87 results about "Skin itching" patented technology

The invention discloses an application of betulinic acid 28-O-beta-D-glucoside (BA-6 for short) in preparation of a medicine for preventing and treating skin inflammation. The problems that an existing medicine for treating dermatitis is limited in curative effect, slow in effect taking, multiple in side effect, high in long-term use risk, large in individual difference, high in treatment cost, likely to cause immunoreaction and the like are solved. The invention discloses application of BA-6 in prevention and treatment of atopic dermatitis, contact dermatitis, eczema, rash, psoriasis, lupus erythematosus, papule squamous skin disease, pityriasis rosea, seborrheic dermatitis, pemphigus, celestial abscess, acne, tinea corporis, impetigo, SAPHO syndrome, hidradenitis suppurativa, dermatitis caused by drugs, lichen planus, pityriasis rubra pilaris, vitiligo, prurigo nodularis, dermatitis caused by drugs, and the like for the first time. The traditional Chinese medicine composition can be used for treating skin diseases, systemic sclerosis, hidradenitis suppurativa, granulomatous skin diseases, vitiligo, dermatomyositis, chronic skin itch and alopecia areata, and has the technical progress of obviously improving skin erythema, papule, edema, scale, moss and ulceration symptoms.

Provided are a use of epicatechin or a legume extract containing epicatechin for preparing a composition for tranquilizing skin, and a skin itch treatment method comprising a step of applying a cosmetic composition to the skin of an individual causing itch, the cosmetic composition being the composition for tranquilizing skin.

The invention belongs to the technical field of microorganisms, and particularly relates to an extracellular vesicle of phytobacterium plantarum and application of the extracellular vesicle. Specifically, the plant lactobacillus extracellular vesicles can promote HaCaT cells to generate ceramide, up-regulate expression of key genes in a skin ceramide synthesis route and recover a skin barrier; the expression of proinflammatory factors in a cell inflammation model can be reduced, and a relatively good anti-inflammatory effect is achieved. A mouse skin injury model verifies that the EVs has good skin infiltration capacity and can remarkably reduce the skin injury score, relieve skin itch, improve the skin water content and reduce expression of proinflammatory factors in skin tissue and expression of pruritus-related cell factors.

The invention discloses a soothing composition for relieving itching of a body and application of the soothing composition, and relates to the technical field of cosmetics. The invention discloses a soothing and itching relieving composition, which is prepared from the following ingredients in parts by weight: 0.1 to 0.5 part of phoenix dactylifera seeds, 1 to 5 parts of hyperforin perforatum flower extracts, 1 to 10 parts of Brazil nectarine fruit oil and 0.01 to 0.2 part of L-homoserine. Through cooperation of the phoenix dactylifera seeds, the hyperforin perforatum flower extract, the Brazilian nectarine fruit oil and the L-homoserine, on one hand, when the temperature changes and nursing is improper, sensitive skin can be helped to be calm and relaxed, and the resistance of the skin to external environment influence is enhanced; on the other hand, the composition can synergistically moisturize, relieve and reduce skin sensitivity and prevent skin itch and dryness.

The present invention relates to a method for stabilizing ceramide and to a cosmetic composition containing stabilized ceramide and, more specifically, to a method for homogenizing and stabilizing ceramide by self-assembling the ceramide together with β-sitosterol, resveratrol, and allantoin which are other physiologically active substances using a microfluidic chip and a high pressure homogenizer, and to a technique for using ceramide and nanoparticles containing β-sitosterol, resveratrol, and allantoin, which are produced by means of the stabilizing method, as a cosmetic material for skin moisturizing, anti-oxidation, skin inflammation relief, skin barrier enhancement, and skin itching relief.

The present invention relates to a composition for improving skin, which comprises beta-sitosterol and betulin and, in the case of the composition, reduces dermatoneuropathic stimulation-inducing factors, increases the expression of moisturizing-related factors, increases skin absorbance, improves skin penetration, inhibits mast cell activity, and improves skin quality. Thus, it has been confirmed that the composition has excellent skin-calming and skin-irritation-relieving effects, and thus can be usefully used in skin-improving cosmetics, pharmaceuticals, and the like.

