Gastrointestinal tract sampling and drug releasing capsule
A gastrointestinal tract and capsule technology, which is applied in the field of medical appliances, can solve the problems of inconvenient sampling of the stomach and intestine, and the inability to intuitively understand the environment of the stomach and intestine, and achieves compact structure, low manufacturing cost, and convenient use Effect
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Embodiment 1
[0021] Such as figure 1 As shown, a drug release capsule for gastrointestinal tract sampling, the capsule has a shell 1, a sampling tube 2, at least one layer of inner core 3 arranged in the shell 1 and an annular area surrounded by adjacent layers, the annular area is arranged in the layer The partitions 4 between the partitions are separated up and down, the annular area above the partition is the drug release area 5, and the annular area below the partition 4 is the sample collection area 6; There are at least two drug release holes 11 at the position, at least one drug release hole 11 is connected to one end of the sampling tube 2, and the other end of the sampling tube 2 is connected to the sample collection area 6; the drug release hole 11 is provided with a sealing film (not shown in the figure), the sealing film is made of a material that can be digested in a specific environment, and the shell 1 and the inner core 3 are made of a medical material that cannot be digest...
Embodiment 2
[0027] Such as figure 2 As shown, on the basis of Example 1, specifically, the gastrointestinal tract sampling drug release capsule has a first inner core 31 (located in the shell) and a second inner core 32, the second inner core 32 is arranged in the first inner core 31, and the outer shell 1 is provided with gastric drug release hole 111, and gastric drug release hole 111 is provided with a gastrolytic coating film; the first inner core 31 is provided with intestinal drug release hole 112, and the intestinal drug release hole 112 is provided with Has an enteric coating. Drugs for treating stomach diseases can be placed in the drug release area 5 between the shell 1 and the first inner core 31, and drugs for treating intestinal diseases can be placed in the drug release area 5 between the first inner core 31 and the second inner core 32 medicines. When the gastrointestinal tract sample release capsule enters the stomach, the sealing film at the drug release hole 111 in th...
Embodiment 3
[0029] Such as image 3 As shown, on the basis of Example 2, the drug release hole 111 in the stomach and the drug release hole 112 in the intestine can be arranged correspondingly, and the drug release hole 111 in the stomach is larger than the drug release hole 112 in the intestine, that is, the drug release hole in the intestine 112 is set within the opening range of the drug release hole 111 in the stomach, so that the drug stored in the drug release area 5 between the first inner core 31 and the second inner core 32 can more quickly and fully realize contact with the intestinal environment.
[0030] In order to achieve the purpose of sampling at different positions in the body, on the basis of any of the above-mentioned technical solutions, the sample collection area 6 can be separated into a structure with a plurality of sealed sample collection cavities 61, and the sample collection cavities 61 are respectively connected to the Different sampling tubes 2 are connected, ...
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