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Application of traditional Chinese medicinal composition in preparation of medicines for treating intestinal dysbacteriosis

A technology of intestinal flora imbalance and composition, which is applied in the direction of drug combination, medical raw materials derived from arthropods, plant/algae/fungus/moss components, etc., can solve problems such as chronic diarrhea, deficiency, and flora imbalance, and achieve Reasonable compatibility and small adverse reactions

Inactive Publication Date: 2020-05-22
SHIJIAZHUANG YILING PHARMA
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Once the gastrointestinal mucosa synthesizes monomeric or binary IgA, or the synthesis of secretory flakes malfunctions, resulting in the lack of typing IgA in the gastrointestinal secretions, it can cause excessive reproduction of aerobic and anaerobic bacteria in the small intestine, resulting in bacterial infection. group disorder, causing chronic diarrhea

Method used

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  • Application of traditional Chinese medicinal composition in preparation of medicines for treating intestinal dysbacteriosis

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0038] The formula of raw materials is: Astragalus 250g, Ligustrum lucidum 200g, Ginseng 65g, Ganoderma lucidum 65g, Curcuma 132g, Fried Atractylodes 64g, Banzhilian 128g, Gynostemma 256g, Poria cocos 65g, Gallus chinensis 30g, Snakeberry 128g, Baiying 128g, Yin Chen 128g, Xu Changqing 128g, Wood Beetle 20g, Hedyotis diffusa 128g.

[0039] The preparation method is:

[0040] (1), take the Chinese medicinal material according to the weight ratio of the crude drug, and select it;

[0041] (2) For ginseng and Ligustrum lucidum, add 8 times the amount of 70% ethanol for reflux extraction twice, the first time for 3 hours, and the second time for 2 hours, combine the extracts, recover the ethanol until there is no alcohol smell, and the filtrate and ginseng, female Residues of chastity seeds for use;

[0042] (3) Curcuma, Atractylodes Rhizome (stir-fried), and Xu Changqing were combined to extract the volatile oil, the oil extraction time was 8 hours, the volatile oil was collect...

Embodiment 2

[0048] The formula of raw materials is: Astragalus 360g, Ligustrum lucidum 100g, Ginseng 95g, Ganoderma lucidum 30g, Curcuma 195g, Fried Atractylodes macrocephala 30g, Scutellaria barbata 195g, Gynostemma 120g, Poria 95g, Gallus gallinaceae 15g, Snakeberry 195g, Baiying 65g, Yin Chen 195g, Xu Changqing 65g, Wood Beetle 30g, Hedyotis diffusa 65g.

[0049] The preparation method is:

[0050] (1), take the Chinese medicinal material according to the weight ratio of the crude drug, and select it;

[0051] (2), ginseng, Ligustrum lucidum, add 6 times the amount of 90% ethanol to reflux and extract for 4 hours, recover the ethanol from the extract until there is no alcohol smell, and the filtrate and ginseng, Ligustrum lucidum residues are for subsequent use;

[0052] (3) Merge Curcuma, Atractylodes Rhizoma Atractylodes Rhizome (stir-fried), and Xu Changqing, add 4 times the amount of water to extract the volatile oil, the oil extraction time is 10 hours, collect the volatile oil i...

Embodiment 3

[0058] The formula of raw materials is: Astragalus 120g, Ligustrum lucidum 300g, Ginseng 30g, Ganoderma lucidum 95g, Curcuma 65g, Atractylodes rhizome 90g, Scutellaria barbata 65g, Jiaogulan 360g, Poria cocos 30g, Gallus chinensis 45g, Snakeberry 65g, Baiying 195g, Yin Chen 65g, Xu Changqing 195g, wood beetle 10g, Hedyotis diffusa 195g.

[0059] The preparation method is:

[0060] (1), take the Chinese medicinal material according to the weight ratio of the crude drug, and select it;

[0061] (2) For ginseng and Ligustrum lucidum, add 10 times the amount of 50% ethanol to reflux and extract twice, the first time for 3 hours, and the second time for 2 hours, combine the extracts, recover the ethanol until there is no alcohol smell, and the filtrate and ginseng, female Residues of chastity seeds for use;

[0062] (3) Merge Curcuma, Atractylodes Rhizoma Atractylodes Rhizome, and Xu Changqing, add 10 times the amount of water to extract the volatile oil, the oil extraction time ...

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Abstract

The invention relates to the field of traditional Chinese medicine. A traditional Chinese medicinal composition for treating intestinal dysbacteriosis is prepared from the following medicinal raw materials in parts by weight: 120-360 parts of radix astragali, 100-300 parts of fructus ligustri lucidi, 30-95 parts of ginseng, 30-95 parts of lucid ganoderma, 65-195 parts of rhizoma curcumae, 30-90 parts of rhizoma atractylodis macrocephalae, 65-195 parts of herba scutellariae barbatae, 120-360 parts of gynostemma pentaphyllum, 30-95 parts of poria cocos, 15-45 parts of endothelium corneum gigeriae galli, 65-195 parts of duchesnea indica, 65-195 parts of solanum lyratum thunb, 65-195 parts of herba artemisiae scopariae, 65-195 parts of radix cynanchi panicullati, 10-30 parts of ground beeltlesand 65-195 parts of oldenlandia diffusa. The medicine can be used for effectively treating intestinal dysbacteriosis. Tests prove that the traditional Chinese medicinal composition has exact curativeeffect and relatively good market prospect.

Description

technical field [0001] The invention relates to a new application of a traditional Chinese medicine composition, in particular to an application of a traditional Chinese medicine composition in the preparation of medicines for treating intestinal flora disorders. Background technique [0002] The gastrointestinal tract of healthy people is home to a wide variety of microorganisms, which are called gut flora. The intestinal flora is combined in a certain proportion, and each bacteria restricts and depends on each other to form an ecological balance in terms of quality and quantity. Once the internal and external environment of the body changes, especially long-term use of broad-spectrum antibiotics, sensitive intestinal bacteria will be inhibited , Uninhibited bacteria take the opportunity to reproduce, causing flora imbalance, destroying its normal physiological combination, resulting in pathological combination and causing clinical symptoms, which is called intestinal flora...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/9066A61P1/00A61K35/57A61K35/64
CPCA61K36/481A61K36/638A61K36/258A61K36/074A61K36/9066A61K36/284A61K36/539A61K36/424A61K36/076A61K35/57A61K36/73A61K36/81A61K36/282A61K36/27A61K35/64A61K36/748A61P1/00A61K2236/333A61K2236/39A61K2236/331A61K2236/51A61K2300/00
Inventor 贾振华张喜芬王伟
Owner SHIJIAZHUANG YILING PHARMA
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