The invention provides an external composition for improving the sub-health state of people in a high-glucose lifestyle and application of the external composition, and belongs to the technical field of biological agents. The composition provided by the invention is prepared from the following components: caffeine silanol C, a radix sophorae flavescentis extract, a lotus leaf extract, a corn poppy extract, a bitter gourd extract, soy isoflavone, beta-glucan, a tea leaf extract, an apple extract, resveratrol, a pueraria mirifica extract, a propolis extract, an angelica sinensis root extract, a radix ophiopogonis extract and a rhizoma anemarrhenae root extract. The composition is prepared from a fructus gardeniae extract, a Thermus thermophilus fermentation product, oligopeptide-1 and carnosine. The composition provided by the invention can be prepared into an external preparation, is suitable for people in the high-glucose lifestyle, has the technical effects of improving the sub-health states of the people in the high-glucose lifestyle, such as weakness, skin itch, dark skin color, thirst, frequent urination and the like, and improves the life quality of the people in the high-glucose lifestyle.

The invention provides an oral medicine formula for treating psoriasis, and relates to the field of traditional Chinese medicine formulas. The oral medicine for treating psoriasis is prepared from the following raw materials by weight: 10 g of astragalus membranaceus, 50 g of rhizoma smilacis glabrae, 10 g of salvia miltiorrhiza, 10 g of cassia twig, 10 g of cicada slough, 10 g of ligusticum wallichii, 30 g of angelica sinensis and 10 g of honey-fried licorice root. Salvia miltiorrhiza, ligusticum wallichii, angelica sinensis and other medicines have the effects of promoting blood circulation to remove blood stasis, can improve the blood circulation state of skin and promote repair of skin lesions, and have a certain curative effect on blood stasis type psoriasis patients; cassia twig and cicada slough have the effects of dispelling wind and arresting itching, can relieve the symptom of skin itch, and improve the life quality of patients; astragalus membranaceus, angelica sinensis and honey-fried licorice root have the effects of reinforcing qi and nourishing blood, can improve the overall physique of a patient, enhance the immunity of the body and contribute to disease recovery, the clinical effective rate reaches 70% or above, one treatment course lasts for three months, and the cure rate can reach 40% or above.

The invention discloses a traditional Chinese medicine composition for moistening skin and relieving itching. The traditional Chinese medicine composition for moistening skin and relieving itching is prepared from fresh radix rehmanniae, fresh herba portulacae, peach kernels, almonds, radix angelicae sinensis, rhizoma bletillae, cortex moutan, cortex phellodendri, cortex dictamni, cortex lycii radicis, folium artemisiae argyi and raw liquorice. The invention further discloses external cream based on the traditional Chinese medicine skin moistening and itching relieving composition and a preparation method of the cream. The invention solves the problem of lack of an external traditional Chinese medicine cream preparation for skin itch and dryness caused by blood heat, blood deficiency, blood dryness and the like in the prior art.

The present application belongs to the field of daily cosmetics, and particularly relates to a toner composition containing irises root extract and a preparation method thereof, which comprises the following components calculated by weight percentage: 1.0-5.0% of irises root extract; 0.05-1.0% of menthol; 1.0-10.0% of humectant; 0.01-1.0% of antioxidant; 0.005-0.2% of chelating agent; 0.01-1.0% of preservative; 0.01-3% of essence; 0.01-0.4% of neutralizing agent; and the balance of deionized water. The synergistic effect of irises root extract and menthol can improve the effects of the composition on skin itching, repair and calming, enhance the function of the skin, thereby reducing the possibility of skin tightness, redness and inflammation, and helping the skin to maintain a healthy state.

The present application relates to a preparation method of high-efficiency stable mulberry root extract containing oxyresveratrol and its application in relieving skin itching, and belongs to the technical field of cosmetics. The preparation method of the mulberry root extract containing oxyresveratrol comprises the following steps: drying and crushing the root of a mulberry tree, adding the crushed root into an aqueous solution of a eutectic solvent to perform ultrasonic extraction, centrifuging the product to obtain the mulberry root extract containing oxyresveratrol. The present application is based on a green solvent system composed of betaine and 1,3-propanediol / ethyl lactate, and combines with mild ultrasonic conditions to realize the efficient extraction of oxyresveratrol from the mulberry root, so that the extraction rate is improved and the risk of high-temperature oxidation is avoided. Moreover, the obtained extract can not only long-acting inhibit the itch receptor MRGPX1, but also is suitable for sensitive skin due to the removal of irritating components, and has high efficiency and biocompatibility, thereby breaking through the environmental pollution and technical bottleneck of the traditional method and having a wide market application prospect.

