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GC method for detecting residual quantity of solvent in compound

The invention discloses a method for analyzing a residual quantity of a solvent in a compound by GC (Gas Chromatograph). The method comprises the step of carrying out separation by adopting the following chromatographic conditions: a detector is a hydrogen flame ionization detector, the temperature of the detector is 200 DEG C to 300 DEG C and is preferably 300 DEG C, and the temperature of an injection opening is 180 DEG C to 250 DEG C and is preferably 220 DEG C; a chromatographic column is a medium-polarity capillary gas chromatography column and adopts a programmed temperature process of keeping the temperature of 40 to 60 DEG C for 3 to 10min, then heating to the temperature of 100 to 140 DEG C at a speed of 5 to 15 DEG C/min, keeping the temperature of 100 to 140 DEG C for 1 to 10min, heating to the temperature of 200 to 230 DEG C at a speed of 15 to 25 DEG C/min and keeping the temperature of 200 to 230 DEG C for 1 to 20min; carrier gas is nitrogen, hydrogen or argon and is preferably nitrogen, and the flow rate of the carrier gas is 1ml/min to 10ml/min and is preferably 3ml/min; the solvent is selected from one or more of C1 to C6 carboxylic acid, methanol, ethanol, acetonitrile, ethyl acetate, tetrahydrofuran, methylbenzene and N,N-dimethylformamide; the C1 to C6 carboxylic acid is preferably C1 to C4 carboxylic acid and is more preferably acetic acid. When the method is adopted to detect the residual quantity of the solvent, the operation is simplified, time is saved and cost is saved.
Owner:NEW FOUNDER HLDG DEV LLC +2
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