Novel hydrocolloid acne patch for treating acne

A hydrocolloid, acne technology, applied in medical preparations containing active ingredients, medical raw materials derived from ferns/filamentous plants, plant raw materials, etc., can solve the problem of poor recovery effect of acne parts and poor skin smoothness. High, affect the aesthetics and other issues, to achieve good antibacterial effect, good therapeutic effect, smoothness improvement effect

Inactive Publication Date: 2021-03-09
JIANGSU NEWVALUE MEDICAL PROD CO LTD +1
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] However, the antibacterial effect of the existing acne patches is not ideal, and it is easy to make the skin at the acne site inflamed, the recovery effect of the acne site is poor, and the acne scars are more obvious, so that the smoothness of the skin after treatment is not high, which affects the appearance.

Method used

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  • Novel hydrocolloid acne patch for treating acne
  • Novel hydrocolloid acne patch for treating acne
  • Novel hydrocolloid acne patch for treating acne

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1-7

[0012] Embodiment 1-7, as shown in table 1

[0013] Table 1 Example 1-7

[0014]

[0015]

Embodiment 8

[0025] Embodiment 8 antibacterial performance evaluation

[0026] The test bacteria used is Bacillus acnes, a common bacteria that causes acne. Use an inoculation loop to gently draw a circle of Bacillus acnes colonies into 100mL nutrient broth, and culture on a constant temperature shaker at 37°C at 150rpm Prepare physiological saline to dilute the bacterial suspension to 3.0X 106CFU / mL for antibacterial testing. The hydrocolloid acne patch prepared in the above example was leached with purified water for 24 hours, the leaching ratio water:sample=10:1, and the leaching solution was used as the sample to be tested. Purified water was used as a blank experiment, and the commercially available Meirokang Acne Patch was used as a comparative experiment. Take 1ML of the bacterial suspension and add it to the above-mentioned sample solution to be tested, place it on a constant temperature shaker at 37°C and incubate at 150rpm for 1h, take 1mL of the solution for counting viable b...

Embodiment 9

[0029] Example 9 Acne Removal and Anti-inflammatory Effect Evaluation

[0030] The age of the test population: 220 patients with acne, including 110 males and 110 females.

[0031] Test plan: Divide 220 subjects into 11 groups, and give the hydrocolloid acne patch made of Examples 1-7 and Comparative Example 1-3 and the commercially available similar product Meiruokangjing acne patch respectively. Visually observe the acne-removing effect before and after the test and record the phenomenon. Separately test and record each indicator, as well as the volunteers' feelings of use, and make a comprehensive evaluation.

[0032] How to use: According to the method of using the hydrocolloid adhesive patch, remove the package, take it out, remove the protective layer, choose a patch with a suitable size, and gently stick the patch on the designated part of the tester. The use time is one month. Use it every morning and evening after cleansing the skin. Apply it to the acne-prone area....

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Abstract

The invention discloses a novel hydrocolloid acne patch for treating acne. A layer of self-adhesive hydrocolloid matrix is attached to an outer layer base material of the acne patch, the matrix is covered with a removable protective layer, the hydrocolloid acne patch contains resurrection grass and quaternary ammonium salt 73, and the resurrection grass is one or more of selaginella tamariscina extract, Boehmeria albiflora leaf extract and Pholiota chevalieri extract. The hydrocolloid matrix further contains 15-60wt% of adhesive substrate, 5-35wt% of rubber elastomer, 5-60wt% of hydrophilic polymer and 0-40wt% of tackifying resin. The novel hydrocolloid acne patch for treating acne contains the quaternary ammonium salt 73 and the resurrection grass, can promote wound healing, has the effect of inhibiting acne bacillus, has remarkable acne removal and inflammation diminishing effects and has an obvious improvement effect on skin smoothness.

Description

technical field [0001] The invention belongs to the field of acne treatment, and more specifically relates to a novel hydrocolloid acne patch for treating acne. Background technique [0002] Acne patch is a special hydrophilic hydrocolloid patch for acne treatment. It can absorb secretions after being pasted on acne and help to calm acne. And it can reduce the chance of bacterial infection, which is more suitable for inflammatory acne. [0003] However, the antibacterial effect of the existing acne patches is not ideal, and the skin at the acne site is easily inflamed, the recovery effect of the acne site is poor, and the acne scars are more obvious, so that the smoothness of the skin after treatment is not high, which affects the appearance. Contents of the invention [0004] The object of the present invention is to provide a novel hydrocolloid acne patch for treating acne, so as to solve the problems raised in the above-mentioned background technology. [0005] In ord...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/11A61K36/185A61K36/41A61K9/70A61P17/10A61P31/02A61P31/04A61P29/00A61K31/14
CPCA61K9/7053A61K31/14A61K36/11A61K36/185A61K36/41A61P17/10A61P29/00A61P31/02A61P31/04A61K2300/00
Inventor 龚祖光孙萍褚鹏
Owner JIANGSU NEWVALUE MEDICAL PROD CO LTD
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