Composition for promoting fermentation of vitamin B12 and application of composition

Abstract

The invention relates to the field of preparation of vitamin B12, in particular to a composition for promoting fermentation of vitamin B12 and application of the composition. The composition for promoting fermentation of the vitamin B12 is mainly prepared from the following raw materials in parts by mass: 1-1.55 percent of a composite precursor, 2-10 percent of composite amino organic acid, 30-40percent of composite thallus hydrolysate and 50-70 percent of tap water. For the composition for promoting fermentation of the vitamin B12 and the application of the composition, the problems of instable fermentation and low yield are solved, the fermentation yield is greatly increased, and the purposes of reduction in energy consumption and clean production are realized; when the composition forpromoting fermentation of the vitamin B12 is applied to fermentation process of the vitamin B12, the fermentation-promoting composition is continuously supplemented in the fermentation process, so that supply of various nutritional ingredients in the fermentation process and the fermentation effect are ensured, and the fermentation yield of the vitamin B12 is effectively increased.

Description

technical field [0001] The invention relates to the field of preparation of vitamin B12, in particular to a composition for promoting the fermentation of vitamin B12 and an application thereof. Background technique [0002] Vitamin B12 is a cobalamin compound, which is mainly used clinically to treat pernicious anemia, and is also used to treat various nervous system diseases and certain liver diseases. [0003] At present, vitamin B12 is mainly obtained through aerobic fermentation by Pseudomonas denitrification bacteria. The main components of the fermentation medium include organic carbon sources, organic nitrogen sources, betaine, a small amount of inorganic salts, and the like. Among them, the trace element nutritional factors attached to organic matter are indispensable factors for normal function and metabolic activities. As cofactors, they participate in the regulation of many microbial metabolisms and are a key link in the regulation of microbial metabolism. Differ...

AI Technical Summary

Problems solved by technology

However, in microbial fermentation production, the content of nutritional factors in organic cultures produced by different manufacturers, at different times, and with different processes is uneven, which seriously affects the control of the fermentation process and the fermentation effect.

[0004] In addition, the existing vitamin B12 production process will produce a large amount of bacterial protein. These bacterial proteins have low added value and have always been dried and sold as feed. During the production process, wet bacterial cells are not easy to store and cause mildew. It has caused great waste and polluted the environment, and the drying of the bacteria is a large energy-consuming household, which is not conducive to the national energy-saving and emission-reduction policy.