7 results about "Bioaccumulation" patented technology

Systems and methods are provided for comprehensive in vivo nanotoxicity testing, as well as fabrication methods of chips used for nanotoxicity testing. A three-dimensional (3D)-printed, automated microfluidic chip can be configured for in vivo nanotoxicity testing, and the chip can allow for multi-route (e.g., waterborne and / or foodborne) exposure of marine organisms to small materials (e.g., plastics such as microplastics and / or nanoplastics (NPLs), or metals), providing real-time, in situ monitoring of bioaccumulation and oxygen consumption.

Disclosed are methods for remediating soil having persistent and bioaccumulative contaminants, and more particularly, methods for remediating soil having perfluoro and polyfluoroalkyl substances (PFAS) and other halogen-containing contaminants by rapid electrothermal mineralization.

This application relates to the technical field of environmental monitoring and data analysis, and particularly to a screening method for priority-controlled OPEs based on surface water concentration data. According to the organophosphate ester flame retardants (OPEs) exposure database, the monitoring data of each OPE compound within a specified time period is obtained. For each OPE compound, based on the monitoring data, the quantitative data of environmental persistence, bioaccumulation, and toxicity effects are respectively obtained, and the exposure potential index and hazard potential index are obtained through principal component analysis; the exposure potential index and hazard potential index are processed to obtain the priority control index; based on the priority control index, sorting is carried out to screen OPE compounds that meet the preset conditions, and the screening results are determined as the priority control targets. This application can simultaneously identify key pollutants with high exposure risks and high hazard risks, reveal the main risk drivers of different OPEs, and effectively support the screening and priority control decision-making of emerging pollutants.

This invention discloses a chromium (VI)-resistant Enterococcus faecium, its isolation method, and its applications in the field of microbial technology. This chromium (VI)-resistant Enterococcus faecium, classified and named Enterococcus faecium, was deposited on October 24, 2025, at the China General Microbiological Culture Collection Center (CGMCC), with accession number CGMCC NO.36330. The chromium (VI)-resistant Enterococcus faecium isolated by this invention can survive in high-concentration chromium (VI) environments and has a strong adsorption effect on hexavalent chromium, reducing the residue and bioaccumulation of hexavalent chromium in feed, thereby mitigating its toxicity to poultry.

This invention discloses a four-dimensional Raman monitoring system and dynamic quantitative method for environmental microplastics in vivo, belonging to the field of environmental ecological monitoring and analysis technology. The system includes a confocal spectroscopy acquisition module, a controller, and a data processing module. It acquires the three-dimensional coordinates of live samples through coordinated spatial scanning and simultaneously acquires Raman signals to construct four-dimensional spectral data. A multidimensional convolutional instance segmentation network is used to process the four-dimensional Raman spectral data, identifying and classifying endogenous biological matrices and exogenous multi-mixed microplastics in vivo, outputting voxel-level semantic classification results, and then quantitatively calculating the absolute retention volume and abundance of microplastics in the organism. This invention overcomes the shortcomings of existing technologies in label-free quantification under complex biological backgrounds, achieving in-situ accurate identification of mixed microplastics in vivo, and providing a standardized quantitative monitoring method for assessing the bioaccumulation, metabolic patterns, and ecotoxicological effects of environmental microplastics.

This invention relates to a miniature flexible temperature sensor for use in living organisms, its fabrication method, and its applications. The miniature flexible temperature sensor comprises a thermosensitive conductive layer polymerized in situ from acrylamide, glycerol, choline chloride, and lipoic acid, and a flexible encapsulation layer made of a flexible biocompatible material. The fabrication method includes mixing acrylamide, glycerol, and choline chloride to obtain a deep eutectic solvent; adding lipoic acid to the deep eutectic solvent to obtain a homogeneous solution; injecting the homogeneous solution into a mold made of the flexible biocompatible material to obtain a material to be cured; and subjecting the material to be cured to ultraviolet light curing to obtain the miniature flexible temperature sensor. Its advantages include good biocompatibility, reducing the potential bioaccumulation risk of traditional conductive polymers or nanomaterials; high sensitivity, good repeatability, linearity, and resolution; a thermosensitive layer thickness of 1–2 mm, suitable for non-invasive monitoring on the body surface and multi-point temperature detection in confined biological spaces; and a simple fabrication method with no leakage risk.

This invention belongs to the field of environmental and human health technology, and discloses a PM... 2.5 An alveolar microresponsive system carrying insoluble particles and a model for evaluating its relative bioefficacy. This alveolar microresponsive system establishes an alveolar microresponsive system by carrying insoluble PM... 2.5 A model for the bioaccumulation and relative bioavailability of -M, derived from lung surfactant extraction and PM2.5. 2.5 The process of incubating and extracting adsorbed substances from M, screening adsorbent layer lipids and proteomes, and assembling microreaction system models revealed the properties of water-insoluble PM. 2.5 The accumulation and absorption characteristics of PM2.5 particles in the alveoli; lipidomics and proteomics analyses clarified the composition of insoluble PM2.5 particles in the alveoli. 2.5 A degradation and transformation microreaction system consisting of -M and alveolar fluid was constructed, and a non-water-soluble PM2.5 was first constructed based on the microreaction system. 2.5 - Model for calculating alveolar turnover rate after M respiratory exposure and the amount of water-insoluble PM in alveoli 2.5 -M bioefficacy assessment model.