Combination drug for preparing externally-used drug for treating internal hemorrhoids and preparation method of combination drug

A technology of compound medicine and internal hemorrhoids, which is applied in the field of preparation of the medicine, can solve problems such as complex administration methods, anal mass prolapse, and internal dampness in patients, and achieve good therapeutic effects, reduce toxic and side effects, and have good curative effects

Inactive Publication Date: 2019-11-08
高世林
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

(2) Damp-heat betting, which is mostly due to the patient's dietary problems. The patient eats more raw, cold, and greasy food, which causes the patient to breed internal dampness. When the blood is in general, the meridians are intertwined to produce internal hemorrhoids, the heat will force the blood to flow, the blood will not circulate, blood in the stool will appe

Method used

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  • Combination drug for preparing externally-used drug for treating internal hemorrhoids and preparation method of combination drug
  • Combination drug for preparing externally-used drug for treating internal hemorrhoids and preparation method of combination drug
  • Combination drug for preparing externally-used drug for treating internal hemorrhoids and preparation method of combination drug

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Experimental program
Comparison scheme
Effect test

Embodiment 1

[0032]Embodiment one: the preparation of compound medicament

[0033] The invention provides a compound medicament, which comprises 20%-40% of main drug and 60%-80% of matrix in terms of weight percentage.

[0034] In the present invention, the base may be a suppository base or an ointment base.

[0035] Specifically, the main drug in the present invention, by weight percentage, includes 24-26% of keel, 3-5% of Chuanbei, 3-5% of Galla gall, 12-15% of talcum powder, 6-8% of Burnet chinensis, comfrey 4-6%, Panax notoginseng 3-5%, Bletilla striata 3-5%, Borax 12-15%, Dacronine 4-6%, Lidocaine 9-12%, Paraben 0.4-0.7%, Borneol 4-6%.

[0036] Specifically, the suppository base of the present invention is a mixed fatty acid glyceride.

[0037] Specifically, the ointment base in the present invention includes, by weight, 8-10 parts of vaseline, 6-9 parts of lanolin, 1-2 parts of beeswax, and 2-4 parts of yellow wax.

Embodiment 2

[0038] Embodiment two: the preparation of compound medicament

[0039] The invention provides a compound medicament, which comprises 20% main drug and 80% base by weight percentage.

[0040] In the present invention, the base may be a suppository base or an ointment base.

[0041] Preferably, the main drug in the present invention includes 25.5% of keel, 4% of Chuanbei, 4% of Galla gall, 13% of talcum powder, 7% of Burnet, 5% of comfrey, 4% of Panax notoginseng, and Bletilla striata in parts by weight. 4%, borax 13%, dyclonine 4.5%, lidocaine 11%, paraben 0.5%, borneol 4.5%.

[0042] Specifically, the suppository base of the present invention is a mixed fatty acid glyceride.

[0043] Preferably, the ointment base in the present invention comprises 9 parts of vaseline, 7 parts of lanolin, 1 part of beeswax and 3 parts of yellow wax in parts by weight.

Embodiment 3

[0044] Embodiment three: the preparation of compound medicine

[0045] (1) The main drug raw materials, keel, Chuanbei, gallnut, talcum powder, Burnet, comfrey, Panax notoginseng, Bletilla striata, borax, dyclonine, lidocaine, paraben, borneol, selected to remove impurities Grind the fine powder separately, filter through a No. 6 medicine sieve, and mix in proportion;

[0046] (2) Stir the mixed main drug raw material powder prepared in step (1) with the mixed fatty acid glycerides melted to 60°C, pour 2.0-2.5g of each suppository into the suppository mold, open the mold after cooling, and put The prepared suppository can be used after being taken out of the box;

[0047] (3) Heat medical vaseline, lanolin, beeswax, and yellow wax to form a paste, then add the mixed main drug raw material powder prepared in step (2) into the ointment base, and make a paste to prepare an ointment for use.

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Abstract

The invention discloses a combination drug and application thereof. The combination drug is prepared from 20% of a main drug and 80% of a matrix, wherein the main drug is prepared from 24-26% of dragon bones, 3-5% of bulbus fritilariae, 3-5% of Chinese gall, 12-15% of talcum powder, 6-8% of sanguisorba officinalis, 4-6% of radix lithospermi, 3-5% of pseudo-ginseng, 3-5% of bletilla striata, 12-15%of borax, 4-6% of dyclonine, 9-12% of lidocaine, 0.4-0.7% of nipagin, and 4-6% of borneol; and the ointment matrix is prepared from 8-10 parts of Vaseline, 6-9 parts of lanolin, 1-2 parts of beewax and 2-4 parts of yellow wax. A prepared combination drug suppository has effects on lesions in all stages of internal hemorrhoid bleeding and internal hemorrhoid prolapse, absorption is fast through rectal administration, the suppository slowly dissolves for 24 hours to directly act on local lesions, and the treatment effect is remarkable; the effect is the best through anal administration, and internal hemorrhoids are basically healed after 2-3 courses of treatment; and the drug is high in permeability and can directly reach lesions, meanwhile, a preparation method is simple, operation is easy, and wide application and popularization value is achieved.

Description

technical field [0001] The invention belongs to the technical field of traditional Chinese medicines. Specifically, the invention relates to a medicine for external use prepared with a combination of Chinese and Western medicines as a raw material. The invention also relates to a preparation method of the medicine, in particular to the technical field of an ointment for external use for treating internal hemorrhoids . Background technique [0002] Traditional Chinese medicine treats the symptoms and cures the root cause, has no toxic and side effects, and is quite accepted and selected by people. Chinese medicine has been widely used in the treatment of various diseases, and the effect is good. [0003] Internal hemorrhoids are a common and frequently-occurring disease. Internal hemorrhoids are varicose venous plexus under the anal canal and submucosal end of the rectum, resulting in the formation of meridian clusters. The clinical manifestations of internal hemorrhoids are ...

Claims

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Application Information

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IPC IPC(8): A61K36/898A61K9/06A61K47/14A61P9/14A61K31/045A61K31/167A61K31/4453A61K33/12A61K33/22A61K35/02A61K35/64
CPCA61K9/0031A61K9/06A61K31/045A61K31/167A61K31/4453A61K33/12A61K33/22A61K35/02A61K35/64A61K36/258A61K36/30A61K36/739A61K36/8966A61K36/898A61K47/14A61P9/14A61K2300/00
Inventor 高世林
Owner 高世林
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