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Amomum tsao-ko and artemisia kuekui mosquito repellent and preparation method of amomum tsao-ko and artemisia kuekui mosquito repellent

A technology of mosquito repellent water and Artemisia tsaokui, which is applied in the field of mosquito repellent water and its preparation, can solve the problems of weak cognitive function, harmfulness of DEET to human body, and use restrictions, and achieve strong permeability, Mosquito repellent and itching-relieving effect with few side effects

Pending Publication Date: 2021-03-02
AGRI PRODS PROCESSING RES INST CHINESE ACAD OF TROPICAL AGRI SCI
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] In addition, DEET is harmful to the human body and may cause insomnia, restlessness, cognitive decline and other phenomena. The scientific community has always questioned the safety of this mosquito repellent ingredient. There are restrictions on the use of this ingredient in

Method used

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  • Amomum tsao-ko and artemisia kuekui mosquito repellent and preparation method of amomum tsao-ko and artemisia kuekui mosquito repellent
  • Amomum tsao-ko and artemisia kuekui mosquito repellent and preparation method of amomum tsao-ko and artemisia kuekui mosquito repellent
  • Amomum tsao-ko and artemisia kuekui mosquito repellent and preparation method of amomum tsao-ko and artemisia kuekui mosquito repellent

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0042]A kind of preparation method of tsaoguo Kuipao mosquito repellent water, comprises the steps:

[0043] (1) Tsaoko and Kuihao leaves were removed from impurities, then vacuum freeze-dried at -70°C for 40 hours, and then powdered with a high-speed pulverizer; then Caoguo and Kuihao leaves were placed in supercritical CO 2 Fluid extraction equipment extraction, the extraction temperature is 35°C, the extraction pressure is 55Mpa, after 3.5 hours of extraction, high-purity Tsaoguo essential oil and Kui Artemisia essential oil are obtained;

[0044] (2) Accurately weigh a certain amount of vacuum-freeze-dried Artemisia annua leaf powder, add 95% ethanol with 20 times the liquid-to-material ratio (mL / g) and extract for the first time at 30°C and 10kPa pressure for 30min, then filter it through gauze Residue, the resulting filter residue was extracted again with 20 times of 95% ethanol at a temperature of 30°C and a pressure of 10kPa for 30min, then filtered through gauze to re...

Embodiment 2

[0049] A kind of preparation method of tsaoguo Kuipao mosquito repellent water, comprises the steps:

[0050] (1) After removing impurities, Caoguo and Kuihao leaves were vacuum freeze-dried at -80°C for 30 hours, and then crushed into powder with a high-speed pulverizer; then Caoguo and Kuihao leaves were placed in supercritical CO 2 Fluid extraction equipment extraction, the extraction temperature is 38°C, the extraction pressure is 58Mpa, after 3 hours of extraction, high-purity Tsaoguo essential oil and Kui Artemisia essential oil are obtained;

[0051] (2) Accurately weigh a certain amount of vacuum freeze-dried Artemisia annua leaf powder, add 95% ethanol with a liquid-to-material ratio (mL / g) of 30 times, extract for the first time at a temperature of 40°C and a pressure of 20kPa for 40min, and then filter through gauze Residue, the resulting filter residue was extracted again with 30 times of 95% ethanol at a temperature of 40°C and a pressure of 20kPa for 40min, then ...

Embodiment 3

[0056] A kind of preparation method of tsaoguo Kuipao mosquito repellent water, comprises the steps:

[0057] (1) After removing impurities, Caoguo and Kuihao leaves were vacuum freeze-dried at -78°C for 32 hours, and then crushed into powder with a high-speed pulverizer; then Caoguo and Kuihao leaves were placed in supercritical CO 2 Fluid extraction equipment for extraction, the extraction temperature is 40°C, the extraction pressure is 50Mpa, after 3.5 hours of extraction, high-purity Tsaoguo essential oil and Kui Wo essential oil are obtained;

[0058] (2) Accurately weigh a certain amount of vacuum-freeze-dried Artemisia annua leaf powder, add 95% ethanol with 40 times the liquid-to-material ratio (mL / g) to extract for the first time at 32°C and 15kPa pressure for 60min, then filter it through gauze residue, the resulting filter residue was extracted again with 40 times of 95% ethanol at a temperature of 32°C and a pressure of 15kPa for 60min, then filtered through gauze ...

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Abstract

The invention discloses amomum tsao-ko and artemisia kuekui mosquito repellent and a preparation method thereof, and belongs to the field of daily chemicals. The green and safe mosquito repellent withthe effects of repelling mosquitoes, relieving itching, resisting bacteria, diminishing inflammation, calming, easing pain and the like is prepared by taking the amomum tsao-ko essential oil, the Artemisia kueshanensis essential oil and the Artemisia kueshanensis leaf extracting solution as effective components, the mosquito repellent is specifically prepared from the following raw materials in percentage by mass: 1%-3% of amomum tsao-ko essential oil, 1%-3% of artemisia kueshanensis essential oil, 10%-20% of artemisia kueshanensis leaf extracting solution, 50%-75% of 95% ethanol, 1%-2% of filter aid and the balance of deionized water. The prepared amomum tsao-ko and artemisia kuekui mosquito repellent has a certain relieving effect on red and swollen skin, pruritus and pain caused by mosquito bite, also has antibacterial and anti-inflammatory effects on bite wounds, can promote wound healing and skin regeneration, and is suitable for market popularization and application.

Description

technical field [0001] The invention belongs to the technical field of daily-use chemicals, and in particular relates to a mosquito repellent water of Artemisia tsaoguo and a preparation method thereof. Background technique [0002] At present, the main ingredients of mosquito repellent water are DEET and alcohol, as long as they are applied to the surface of human skin, they can have the effect of repelling mosquitoes. Among them, DEET, the main component of mosquito repellent water, is a widely used insecticide. Although DEET can work by blocking insect olfactory receptors, making insects lose their sense of special smells from humans or animals, spraying it on the skin or clothing can prevent insect bites, but products containing DEET Do not come into direct contact with broken skin or use under clothing. As an irritant, DEET is unavoidable for skin irritation. [0003] In addition, DEET is harmful to the human body and may cause insomnia, restlessness, cognitive decli...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K8/92A61K8/9789A61Q17/02A61Q17/00A61P17/00A61P29/00A61P17/04A61P17/02A61P31/02
CPCA61K8/922A61K8/9789A61Q17/02A61Q17/005A61P17/00A61P29/00A61P17/04A61P17/02A61P31/02A61K2800/592A61K2800/5922
Inventor 李积华付调坤周伟廖良坤
Owner AGRI PRODS PROCESSING RES INST CHINESE ACAD OF TROPICAL AGRI SCI
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