Drug trace detection test strip, preparation method thereof and drug trace detection kit

A technology for testing test strips and test strips, applied in biological testing, measuring devices, material inspection products, etc., can solve the problems of single sample, complicated sampling, complicated operation, etc., to improve detection efficiency, avoid sample addition operations, and improve detection. The effect of efficiency

Inactive Publication Date: 2020-02-28
佛山墨赛生物技术有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] At present, the drug detection test strips on the market are mainly used to detect urine, and some can detect saliva or hair. Facing the complex sampling environment and personnel, there are complex sampling, single sample, and insufficient sampling volume. Saliva chromatography process Too slow, low sensitivity, drugs in the blood are easy to metabolize and decompose, the cycle is short, common test strips can detect few types of drugs at one time, etc., the cost is relatively high, the operation is relatively complicated, and professionals in the industry are required

Method used

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  • Drug trace detection test strip, preparation method thereof and drug trace detection kit
  • Drug trace detection test strip, preparation method thereof and drug trace detection kit
  • Drug trace detection test strip, preparation method thereof and drug trace detection kit

Examples

Experimental program
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Effect test

Embodiment 1

[0045] see figure 1 As shown, this embodiment provides a drug trace detection test strip 10 , which includes a test strip body 200 .

[0046] The test strip body 200 includes a base 210 and a sample pad 220 , a binding pad 230 , a detection film 240 and an absorbent pad 250 arranged on the base 210 and sequentially connected from one end to the other end of the base 210 .

[0047] The binding pad 230 is provided with time-resolved fluorescent microsphere-labeled specific monoclonal antibodies of the six drugs. In this embodiment, the binding pad 230 is equipped with time-resolved fluorescent microspheres labeled with six kinds of drugs and specific monoclonal antibodies customized by Hangzhou Taixi Biology, which can specifically bind to the small molecules of the detected drugs with high efficiency. The detection film 240 has at least six detection lines 242 respectively corresponding to the six drugs. Each detection line 242 is coated with a corresponding drug synthetic an...

Embodiment 2

[0058] This embodiment provides a drug trace detection kit 10 , which includes a whole biological sample diluent 300 , a quantitative pipette 400 and the drug trace detection test strip 10 of Embodiment 1.

[0059] The detectable sample types of the drug trace detection kit 10 include: drug powder, blood, urine, saliva and hair, and the hair includes hair, pubic hair, leg hair and armpit hair.

[0060] The mass ratio of the detectable sample to the whole biological sample diluent 300 is 1:25-300.

Embodiment 3

[0062] The present embodiment provides a kind of preparation method of drug trace test strip 10, and it comprises the steps:

[0063] (1) Uniformly coat the specific monoclonal antibody solutions of the six drugs labeled with time-resolved fluorescent microspheres on the binding pad 230 and dry them; respectively streak the synthetic antigen solutions of the six drugs on the detection membrane 240 to form The detection line 242 corresponding to different drugs is dry; the six drugs are morphine, amphetamines, ketamine, THC, cannabinoids and cocaine.

[0064] (2) Adhering the sample pad 220 , the binding pad 230 , the detection film 240 and the absorbent pad 250 on the surface of the base 210 from one end to the other end of the base 210 to form the test strip body 200 .

[0065] (3) The test strip body 200 is installed in the detection cavity of the detection card holder 100, and the sample pad 220 is located in the sample slot 102 of the detection card holder 100, and the det...

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Abstract

The invention discloses a drug trace detection test strip, a preparation method thereof and a drug trace detection kit. The drug trace detection test strip comprises a test strip body, wherein the test strip body comprises a substrate, and a sample pad, a combination pad, a detection film and an absorption pad which are arranged on the substrate and are sequentially connected from one end to the other end of the substrate; the combination pad is provided with at least one time-resolved fluorescent microsphere-labeled specific monoclonal antibody of drugs; the detection film is provided with atleast one detection line corresponding to each drug; each detection line is coated with a synthetic antigen of the corresponding drug; and the six drugs are one or more of morphine, phenylalanine, ketamine, tetrahydrocannabinol, cannabis synthetic hormone and cocaine. The drug trace detection test strip has the advantages of high detection speed, low cost and simple operation.

Description

technical field [0001] The invention relates to the field of drug detection, in particular to a drug trace detection test strip, a preparation method thereof and a drug trace detection kit. Background technique [0002] Drugs not only affect the health of drug addicts, but also harm the families of drug addicts, and the family is the foundation of society and the country. In order to crack down on drugs, countries around the world have stepped up their efforts and invested a lot of manpower, material and financial resources to strengthen anti-drug awareness education and drug testing scientific research technology. There are many types of drugs at present, but drug addicts are mainly concentrated in drugs such as morphine, amphetamines, ketamine, marijuana, and cocaine. [0003] At present, the drug detection test strips on the market are mainly used to detect urine, and some can detect saliva or hair. Facing the complex sampling environment and personnel, there are complex...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): G01N33/58G01N33/577G01N33/558
CPCG01N33/558G01N33/577G01N33/582
Inventor 谭有将梁德智漆彦斌陈静李伟伟熊伟锦陈晓婷梁婷婷沈润林高玉洁
Owner 佛山墨赛生物技术有限公司
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