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Preparation method of bacteriostatic gel

A gel and backup technology, applied in the field of preparation of antibacterial gel, can solve the problems of high price, cure the symptoms but not the root cause, and inaccurate curative effect, and achieve the effect of convenient preparation

Inactive Publication Date: 2020-11-06
西安浩然药业有限责任公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

In terms of prevention of gynecological inflammation in traditional Chinese medicine, the method of using traditional Chinese medicine to clean the vulva can be adopted. Some traditional Chinese medicine compound preparations for cleaning the vulva that are currently on the market, some of which treat the symptoms but not the root cause, some use expensive ingredients, and some are in the development process due to inaccurate curative effects. while interrupting development

Method used

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  • Preparation method of bacteriostatic gel

Examples

Experimental program
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Effect test

Embodiment 1

[0016] A preparation method of antibacterial gel, specifically comprising the following steps:

[0017] 1) Weigh 200g Sophora flavescens, 180g Cortex Phellodendri, 180g Cnidium Fructus, 80g Safflower, 50g Peppermint, wash and set aside;

[0018] 2) Ointment preparation: put the flavescens, phellodendron, cnidium, safflower, and mint in 5520 g of purified water after washing in step 1) and decoct once, and then filter for 1.5 hours to obtain a filtrate and filter residue , add 4140g of purified water to the filter residue for secondary decoction, filter the secondary filtrate after the secondary decoction treatment for 1 hour, mix the primary filtrate and secondary filtrate, heat and concentrate at 60°C to 160g extract;

[0019] 3) Take 3g of ethylparaben, add ethanol to it to dissolve it, and obtain ethylparaben solution for subsequent use;

[0020] 4) Take 0.3 g of polyhexamethylene biguanide, add purified water to it to dissolve it, and obtain a polyhexamethylene biguanide ...

Embodiment 2

[0025] A preparation method of antibacterial gel, specifically comprising the following steps:

[0026] 1) Weigh 200g Sophora flavescens, 180g Cortex Phellodendri, 180g Cnidium Fructus, 80g Safflower, 50g Peppermint, wash and set aside;

[0027] 2) Ointment preparation: put the flavescens, phellodendron, cnidium, safflower, and mint in 5520 g of purified water after washing in step 1) and decoct once, and then filter for 1.5 hours to obtain a filtrate and filter residue , add 4140g of purified water to the filter residue for secondary decoction, filter the secondary filtrate after the secondary decoction treatment for 1 hour, mix the primary filtrate and secondary filtrate, heat and concentrate at 60°C to 160g extract;

[0028] 3) Take 3g of ethylparaben, add ethanol to it to dissolve it, and obtain ethylparaben solution for subsequent use;

[0029] 4) Take 0.3 g of polyhexamethylene biguanide, add purified water to it to dissolve it, and obtain a polyhexamethylene biguanide ...

Embodiment 3

[0034] A preparation method of antibacterial gel, specifically comprising the following steps:

[0035] 1) Weigh 200g Sophora flavescens, 180g Cortex Phellodendri, 180g Cnidium Fructus, 80g Safflower, 50g Peppermint, wash and set aside;

[0036] 2) Ointment preparation: put the flavescens, phellodendron, cnidium, safflower, and mint in 5520 g of purified water after washing in step 1) and decoct once, and then filter for 1.5 hours to obtain a filtrate and filter residue , add 4140g of purified water to the filter residue for secondary decoction, filter the secondary filtrate after the secondary decoction treatment for 1 hour, mix the primary filtrate and secondary filtrate, heat and concentrate at 60°C to 160g extract;

[0037] 3) Take 3g of ethylparaben, add ethanol to it to dissolve it, and obtain ethylparaben solution for subsequent use;

[0038] 4) Take 0.3 g of polyhexamethylene biguanide, add purified water to it to dissolve it, and obtain a polyhexamethylene biguanide ...

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Abstract

The invention relates to a preparation method of bacteriostatic gel. The preparation method specifically comprises the following steps of 1) weighing 200g of radix sophorae flavescentis, 180g of cortex phellodendri, 180g of fructus cnidii, 80g of flos carthami and 50g of herba menthae, and cleaning for later use; 2) paste preparation; 3) taking 3g of ethylparaben, and adding ethanol into the ethylparaben to dissolve the ethylparaben to obtain an ethylparaben solution for later use; 4) taking 0.3 g of polyhexamethylene biguanide, and adding purified water into the polyhexamethylene biguanide todissolve the polyhexamethylene biguanide to obtain a polyhexamethylene biguanide solution for later use; 5) taking 20g of carbomer, adding purified water into the carbomer, and soaking for 24 hours until the carbomer is fully swollen to obtain a gel matrix for later use; 6) burdening; and 7) filling, packaging, checking and putting in storage. The preparation method has the advantages that the bacteriostatic gel is convenient to prepare, the average antibacterial rate of the bacteriostatic gel for staphylococcus aureus, candida albicans and escherichia coli is 50% or above, and the bacteriostatic gel has a remarkable effect on diseases such as pruritus vulvae, waist and abdomen pain, abnormal leucorrhea, vaginitis, vulvitis, pelvic inflammation, salpingitis and the like.

Description

technical field [0001] The invention relates to a preparation method of antibacterial gel. Background technique [0002] Gynecological inflammation mainly refers to the acute or chronic inflammation of female reproductive organs after being invaded and infected by various pathogenic bacteria. If the inflammation is not treated in time, it may cause inflammation to spread and cross infection in various physiological parts, and it will bring many complications. Such as gynecological tumors and infertility. Gynecological inflammation mainly includes: vaginitis, vulvitis, pelvic inflammatory disease, salpingitis, etc. In terms of prevention of gynecological inflammation in traditional Chinese medicine, the method of using traditional Chinese medicine to clean the vulva can be adopted. Some traditional Chinese medicine compound preparations for cleaning the vulva that are currently on the market, some of which treat the symptoms but not the root cause, some use expensive ingredi...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/756A61K9/06A61K47/32A61K47/14A61K47/46A61P15/00A61P15/02A61P29/00A61P31/04A61P31/10
CPCA61K9/0034A61K9/06A61K36/234A61K36/286A61K36/489A61K36/534A61K36/756A61K47/14A61K47/32A61K47/46A61K2236/331A61K2236/39A61P15/00A61P15/02A61P29/00A61P31/04A61P31/10A61K2300/00Y02A50/30
Inventor 马少辉
Owner 西安浩然药业有限责任公司
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