Peppermint mouthwash tablet containing artificial saliva and preparation method of peppermint mouthwash tablet

A technology of artificial saliva and mouthwash tablets, applied in the field of oral hygiene products, can solve the problems of insufficient dissolution, affecting cleaning effect, slow dissolution speed, etc., and achieves good oral cleaning and breath freshening effect, fast dissolution speed and low cost. Effect

Inactive Publication Date: 2019-10-08
PANZHIHUA UNIV +2
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, the above-mentioned mouthwash tablets all need extra drinking water when used. If the dissolution rate is too slow through the effect of oral saliva, it may not even f

Method used

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  • Peppermint mouthwash tablet containing artificial saliva and preparation method of peppermint mouthwash tablet
  • Peppermint mouthwash tablet containing artificial saliva and preparation method of peppermint mouthwash tablet
  • Peppermint mouthwash tablet containing artificial saliva and preparation method of peppermint mouthwash tablet

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Experimental program
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Effect test

Embodiment 1

[0078] The preparation of embodiment 1 mouthwash tablet of the present invention

[0079] a, granulation: by mass percentage, take menthol 10%, chlorogenic acid 30%, artificial saliva 2.5%, citric acid: sodium bicarbonate (0.4:0.5, w:w) 40%, PVPP 6%, wood Sugar alcohol 10%, PEG6000 1.5%, stirring and mixing, 60% ethanol wet granulation, prepared into granules;

[0080] b. Whole-grain tabletting: the granule mixture prepared in step a is placed into a tablet press for tableting to obtain regular and smooth sheet-like products;

[0081] c. Packaging: choose light aluminum-plastic film packaging to make the finished product.

[0082] Take 6 mouthwash tablets (tablet weight 0.5g), test the disintegration time limit in artificial saliva, and all the tablets disintegrate and dissolve within 30s.

Embodiment 2

[0083] The preparation of embodiment 2 mouthwash tablet of the present invention

[0084] In terms of mass percentage, menthol 15%, tea polyphenols 10%, artificial saliva 0.5%, citric acid: sodium bicarbonate (0.4:0.5, w:w) 50%, PVPP 8%, xylitol 15%, PEG6000 1.5%, stirring and mixing, wet granulation with 95% ethanol, prepared into granules, whole granules compressed into tablets, packaged in aluminum-plastic film, and ready to be obtained.

Embodiment 3

[0085] The preparation of embodiment 3 mouthwash tablet of the present invention

[0086] In terms of mass percentage, menthol 5%, tea polyphenols 10%, chlorogenic acid 30%, artificial saliva 1.5%, citric acid: sodium bicarbonate (0.4:0.5, w:w) 30%, PVPP 7%, Xylitol 15%, PEG6000 1.5%, stirring and mixing, 60% ethanol wet granulation, prepared into granules, the whole granules are compressed into tablets, and packaged with aluminum-plastic film.

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Abstract

The invention relates to a peppermint mouthwash tablet containing artificial saliva and a preparation method thereof, and belongs to the field of oral hygiene products. The peppermint mouthwash tabletcontaining the artificial saliva contains peppermint ingredients, and the artificial saliva, disintegrating agent, carbonate and/or bicarbonate, acid agent and filler. Compared with traditional toothpastes, mouthwash tablets and other oral cleaning products, the peppermint mouthwash tablet does not need to drink water additionally after improvement, after entering an oral cavity, the peppermint mouthwash tablet can be dissolved quickly through a small amount of saliva in the oral cavity, and can be completely dissolved within 30s as soon as possible, and in addition, the peppermint mouthwashtablet has the advantages of good oral cleaning and breath refreshing effects, low costs, and wide market prospects.

Description

technical field [0001] The invention relates to a mint mouthwash tablet containing artificial saliva and a preparation method thereof, belonging to the field of oral hygiene products. Background technique [0002] With the development of the food industry and the improvement of people's living standards, people pay more and more attention to oral hygiene, and new products such as chewing gum and mouthwash have been gradually developed on the basis of traditional oral cleaning product toothpaste. However, the use of both mouthwash and chewing gum has its limitations and hazards. [0003] Long-term use of mouthwash can cause an imbalance in the normal flora in the mouth, and in severe cases, ulcers may form, and may increase the risk of diabetes. Frequent use of mouthwash also increases the risk of heart disease and stroke. Children should use mouthwash with caution to prevent the mouthwash from being accidentally swallowed and causing irritation to the child's stomach. Mor...

Claims

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Application Information

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IPC IPC(8): A61K8/81A61K8/40A61K8/365A61K8/34A61K8/24A61K8/23A61K8/19A61K8/02A61Q11/00
CPCA61K8/0208A61K8/19A61K8/23A61K8/24A61K8/34A61K8/345A61K8/365A61K8/40A61K8/8176A61K2800/222A61Q11/00
Inventor 田金凤尚远宏付仪李智虓洪璐金恒屹杜娇
Owner PANZHIHUA UNIV
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