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Application of anhydroicaritin to preparation of medicine for treating psoriasis

A technology of icariin and psoriasis, which is applied in the field of medicine, can solve the problems of difficult treatment of psoriasis, and achieve the effect of improving treatment effect and quality of life, better effect and symptom improvement

Pending Publication Date: 2021-05-11
LUNAN PHARMA GROUP CORPORATION
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0012] In order to solve the problem that psoriasis is difficult to treat in the prior art, the present inventor has found the significant curative effect of icariin in the treatment of psoriasis through long-term in-depth research, thus completing the present invention

Method used

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  • Application of anhydroicaritin to preparation of medicine for treating psoriasis
  • Application of anhydroicaritin to preparation of medicine for treating psoriasis
  • Application of anhydroicaritin to preparation of medicine for treating psoriasis

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0025] Embodiment 1 icarigenin injection

[0026]

[0027] Preparation process: mix the prescribed amount of propylene glycol and ethanol evenly, add icariin, stir to dissolve, add the prescribed amount of 0.9% sodium chloride solution, stir evenly, add 0.5% activated carbon for needles, stir, decarbonize, that is have to.

Embodiment 2

[0028] Example 2 Icarigenin Injection

[0029]

[0030] Preparation process: Add icariin to the prescribed amount of PEG-400, stir to dissolve, add 0.9% sodium chloride solution to 10L, stir evenly, add 0.5% activated carbon for needles, stir, decarbonize, and obtain.

Embodiment 3

[0031] Example 3 Icarigenin Injection

[0032]

[0033] Preparation process: Mix the prescribed amount of ethanol and Tween-80 evenly, add icariin, stir to dissolve, add water for injection to 10L, stir evenly, add 0.5% activated carbon for needles, stir, decarbonize, and get ready.

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PUM

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Abstract

The invention belongs to the field of medicine, and particularly relates to application of anhydroicaritin, namely the application of the anhydroicaritin to preparation of a medicine for treating psoriasis. Animal tests show that the anhydroicaritin has a significant prevention and treatment effect on the psoriasis, can significantly improve psoriasis area and severity index (PASI) score and tissue morphological change of skin lesions of psoriasis, which proves that the anhydroicaritin has the application of treating the psoriasis. Compared with an existing medicine and method for treating the psoriasis, the novel application method disclosed by the invention can get an unexpected curative effect, the cure rate is high, and the novel application method is an innovation for treating the psoriasis.

Description

technical field [0001] The invention belongs to the field of medicine, and relates to a medical application of icariin, in particular to the medical application of icariin in the preparation of medicines for treating psoriasis. Background technique [0002] Psoriasis is a common chronic relapsing inflammatory skin disease. The course of the disease is relatively long, and it cannot be completely cured at present. As an erythematosquamous skin disease, it often causes damage to the appearance of patients, and seriously affects the quality of life and even physical and mental health of patients. In the late stage of the disease, it is very likely to damage the patient's joints and multiple internal organs, posing a great threat to the life and health of the patient. [0003] The current literature shows that the etiology of psoriasis is still unclear, and it is generally considered to be mainly mediated by immunity, which is an "autoimmune system disorder disease". Most sch...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K31/352A61P17/06A61N5/06
CPCA61K31/352A61P17/06A61N5/0616A61N2005/0661
Inventor 姚景春吕金钢
Owner LUNAN PHARMA GROUP CORPORATION
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