The invention relates to the technical field of medicines, in particular to skin antibacterial transdermal liquid and a preparation method thereof. The traditional Chinese medicine composition is prepared by mixing the following raw materials in percentage by weight: 0.1%-0.4% of radix euphorbiae lantu, 0.25%-0.75% of rhizoma smilacis glabrae, 0.15%-0.55% of honeysuckle flower, 0.08%-0.38% of radix salviae miltiorrhizae, 0.2%-0.8% of flos chrysanthemi indici, 0.05%-0.55% of spina gleditsiae, 0.05%-0.45% of typhonium giganteum, 3%-8% of borneol, 0.25%-0.6% of radix sophorae flavescentis, 0.2%-0.65% of fructus cnidii, 0.15%-0.45% of fructus kochiae, 0.01%-0.45% of radix stemonae and 0.02%-0.55% of chlorhexidine acetate. The skin antibacterial transdermal liquid has the beneficial effects that through the synergistic interaction of various natural traditional Chinese medicine components and the combination of a modern extraction process, effective components are fully reserved, the skin antibacterial transdermal liquid has a remarkable inhibition effect on various skin pathogenic bacteria such as staphylococcus aureus, escherichia coli and candida albicans, and the antibacterial rate can reach 90% or above; meanwhile, the traditional Chinese medicine is used for improving skin microcirculation, and penetration promoting components such as borneol are used, so that the medicine can quickly penetrate through the skin cuticle and penetrate into the skin tissue to exert the medicine effect, the symptoms such as skin itch and inflammation are effectively relieved, the preparation process is relatively simple, and industrial production is easy.

The invention discloses a traditional Chinese medicine composition for treating diabetic skin itch and a preparation method thereof, and belongs to the technical field of traditional Chinese medicines. The composition is prepared from angelica sinensis, astragalus membranaceus, radix paeoniae rubra, cortex dictamni, rehmannia, ligusticum wallichii, scalded peach kernels, safflower carthamus, fried tribulus terrestris, divaricate saposhnikovia roots and cicada slough according to a specific weight ratio. On the basis of a classic famous formula of the Chinese angelica potion, the Chinese angelica potion is innovatively prepared aiming at the core pathogenesis of qi deficiency, blood stasis, damp-heat and wind-dryness of diabetic skin itch. The radix paeoniae rubra and the radix paeoniae alba are used for enhancing the effects of cooling blood and dissipating blood stasis; peach kernel and safflower are added to strengthen blood circulation activation and collateral dredging; cortex dictamni is added to enhance dampness eliminating and detoxification; cicada slough and herba schizonepetae are used for enhancing wind dispelling and heat clearing, and the nature is Polygonum multiflorum and liquorice are removed, so that the safety is improved. The whole formula has the effects of tonifying qi, promoting blood circulation, eliminating dampness, detoxifying, dispelling wind and moistening dryness. The invention also provides a preparation method of the composition. The composition can be used for preparing medicines for treating skin diseases such as diabetic skin itch and eczema, and is remarkable in curative effect and high in safety.

The utility model relates to the technical field of shoulder joint orthosis, and discloses a shoulder joint orthosis with good air permeability, which comprises a side plate, a first support plate is movably hinged to the left side of the top end of the side plate, and a second support plate is arranged on the left side of the first support plate. According to the shoulder joint orthosis with the good air permeability, the protection pad, the waist protection pad and the second ventilation holes are arranged, lyocell fibers are natural plant fibers and have the advantages of being natural in gloss, smooth in hand feeling, high in strength, good in moisture permeability and air permeability and the like, and the second ventilation holes and the first ventilation holes can further improve the air permeability of the waist protection pad and other assemblies; the problems of skin itch, skin eczema, chronic dermatitis and the like caused by air tightness after wearing are prevented, so that the air permeability of the shoulder joint orthosis is improved, a patient can be protected, the comfort of the patient during use is improved, and the problems that the air permeability of the shoulder joint orthosis is poor, and skin itch of the patient is likely to be caused are solved.

