Wearable photoelectrochemical biosensor and preparation method thereof

A biosensor and photoelectrochemical technology, applied in the field of wearable sensing, can solve the problems of inability to timely and accurately reflect the health status of the human body, the inability to monitor blood sugar concentration anytime and anywhere, and the large background current, so as to achieve easy promotion and use, structure Simple, low background current effect

Pending Publication Date: 2020-02-21
NANJING UNIV
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Conventional blood sugar monitoring methods often require blood tests in hospitals or regular clinics. It is an invasive, point-based measurement method that cannot monitor blood sugar concentrations anytime and anywhere; however, existing wearable biosensors are mostly based on electrochemical principles. The background current is large and the detection limit is high. For low currents, the detection results cannot be obtained in time, and the health status information of the human body cannot be accurately reflected in a timely manner.

Method used

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  • Wearable photoelectrochemical biosensor and preparation method thereof
  • Wearable photoelectrochemical biosensor and preparation method thereof
  • Wearable photoelectrochemical biosensor and preparation method thereof

Examples

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Embodiment

[0034] Example: Monitoring of Glucose Concentration in User's Sweat

[0035] Such as figure 1 , a wearable photoelectrochemical biosensor of the present invention includes a laser light source 1, an optical fiber, a micro-optical fiber 6, an electrode 3, a photoelectric material 4 and an enzyme 5, and the optical fiber includes an incident optical fiber 2 and an outgoing optical fiber 7, which are respectively arranged on two sides of the sensor. The incident fiber 2 is set at the output end of the laser light source 1, a section of micro-fiber 6 is connected between the incident fiber 2 and the exit fiber 7, the photoelectric material 4 is arranged on the micro-fiber 6, and the electrode 3 is continuously plated on the outside of the fiber and the fiber and micro-fiber 6 Outside the connection end, the enzyme 5 is modified on the photoelectric material 4 and reacts with sweat. The light emitted by the laser light source 1 enters the incident optical fiber 2, and the light emi...

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Abstract

The invention discloses a wearable photoelectrochemical biosensor and a preparation method thereof. The biosensor comprises a laser light source, an optical fiber, a micro optical fiber, electrodes, aphotoelectric material and an enzyme. The optical fiber comprises an incident optical fiber and an emergent optical fiber arranged at two ends of the sensor respectively, the incident optical fiber is arranged at an output end of the laser light source, the micro optical fiber is connected between the incident optical fiber and the emergent optical fiber, the photoelectric material is arranged onthe micro optical fiber, and the electrodes are continuously plated outside the optical fiber and connecting ends of the optical fiber and the micro optical fiber. The wearable photoelectrochemical biosensor can be applied to a skin patch or fabric, sweat secretion on a surface of a skin is dynamically monitored in real time in 24 hours, the concentrations of glucose, lactic acid and the like areanalyzed, and human health condition information is fed. The structure is simple, the preparation method is mature in process, the preparation cost is low, and the popularization and use are easy.

Description

technical field [0001] The invention relates to the field of wearable sensing, in particular to a wearable photoelectrochemical biosensor and a preparation method thereof. Background technique [0002] With the introduction of the wearable concept and the development of sensor technology, many kinds of wearable devices have emerged on the market, which can monitor people's physiological signals, such as heart rate, blood oxygen, etc., and provide a hardware foundation for users' health monitoring and precision medicine. . [0003] In terms of skin surface biosensors, non-invasive detection of glucose and lactic acid concentration has attracted people's attention. The glucose content in sweat is related to the blood sugar level of the human body, and the lactic acid level reflects the aerobic and anaerobic state of the human body. Therefore, sweat detection plays an important role in human health. Monitoring and motion monitoring play an important role. Conventional blood s...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): G01N27/327G01N27/30
CPCG01N27/305G01N27/3272
Inventor 徐飞朱衡天熊毅丰陆延青胡伟
Owner NANJING UNIV
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