occurrence is closely related to factors such as excessive sebum secretion, pilosebaceous duct blockage, bacterial infection, and inflammatory response. After entering puberty, the level of androgen in the human body, especially testosterone, increases rapidly. Testosterone is converted into dihydrotestosterone through the action of 5-α reductase in the skin, and the latter binds to the androgen receptor of sebocytes to play a role. Elevated androgen levels promote the development of sebaceous glands and produce large amounts of sebum. Sebum is mainly composed of squalene, wax esters...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/74A61K9/06A61P31/04A61P17/10A61K8/9789A61Q19/00A61K135/00A61K129/00A61K127/00
CPCA61K9/0014A61K9/06A61K36/74A61K2236/333A61K2236/51A61Q19/00A61K8/9789A61P17/10A61P31/04
Inventor 戴姝君
Owner 戴姝君
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