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Clinical-based automated delivery of treatment substances to the inner ear

A substance, curative effect technology, applied in the field of clinical-based automated delivery of therapeutic substances to the inner ear

Active Publication Date: 2020-05-22
COCHLEAR LIMITED
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Individuals with sensorineural hearing loss do not benefit adequately from hearing prostheses that generate mechanical movement of cochlear fluid

Method used

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  • Clinical-based automated delivery of treatment substances to the inner ear
  • Clinical-based automated delivery of treatment substances to the inner ear
  • Clinical-based automated delivery of treatment substances to the inner ear

Examples

Experimental program
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Embodiment Construction

[0016] Embodiments presented herein generally relate to clinically based automated administration / control (e.g., initiate, adjust, modify, etc.) delivery of a therapeutic substance to at least one inner ear of a recipient of an implantable medical device to treat an inner ear disorder (e.g., tinnitus, hearing loss, tinnitus, Meniere's disease, etc.). More specifically, according to embodiments presented herein, in vivo biomarkers are analyzed to determine the biological state / condition of one or more physiological elements of the inner ear. Based on the determined biological state of the one or more physiological elements of the inner ear, subsequent delivery of one or more therapeutic substances to the inner ear of the recipient is controlled. Using the biological state of one or more physiological elements ensures that subsequent delivery of the therapeutic substance remains within the desired therapeutic window (ie, is clinically effective and does not have toxic effects). ...

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Abstract

Presented herein are techniques for clinical-based automated control of the delivery of treatment substances to at least one inner ear of a recipient of an implantable medical device. More specifically, in-vivo biomarkers are analyzed to determine a biological state / status of one or more physiological elements of the inner ear. Subsequent delivery of one or more treatment substances to the inner ear of the recipient are controlled based on the determined biological state of the one or more physiological elements of the inner ear.

Description

[0001] background technical field [0002] The present invention relates to clinically based automated delivery of a therapeutic substance to the inner ear of a recipient. Background technique [0003] A large percentage of the world's population suffers from some form of inner ear impairment, such as conductive and / or sensorineural hearing loss, tinnitus, Meniere's disease or other balance disorders. The main treatment for inner ear disorders is based on auditory prostheses that stimulate the inner ear mechanically and / or electrically. For example, individuals with conductive hearing loss often receive auditory prostheses that produce fluid movement in the cochlea. Such hearing prostheses include, for example, acoustic hearing aids, bone conduction devices, electroacoustic devices, and direct acoustic stimulators. Individuals with sensorineural hearing loss do not benefit adequately from hearing prostheses that generate mechanical movement of cochlear fluid. Thus, these ...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61M5/142A61M31/00A61B5/00A61N1/36A61N1/05
CPCA61M5/172A61M39/0208A61M39/0247A61M39/04A61M2039/0205A61M2205/3553A61M2205/3561A61M2205/3569A61M2205/3576A61M2205/50A61M2205/52A61M2205/581A61M2205/583A61M2210/0662A61M5/14276A61M5/14244A61M2205/055A61M2230/08
Inventor J·M·希斯曼J·R·詹森
Owner COCHLEAR LIMITED
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