Looking for breakthrough ideas for innovation challenges? Try Patsnap Eureka!

Device for removal of noxious agents from blood, extracorporeal perfusion system comprising such device and method for producing such device

An extracorporeal perfusion and harmful substance technology, applied in dialysis systems, separation methods, pharmaceutical devices, etc., can solve problems such as the complexity of hollow fiber membrane manufacturing

Pending Publication Date: 2019-08-30
B BRAUN AVITUM
View PDF10 Cites 0 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0011] However, the method disclosed in document EP 1 776 175 B1 has the disadvantage that for hollow fiber membrane / hollow fiber plasma pretreatment it requires a complex vacuum system with several vacuum chambers, therefore the hollow fiber membrane disclosed therein is very complicated to manufacture

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Image

Smart Image Click on the blue labels to locate them in the text.
Viewing Examples
Smart Image
  • Device for removal of noxious agents from blood, extracorporeal perfusion system comprising such device and method for producing such device
  • Device for removal of noxious agents from blood, extracorporeal perfusion system comprising such device and method for producing such device
  • Device for removal of noxious agents from blood, extracorporeal perfusion system comprising such device and method for producing such device

Examples

Experimental program
Comparison scheme
Effect test

Embodiment Construction

[0079] The drawings are only schematic and are used exclusively for the understanding of the invention. The same elements are provided with the same reference numerals.

[0080] figure 1 Shown is an extracorporeal perfusion system 2 according to the invention comprising a device 4 for removing harmful substances from blood. In this case, the blood of a person 6 is collected, which is pumped to the device 4 via a first line 8 by means of a first pump 10 . Such as figure 2 As shown, the device 4 includes a housing 12 and a plurality of hollow fibers 14 located within the housing 12 . In this case, the blood is basically conveyed to the hollow fibers 14 . The hollow fibers 14 are porous so that at least part of the blood plasma (blood plasma) can be sucked / pumped from the device 4 to a second line 18 by means of a second pump 16 . At least the cellular components of the blood, such as red blood cells, white blood cells or platelets, leave the device 4 through a third line 2...

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

PUM

No PUM Login to View More

Abstract

The invention relates to a device (4) in an extracorporeal perfusion system (2), the invention relates to a device for removing, in particular negatively charged harmful substances (38), the method comprises the following steps: removing blood (44) containing plasma (46) and a cell component (48); the filter comprises a shell (12) and a plurality of hollow fibers (14) arranged in the shell (12), the hollow fibers are configured to allow blood (44) to flow through. Wherein the hollow fibers (14) each have a plurality of pores (34), the hole is arranged to be a hole, wherein the hollow fibers (14) are arranged in such a way that plasma (46) of blood (44) can flow through the holes (34) from the inside of the hollow fibers (14) to the outside of the hollow fibers (14), at the same time, the hollow fibres (14) are subjected to, in particular chemical, modification or pre-treatment, such that they have a functional surface (36) that can bind to and remove the harmful substances (38) from the blood (44). The inner side surface (40) of the hollow fiber (14) is also provided with, in particular, a blood-compatible, anticoagulant, coating (50), which is designed to prevent damage to the cellular components (48) of the blood (44) when the blood (44) flows through the hollow fiber (14). The invention also relates to an extracorporeal perfusion system (2) comprising said device (4) and toa method for producing said device (4).

Description

technical field [0001] The invention relates to a device in an extracorporeal perfusion system for removing, in particular negatively charged, harmful substances from blood containing plasma and cellular components, comprising: a housing and a plurality of Hollow fibers in vivo, the hollow fibers configured to allow blood to flow therethrough, wherein the hollow fibers each have a plurality of holes arranged such that blood plasma can pass through the holes from the hollow fibers The inner side flows to the outer side of the hollow fibers, wherein the hollow fibers are modified or pretreated, in particular chemically, so that they are functional, can bind the harmful substances and remove them from the blood s surface. The invention also relates to an extracorporeal perfusion system comprising said device and a method for manufacturing said device. Background technique [0002] Sepsis, or blood poisoning, is a complex systemic inflammatory response of human tissue due to b...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

Application Information

Patent Timeline
no application Login to View More
Patent Type & Authority Applications(China)
IPC IPC(8): A61M1/36A61M1/38
CPCA61M1/3627A61M1/3673A61M1/38A61M1/34A61M1/3468A61M1/3679A61M2202/20A61M2207/00B01D39/04B01D67/0088B01D69/08B01D2239/0414B01D2239/0492B01D2323/46A61M1/3431A61M1/3437A61M1/16A61M1/3496A61M1/3621A61M1/3672A61M2205/3334
Inventor 彼得·曼德里
Owner B BRAUN AVITUM
Who we serve
  • R&D Engineer
  • R&D Manager
  • IP Professional
Why Patsnap Eureka
  • Industry Leading Data Capabilities
  • Powerful AI technology
  • Patent DNA Extraction
Social media
Patsnap Eureka Blog
Learn More
PatSnap group products

Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic, Popular Technical Reports.

© 2024 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap|About US| Contact US: help@patsnap.com