The utility model relates to the technical field of medical instruments, in particular to a disposable electrocardio-electrode which comprises a backing, an adhesive layer arranged below the backing, a conductive electrode arranged between the backing and the adhesive layer, and a copper buckle connected to the top end of the conductive electrode in a sleeved mode. A conductive adhesive layer is arranged below the conductive electrode, and release paper is arranged below the backing, the adhesive layer and the conductive adhesive layer; a ventilation mechanism is arranged on the inner side of the back lining, and a stabilizing mechanism is arranged among the back lining, the adhesive layer and the conductive electrode. Due to the existence of the breathable layer, the first breathable groove and the second breathable groove, the breathability of the electrode is improved, sweat on the surface of skin can be discharged in time, the possibility that the skin is in a humid environment for a long time is reduced, and a user does not feel uncomfortable due to the fact that the skin below the electrode is too humid during 24-hour dynamic electrocardiogram monitoring. The occurrence rate of skin problems such as skin itch and red swelling is reduced.

The present invention relates to a cosmetic material composition for improving skin condition, the composition comprising a beta vulgaris subsp. vulgaris Altissima Group root extract and, more specifically, to a cosmetic composition for enhancing skin moisturization, improving skin elasticity, and alleviating skin itching, the composition comprising a beta vulgaris subsp. vulgaris Altissima Group root extract. The cosmetic material composition comprising a beta vulgaris subsp. vulgaris Altissima Group root extract according to the present invention can be variously formulated into a toner, a lotion, a cream, an ointment, or the like.

The invention discloses a plant-based efficient skin anti-allergy soothing repair agent as well as a preparation method and application thereof. In the traditional Chinese medicine composition, various plant extracts such as the cortex dictamni extract, the fructus kochiae extract, the radix scutellariae extract, the dandelion extract and the honeysuckle flower extract have a synergistic effect, so that the traditional Chinese medicine composition has various effects of resisting allergy, bacteria, inflammation and viruses and the like. The components can effectively inhibit mast cell functions, reduce release of inflammatory mediators and relieve allergic symptoms, such as pruritus, redness and swelling, stabbing pain and the like. Meanwhile, soothing and repairing components in the formula, such as a chamomile extract, an aloe extract and a liquorice root extract, can effectively relieve symptoms such as skin itch, redness and swelling and the like, promote skin repair, help repair damaged skin barriers, enhance skin resistance and reduce allergy. The moisturizing components such as hyaluronic acid and ceramide can provide sufficient moisture and nutrition for the skin, keep the skin moist and smooth, lock the moisture in the skin and reduce moisture loss.

The present invention relates to a pharmaceutical composition for preventing or treating allergic skin diseases or skin itch, and more particularly, to a pharmaceutical composition for preventing or treating allergic skin diseases or skin itch, containing ABT-751 or TN-16 as an active ingredient, a cosmetic composition for preventing or ameliorating allergic skin diseases or skin itch, which contains ABT-751 or TN-16 as an active ingredient; and a cosmetic composition for moisturizing skin, which contains ABT-751 or TN-16 as an active ingredient. The composition for preventing or improving and treating atopic dermatitis according to the present invention effectively increases the expression of silk protein in skin cells and improves the skin barrier function, thereby having the effect of effectively improving or treating the symptoms of allergic skin diseases including atopic dermatitis or skin itch. And it is confirmed that an excellent skin moisturizing effect is exhibited.

This invention discloses a traditional Chinese medicine composition for health maintenance and deworming, and its preparation method, comprising the following raw materials in parts by weight: 12-18 parts of Artemisia annua, 8-15 parts of Rhizoma Scutellariae, 10-18 parts of Fructus Cnidii, 12-18 parts of Folium Platycladi, 8-15 parts of Radix Stemonae, 15-25 parts of Radix Smilax, 6-12 parts of Radix Sophorae Flavescentis, 10-15 parts of Cortex Dictamni, and 5-15 parts of pharmaceutical excipients, wherein the pharmaceutical excipients include soluble starch or dextrin. This invention relates to traditional Chinese medicine compositions. In the field of compound technology, this invention uses Artemisia annua as the principal drug to kill parasites and clear heat; Stemona japonica, Cnidium monnieri, and Sophora flavescens as assistant drugs to dry dampness, kill parasites, and relieve itching; Rhizoma Scutellariae, Fructus Platycladi, and Cortex Dictamni as adjuvant drugs to clear heat, detoxify, and have antibacterial and anti-inflammatory effects; and Smilax china to promote blood circulation, remove blood stasis, and have anti-inflammatory effects. The components work together to directly kill or inhibit internal and external parasites, while clearing away damp-heat toxins caused by parasite metabolism and improving accompanying symptoms such as skin itching, fatigue, and loss of appetite.

