Application of irisin in production of anti-inflammatory medicines

Abstract

The invention discloses application of irisin in production of anti-inflammatory medicines, and relates to the technical field of medicines. A production method of the irisin anti-inflammatory medicines specifically comprises the following step: (1) producing a combined non-steroid anti-inflammatory medicine: firstly, respectively selecting 20-30 parts of aspirin, 10-20 parts of acetaminophen, 5-10 parts of indometacin, 5-10 parts of naproxen and 5-10 parts of nabumetone on the basis of total weight parts of the non-steroid anti-inflammatory medicine, and sequentially adding the selected 20-30parts of aspirin, 10-20 parts of acetaminophen, 5-10 parts of indometacin, 5-10 parts of naproxen and 5-10 parts of nabumetone into a grinder for full grinding and mixing until the granularity of themedicine is 100-150 meshes, so as to obtain the combined non-steroid anti-inflammatory medicine. According to application of the irisin in production of the anti-inflammatory medicines, by adding theirisin into the non-steroid medicines, anti-inflammatory effects of the anti-inflammatory medicines can be improved, the anti-inflammatory purpose can be achieved by the irisin which inhibits expression of inflammatory factors and activation of inflammatory signal pathway key signal molecules NF-kappaB-p65 and p38, the anti-inflammatory medicines are suitable for infective inflammation and non-infective inflammation, and a patient does not need to take large doses of the anti-inflammatory medicines for a long term to achieve a required curative effect, so that a healthy life of the patient isguaranteed.

Description

technical field [0001] The invention relates to the technical field of medicine, in particular to the application of irisin in the preparation of anti-inflammatory drugs. Background technique [0002] Inflammation is a very common and important basic pathological process. Trauma infection on the body surface and most common and frequently-occurring diseases of various organs (such as boils, carbuncles, pneumonia, hepatitis, nephritis, etc.) are all inflammatory diseases, with vascular system The defensive reaction of living tissues to injury factors is called inflammation, and the defense reaction of living tissues with vascular system to injury factors is inflammation. Vascular response is the central link of the inflammatory process. Or indirectly cause tissue and cell damage, on the other hand, through inflammatory hyperemia and exudative reaction, to dilute, kill and surround the damage factor, and at the same time, the damaged tissue can be repaired and healed through t...

AI Technical Summary

Problems solved by technology

[0005] Aiming at the deficiencies of the prior art, the present invention provides an application of irisin in the preparation of anti-inflammatory drugs, which solves the problem that the existing antibiotics are only effective for infectious inflammation, but not effective for non-infectious inflammation, and the existing glucocorticoids Anti-inflammatory drugs and non-steroidal anti-inflammatory drugs to achieve the expected anti-inflammatory effect, need to take a large number of anti-inflammatory drugs for a long time, and long-term large-scale use of such anti-inflammatory drugs will produce adverse reactions, the problem of large side effects