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Preparation method of pellet granules for conditioning blood stasis constitution

A technology of micropills and granules, which is applied in the field of preparation of micropills, can solve the problems of blood stasis, physical conditioning, poor stability, and unsatisfactory effects, and achieve the effect of alleviating subcutaneous bleeding and good damp heat stability

Inactive Publication Date: 2021-02-12
河南五极中医药研究院
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] The existing medicines and foods for blood stasis constitution are not effective. Most patients only seek medical treatment after blood stasis worsens. The effect is not ideal, and the drug is easy to relapse after taking a period of time, and long-term use of drug treatment may have toxic side effects
[0004] At present, the commonly used traditional Chinese medicine health products are mostly oral liquids, pills or granules. Compared with pills and granules, oral liquids are more inconvenient to carry. Pills and granules are less stable to heat and water, and commonly used honeyed pills have large dosage Disadvantages such as thick and large appearance

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0030] This example provides a micropellet granule for regulating blood stasis constitution, which comprises the following active ingredients of traditional Chinese medicine in parts by weight: 10 parts of snow lotus culture, 10 parts of peach kernel, 15 parts of hawthorn and 5 parts of rose.

[0031] The preparation method comprises steps:

[0032] (1) Extract the processed or pretreated snow lotus culture, peach kernel, hawthorn and rose respectively to obtain the extract, wherein the peach kernel is extracted twice by heating and refluxing with 8 times the amount of 80% (v / v), and then Remove the ethanol from the filter residue and put it into the Saussurea chinensis culture, hawthorn and rose, add 8 times the amount of the total amount of medicinal materials and decoct twice for 2 hours each time, filter, combine the decoction, and concentrate under reduced pressure to a solid content of 16 % clear ointment;

[0033] (2) Mix clear cream and microcrystalline cellulose acco...

Embodiment 2

[0037] This example provides a micropellet granule for regulating blood stasis constitution, which includes the following active ingredients of traditional Chinese medicine in parts by weight: 15 parts of snow lotus culture, 15 parts of peach kernel, 20 parts of hawthorn and 8 parts of rose.

[0038] The preparation method comprises steps:

[0039] (1) Extract the processed or pretreated snow lotus culture, peach kernel, hawthorn and rose respectively to obtain the extract, wherein the peach kernel is extracted twice by heating and refluxing with 8 times the amount of 80% (v / v), and then Remove the ethanol from the filter residue and put it into the Saussurea chinensis culture, hawthorn and rose, add 8 times the amount of the total amount of medicinal materials and decoct twice for 2 hours each time, filter, combine the decoction, and concentrate under reduced pressure to a solid content of 16 % clear ointment;

[0040] (2) Mix the clear paste and microcrystalline cellulose a...

Embodiment 3

[0044] This embodiment provides a kind of micropellet granule for regulating blood stasis constitution, and its difference with embodiment 1 is that it includes the active ingredients of the following traditional Chinese medicine in parts by weight: 15 parts of snow lotus culture, 10 parts of peach kernel, 20 parts of hawthorn and 8 servings of roses.

[0045] The preparation method comprises steps:

[0046] (1) Superfinely pulverize the processed or pretreated snow lotus culture, peach kernels, hawthorn and roses into powders with a particle size below 75 μm;

[0047] (2) Mix the powder and microcrystalline cellulose according to the weight ratio of 3:2, use acrylic resin 75% ethanol as a wetting agent, add it to a boiling granulator to prepare a soft material, and start granulation to obtain a pellet core The particle size is 60 mesh to 120 mesh; when boiling granulation, set the inlet air temperature at 50-160°C, start granulation, control the material temperature at 40-11...

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Abstract

The invention discloses a preparation method of pellet granules for conditioning blood stasis constitution. The pellet granules comprise the following traditional Chinese medicine active ingredients in parts by weight, 5-20 parts of a saussurea involucrata culture, 5-20 parts of peach kernels, 10-35 parts of haws and 2-10 parts of roses. The preparation method of the pellet granules comprises thefollowing steps of respectively extracting the saussurea involucrata culture, the peach kernel, the hawthorn and the rose to obtain an extract, or crushing the extract into powder, and then preparingthe extract or the powder into the pellet granules. The method is advantaged in that the pellet granules disclosed by the invention are prepared from medicinal and edible medicinal materials, have noside effects, can effectively relieve adverse symptoms such as subcutaneous hemorrhage, rough and dry skin, dark complexion or pigmentation, yellowish-brown plaques and frequent dark eye sockets of patients with blood stasis constitution, and can also be used for daily prevention or conditioning of symptoms of patients with blood stasis constitution which are not serious.

Description

technical field [0001] The invention belongs to the field of traditional Chinese medicine, and in particular relates to a method for preparing pellets for improving blood stasis constitution. Background technique [0002] Blood stasis, one of the dialectics in traditional Chinese medicine, can be caused by cold coagulation, qi deficiency, etc. Blood stasis means that the blood circulation in the body is not smooth, and its operation is blocked, stagnating in the veins or organs. If the blood stasis is in the meridians, it will cause local pain, and if the blood stasis is in the viscera, there will be lumps and tumors. For qi stagnation and blood stasis, traditional Chinese medicine believes that it is a symptom of blood stasis due to stagnation of qi activity, which is mostly caused by emotional discomfort or long-term stagnation of liver qi caused by external evils. People with blood stasis constitution are prone to forgetfulness, memory loss, and often have symptoms such ...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/738A61K9/16A61K9/50A61P7/00A61P29/00A61P7/04A61P17/00A61P27/02A61P1/14A61P7/06
CPCA61K9/1652A61K9/1682A61K9/5047A61K9/5089A61K36/285A61K36/734A61K36/736A61K36/738A61P1/14A61P7/00A61P7/04A61P7/06A61P17/00A61P27/02A61P29/00A61K2300/00
Inventor 叶金承
Owner 河南五极中医药研究院
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