The invention provides a preparation method and preparation equipment of a skin antipruritic, relates to the technical field of preparation of skin antipruritic, and aims to solve the problems of poor material isolation and poor mixing effect of existing equipment. Through cooperation of the conveying pipe, the mixing kettle, the central pipe, the charging barrel and the movable plate, efficient loading and mixing of solid and liquid raw materials are achieved, the mixing effect is improved, and the separation and cleaning process is simplified. The motor, the gear, the belt and the rotating shaft are matched to enable the charging barrel to rotate to accelerate reaction, and the fixed plate ensures stable operation. The electric control box accurately controls temperature, the display screen displays in real time, the electric control button is convenient to control, and equipment safety is guaranteed. The universal wheels facilitate movement of the device, and the cooling fan prolongs the service life of the device. According to the preparation method, the raw materials are scientifically pretreated, mixing is accurately controlled through equipment, the prepared antipruritic can effectively relieve skin itch, and a better scheme is brought to production of the skin antipruritic.

The invention belongs to the field of daily necessities, and particularly relates to a soothing nutritional cream suitable for the skin of a diabetic patient, which takes ceramide NP, 4-tert-butyl cyclohexanol, a cynanchum atratum extract, bisabolol and a robinia pseudoacacia flower extract as main active ingredients of a repair cream, and is matched with a humectant, an emulsifier, an emollient, an antioxidant, an oil phase and a water phase matrix. The obvious effects of relieving the phenomena of decrustation, chap and the like caused by dry skin of hands and feet of the diabetic patient, strengthening the natural barrier function of the skin and relieving the symptom of skin itch are synergistically realized.

The invention belongs to the field of daily necessities, and particularly relates to a hand and foot repair cream suitable for diabetics, which is prepared by taking ceramide NP, 4-tert-butyl cyclohexanol, blackend swallowwort root extract, bisabolol and robinia pseudoacacia flower extract as main active components of the repair cream, and matching with a humectant, an emulsifier, an emollient, an antioxidant, an oil phase and a water phase matrix. The obvious effects of relieving the phenomena of decrustation, chap and the like caused by dry skin of hands and feet of the diabetic patient, strengthening the natural barrier function of the skin and relieving the symptom of skin itch are synergistically realized.

The invention belongs to the field of daily necessities, and provides moisturizing nutrition cream suitable for diabetics aiming at the problems that the skin of the diabetics is easy to dry and the skin barrier is damaged. The moisturizing and nourishing cream is prepared from the following active ingredients: dipotassium glycyrrhizinate, acetylchitosamine, phytosphingosine, bisabolol, a daisy flower extract, a betula platyphylla (BETULA ALBA) leaf extract and a honey extract. Tests of volunteers find that the moisturizing nutritional cream has a remarkable moisturizing effect and a skin barrier repairing effect, no irritating preservative or antioxidant is added, the problem of skin itch caused by irritating components is avoided, and the moisturizing nutritional cream is safe, mild and non-irritating and meets the requirement of daily skin care of diabetes patients.

The present application relates to the use of a substance that regulates BCL11A gene and / or its encoded product in the preparation of a drug for reversing skin photoaging, wherein the skin photoaging includes skin cell aging caused by sunlight, light, etc., and the skin cells include keratinocytes, dermal fibroblasts, melanocytes. The regulation is to up-regulate the expression of BCL11A gene and / or promote the production of its encoded product. Typical clinical manifestations of the skin photoaging include wrinkles, dry skin, loose skin, dilated capillaries, uneven skin pigmentation, and skin itching. The substance that regulates BCL11A gene and / or its encoded product includes a substance that regulates BCL11A gene DNA molecules and a substance that regulates the expression of BCL11A translation product protein molecules. The reversal of skin photoaging is manifested in reducing the proportion of cells positive for aging-related beta-galactosidase staining in skin cells and reducing the expression of aging-related protein p16 and DNA damage protein gammaH2AX.

