United multi-cell tracking method based on label ant colony

A multi-cellular, labeling technology, applied in the field of automatic tracking, which can solve problems such as deformation and cell division

Active Publication Date: 2019-12-20
JIANGSU SAIKANG MEDICAL EQUIP
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AI Technical Summary

Problems solved by technology

[0009] In order to solve the tracking problems such as cell division, deformation and measurement uncertainty, the prese

Method used

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  • United multi-cell tracking method based on label ant colony
  • United multi-cell tracking method based on label ant colony
  • United multi-cell tracking method based on label ant colony

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Embodiment 1

[0105] 1. The definition and approximation of Dobenuli stochastic finite ant colony:

[0106] Do Bernoulli random finite ant colony: Do Bernoulli random finite ant colony X consists of a fixed number (such as M) of single Bernoulli random finite ant colony X (ζ) (ζ=1,...,M), and each single Bernoulli random finite ant colony X (ζ) Can use its existence probability r (ζ) ∈(0,1) and its corresponding probability density function π (ζ) To indicate that, therefore, the Do Bernoulli random finite ant colony X can be used with the Bernoulli parameter ant colony To represent. Multiple labels, Bernoulli random finite ant colony available {(r (ζ) ,π (ζ) ): ζεΨ} means, where Ψ represents the index ant colony, if a single Bernoulli component returns a non-empty ant colony, it is given a label.

[0107] Tag Dobernulli random finite ant colony approximation: Tag Dobernulli random finite ant colony can be approximated by tag Dobernulli ant colony, namely Where Ψ a Represents the ant colony inde...

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Abstract

The invention discloses a united multi-cell tracking method based on a label ant colony. The method comprises the following steps: firstly, generating a group of cell candidate ant colonies in a current frame by adopting a label-free scouting ant colony, constructing a bipartite graph on the basis of the cell candidate ant colonies, and forming the bipartite graph by a cell state estimated in theprevious frame and the currently generated cell candidate ant colonies; secondly, optimally realizing inter-frame matching by utilizing the label ant colony and taking track optimal sub-mode distribution as a target function, wherein the multi-cell state is obtained by multi-Bernoulli parameters approximate to the evolved label ant colony, and the spectrum tree of the cells is obtained by extracting a track pheromone field on inter-frame matching determined by the spectrum tree; finally, providing a four-step flight path recovery method for flight path breakage so as to realize correlation between broken flight paths. According to the method, the spectrum coefficient of the cell can be extracted by utilizing the track pheromone, and the state of the cell is estimated by utilizing the foodpheromone; compared with the prior art, the cell division accuracy and recall rate are obviously improved.

Description

Technical field [0001] The invention belongs to the field of automatic tracking, and more specifically relates to a combined multi-cell tracking method based on tag ant colonies. Background technique [0002] Quantitative analysis of cell behavior requires reliable automatic tracking technology, and can automatically estimate the state, morphological parameters and corresponding lineage trees related to each cell. Manual tracking requires high professional level of experimenters, and is time-consuming, difficult to replicate results, difficult to parallel tracking, error-prone, etc. Therefore, integrated automatic tracking technology is the main research focus of cell tracking in recent years. [0003] At present, there are many automatic multi-cell tracking methods, such as: segmentation and correlation method, model evolution method, and filtering method. The segmentation and correlation method is currently an effective way to solve the problem of multi-cell division tracking wi...

Claims

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Application Information

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IPC IPC(8): G06N3/00G06F17/18
CPCG06F17/18G06N3/006
Inventor 徐本连鲁明丽陈庆兰施健孙乙丹
Owner JIANGSU SAIKANG MEDICAL EQUIP
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