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A kind of nonallergic rubber plaster plaster and preparation method thereof

A technology for rubber plasters and plasters, which is applied to medical preparations with no active ingredients, medical preparations containing active ingredients, and pharmaceutical formulas, etc. It can solve problems such as poor air permeability, variable quality of plasters, and long medication cycles. problem, to achieve the effect of improving the therapeutic effect, high transdermal absorption rate, and high bonding performance

Active Publication Date: 2022-04-19
INNER MONGOLIA HORQIN PHARMA CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] When the usual external plasters are applied to the skin, especially to the joints, such as knees, elbows and other vigorously active parts, there will be problems such as weak application, shedding and poor air permeability, which will affect the curative effect
For example, the existing plasters have the following deficiencies: 1. Some plasters are poorly targeted and have unsatisfactory drug effects; 2. The transdermal absorption rate of the plasters is low, slow to take effect, and the drug cycle is long; 3. The active ingredients in the plasters are volatile and cause The drug effect is reduced; 4. The thickness of the plaster is not enough, and the adhesion is poor, so that the plaster is easy to be damp; 5. The ingredients are unevenly dispersed in the plaster, resulting in different quality of the plaster; 5. The air permeability of the plaster is poor, and the air permeability is not good , easy to cause skin itching and aggravate skin allergies
Equally the plaster disclosed by this invention does not relate to the transdermal problem and the viscosity problem of the plaster

Method used

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  • A kind of nonallergic rubber plaster plaster and preparation method thereof
  • A kind of nonallergic rubber plaster plaster and preparation method thereof
  • A kind of nonallergic rubber plaster plaster and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0046] Embodiment 1 a kind of nonallergic rubber plaster plaster

[0047] Comprising the following medicinal materials in parts by weight:

[0048]

[0049] Preparation method: comprising the following steps:

[0050] (1) Pulverize the Tugucao, Chuanfuzi, Baifuzi, Zhicaowu, Zhichuanwu, Araceae and Millae Spatholobus to 850 μm ± 29 μm, soak in vinegar for 18 hours, then decoct and extract 3 times, The amount of vinegar added during decoction is 2cm higher than the surface of the medicinal material, the decoction temperature is 100°C, the time is 3 hours for the first decoction, 2 hours for the second time, and 2 hours for the third time. 1 hour, filter, and combine the decoction to obtain the extract;

[0051] (2) Concentrate the extract obtained in step (1) to a relative density of 1.3, use 80% by volume and 3 times the total amount of medicinal materials for alcohol precipitation, recover ethanol under reduced pressure, and then concentrate again When the relative densi...

Embodiment 2

[0055] Embodiment 2 A kind of nonallergic rubber plaster plaster

[0056] Comprising the following medicinal materials in parts by weight:

[0057]

[0058] Preparation method: comprising the following steps:

[0059] (1) Pulverize the Tugucao, Chuanfuzi, Baifuzi, Zhicaowu, Zhichuanwu, Araceae and Millae Spatholobus to 850 μm ± 29 μm, soak in vinegar for 18 hours, then decoct and extract 3 times, The amount of vinegar added during decoction is 3cm higher than the surface of the medicinal material, the decoction temperature is 110°C, the time is 3 hours for the first decoction, 2 hours for the second time, and 2 hours for the third time 1 hour, filter, and combine the decoction to obtain the extract;

[0060] (2) Concentrate the extract obtained in step (1) to a relative density of 1.2, use 80% by volume and 3 times the total amount of medicinal materials for alcohol precipitation, recover the ethanol under reduced pressure, and concentrate again When the relative density...

Embodiment 3

[0064] Embodiment 3 a kind of nonallergic rubber plaster plaster

[0065] Comprising the following medicinal materials in parts by weight:

[0066]

[0067]

[0068] Preparation method: comprising the following steps:

[0069] (1) Pulverize the Tugucao, Chuanfuzi, Baifuzi, Zhicaowu, Zhichuanwu, Araceae and Millae Spatholobus to 850 μm ± 29 μm, soak in vinegar for 18 hours, then decoct and extract 3 times, The amount of vinegar added during decoction is 5cm higher than the surface of the medicinal material, the decoction temperature is 120°C, the time is 3 hours for the first decoction, 2 hours for the second time, and 2 hours for the third time. 1 hour, filter, and combine the decoction to obtain the extract;

[0070] (2) Concentrate the extract obtained in step (1) to a relative density of 1.1, use 80% by volume of ethanol that is twice the total amount of medicinal materials to carry out alcohol precipitation, recover ethanol under reduced pressure, and then concentr...

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Abstract

The invention provides a non-allergic rubber plaster and a preparation method thereof, belonging to the technical field of plaster preparations. The rubber plaster plaster disclosed by the present invention comprises the following medicinal materials in parts by weight: 1-7 parts of Speranthus fragrans, 5-14 parts of Radix Aconiti Radix, 5-13 parts of Radix Aconiti Radix, 5-13 parts of Radix Aconitum, 5 parts of Radix Aconitum ‑13 parts, 5‑15 parts of Aracea, 5‑13 parts of Millet, 2‑10 parts of menthol, 1‑8 parts of camphor and 2‑10 parts of borneol. The non-allergic rubber plaster plaster provided by the invention uses polymer artificial rubber instead of natural rubber, which effectively solves the problem of allergies. The obtained rubber plaster plaster has a high transdermal absorption rate, can make the active ingredients of the medicine absorb faster, improve the therapeutic effect, and simultaneously make the plaster have high bonding performance and high stability.

Description

technical field [0001] The invention belongs to the technical field of plaster preparations, and in particular relates to a non-allergic rubber plaster and a preparation method thereof. Background technique [0002] Plaster therapy, which works through the skin, is one of the commonly used external treatment methods in TCM clinics. TCM external plaster uses the principle of meridian distribution of traditional Chinese medicine to fully mobilize the effectiveness of the coordination of drugs to form a compound of multi-flavored drugs. To bring into play the good effect of medicine. Because the plaster is directly applied on the body surface, it penetrates into the skin and transmits the meridians and internal organs to play the functions of regulating qi and blood, dredging the meridians, expelling cold and damp, and reducing swelling and pain. [0003] External plaster Colloidal material coated on elastic cloth or non-elastic cloth to make external plaster tape, and a finis...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K9/70A61K36/8884A61K47/32A61K47/44A61K31/045A61K31/125
Inventor 伏莹任志福高文福
Owner INNER MONGOLIA HORQIN PHARMA CO LTD
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