This invention discloses an antipruritic gel containing 3-hydroxydecanoic acid microemulsion and its preparation method. The gel combines the natural antipruritic ingredient 3-hydroxydecanoic acid and peppermint oil. By preparing it into a microemulsion form, nano-sized droplets are combined with skin absorption enhancers and gel sustained-release agents, thereby improving transdermal absorption efficiency and prolonging the residence time in the skin to achieve a long-lasting antipruritic effect. 3-hydroxydecanoic acid exerts its antipruritic effect through anti-inflammatory action, blocking pruritus signaling pathways, and reducing mast cell degranulation. This antipruritic gel is stable at room temperature, easy to use, and suitable for relieving skin itching caused by mosquito bites, histamine, or non-histamine substances.

A composition for relieving skin itching or irritation, which contains thymol trimethoxycinnamate. This specification discloses a composition for relieving skin itching or irritation, which contains thymol trimethoxycinnamate, its stereoisomers, salts, hydrates or solvates as active ingredients, and a method for relieving skin itching or skin irritation by administering the composition to an individual in need of relieving skin itching or irritation. The composition disclosed in this specification has no side effects, and inhibits the voltage-gated sodium channel NaV1.7, thereby having an excellent effect of relieving skin itching or skin irritation.

This invention discloses a long-acting antipruritic and antibacterial topical skin preparation, comprising N-ethyl-γ-L-glutamine, 1-1-palmitoyl-2-oleoyl-sn-glycerol-3-phosphate-N-(L-γ-glutamyl-N-ethyl)-ethanolamine (POPE-N-Et-Gln-α), chlorhexidine acetate, and saffron extract as active ingredients, formulated into a hydrogel or cream with a pharmaceutically acceptable matrix. POPE-N-Et-Gln-α provides rapid transdermal action, while N-ethyl-γ-L-glutamine offers sustained-release and long-lasting effects; saffron extract provides anti-inflammatory and antioxidant effects, and chlorhexidine acetate provides antibacterial and antifungal effects. This invention is hormone-free and non-addictive, achieving both rapid and long-lasting antipruritic effects, and is suitable for eczema, urticaria, dry skin, neurodermatitis, psoriasis, microbial infections, and skin itching caused by insect bites.

The invention relates to an anti-blue-light skin care composition containing anthriscus sylvestris extract and application thereof.The anti-blue-light skin care composition is suitable for Chinese people with skin types III and above, blue light can be effectively blocked, the phenomena of skin chromatosis, aging, sensitivity, dryness and the like caused by the blue light are reduced, and the skin care effect is good. And IL-6 rise caused by blue light irradiating skin tissues is inhibited, and skin itch caused by blue light is reduced.

The invention provides a skin antibacterial ointment formula and a preparation process thereof, and relates to the field of traditional Chinese medicine ointment, and the skin antibacterial ointment formula is prepared from the following raw materials: honeysuckle, rhizoma osmundae, fructus forsythiae, rhizoma atractylodis, radix angelicae, sweet wormwood and bighead atractylodes rhizome. The antibacterial fabric has a two-layer protection effect, multiple antibacterial components synergistically play an antibacterial role, and the antibacterial effect is improved; the oil, the emulsifier, the oil phase and the water phase are added, so that skin can be moistened, inflammatory response can be relieved, and uncomfortable symptoms of skin itch can be relieved; and the preparation process is simple and easy to operate, and has wide universality.

The invention discloses a Uygur medicine composition and a preparation method thereof, belongs to the technical field of Uygur medicine, and particularly relates to a humifuse euphorbia herb fermentation and distillation integrated device and a preparation method thereof. The medicine composition comprises the following components in parts by weight: 300-500 parts of humifuse euphorbia herb and 100-300 parts of sulfur. The Uygur medicine composition disclosed by the invention integrates functions of clearing blood, relieving itching, clearing away heat and toxic materials, and can play a role in treating various skin diseases such as dermatitis, psoriasis, skin itch and the like; in application, the two medicines cooperate to achieve a treatment effect; in preparation, medicines and auxiliary materials are combined, and humifuse euphorbia herb and sulfur have a synergistic effect. The composition comprises the humifuse euphorbia herb fermentation distillation extract and the sulfur ointment for oral administration and external application, and the synergistic effect is good. According to the application, two kinds of lactobacillus plantarum and lactobacillus rhamnosus which are beneficial to repairing skin ecology are screened, a fermentation technology and herbal medicines are combined for the first time to obtain the Uygur medicine composition for treating skin diseases, equipment is innovated into fermentation and distillation integration, and a new method is provided for preparing skin treatment medicines.