Efficient dioxin sample purification and separation column suitable for mass spectrometry

Abstract

The invention discloses an efficient dioxin sample purification and separation column suitable for mass spectrometry. The efficient dioxin sample purification and separation column comprises an acid column, a composite column and a carbon column. The filler of the acid column sequentially comprises neutral silica gel, 44% acidic silica gel, 22% acidic silica gel, neutral silica gel and anhydrous sodium sulfate from bottom to top; the filler of the composite column sequentially comprises neutral silica gel, alkaline silica gel, neutral silica gel, 22% acidic silica gel, neutral silica gel and anhydrous sodium sulfate from bottom to top; the filler of the carbon column sequentially comprises activated carbon powder and anhydrous sodium sulfate from bottom to top; the dioxin sample sequentially passes through an acid column, a composite column and a carbon column to be subjected to purification pretreatment, and finally a polychlorinated biphenyl and dioxin sample is obtained. The pretreatment column combination provided by the invention can meet the pretreatment of dioxin and dioxin polychlorinated biphenyl in samples of different types of feeds and livestock and poultry products.

Description

technical field [0001] The invention relates to the fields of chemical analysis and biological research, in particular to a dioxin high-efficiency sample purification separation column suitable for mass spectrometry. Background technique [0002] Environmental pollution has become a social hot spot that the public and the government pay attention to. Persistent organic pollutants (POPs) represented by dioxins have received special attention. These compounds have characteristics such as persistence, long-distance migration, and bioaccumulation. They are widely distributed around the world and are important pollutants that affect human health. risk. [0003] Dioxins are a class of compounds with strong carcinogenic, teratogenic and mutagenic effects. They are highly toxic (the International Center for Cancer Research lists them as Class I human carcinogens), and are difficult to degrade and can accumulate in the body. . Generally, dioxins refer to structurally and chemicall...

AI Technical Summary

Problems solved by technology

This method is suitable for the detection of environmental and biological samples such as sediment, soil, atmosphere, bark, etc. It is not effective for the removal of impurities in different media such as feed, livestock and poultry products, and samples containing more fat

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