A Method for Quantifying the Similarity Between Biological Evolutionary Trees

A technique for biological evolution, quantitative methods, applied in the fields of bioinformatics and evolutionary biology research

Active Publication Date: 2021-11-05
HUAINAN NORMAL UNIV
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  • Abstract
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Problems solved by technology

[0004] However, as far as we know, there is still no calculation method or software for horizontally comparing the similarity of two evolutionary trees

Method used

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  • A Method for Quantifying the Similarity Between Biological Evolutionary Trees

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Embodiment

[0052] For two evolutionary trees, this embodiment will introduce in detail the analysis and calculation of three similarity measurement indicators using this method, and the specific details are as follows:

[0053] (1) Obtain evolutionary tree data

[0054] The data involved in this patent can be obtained in two ways: ① self-constructed by different methods to obtain two evolutionary trees containing the same species; ② artificial information extraction from the evolutionary tree diagrams in published academic papers in the field of evolutionary biology research.

[0055] (2) Data preprocessing

[0056] According to the tree relationship and species information of the evolutionary tree, the evolutionary tree to be compared was transformed into newick format, and then the subsequent analysis was carried out according to the species relationship and species name in this format. This embodiment takes figure 1 Take the two evolutionary trees i and j in the example as an exampl...

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Abstract

The invention discloses a new algorithm for quantifying the similarity between biological evolutionary trees. In the field of bioinformatics and evolutionary biology. According to the measurement method steps and implementation schemes of the similarity between biological evolutionary trees in the present invention, a method for specifically calculating the similarity of biological evolutionary trees is proposed, which is the research on the phylogeny and related methods between species of biological evolutionary trees in the field of biology, similar The comparative study between the tree structure diagrams provides a reference.

Description

[0001] 1. Field of invention [0002] The invention belongs to the field of bioinformatics and evolutionary biology research under the biology major, and more specifically relates to an estimation method for measuring the similarity between biological evolutionary trees. 2. Background technology [0003] Since the 20th century, molecular biology has developed rapidly, especially with the extensive application of computer science and biotechnology in biology. Molecular phylogeny in evolutionary biology has also developed rapidly with the accumulation of sequencing technology and biomolecular data. Among them, the construction of biological evolutionary tree (also known as: molecular phylogenetic tree, phylogenetic tree, etc.) is an important means to carry out phylogenetic deduction or phylogenetic relationship research among species. With the continuous invention of methods for constructing and analyzing evolutionary trees, such as maximum likelihood (Maximum likelihood, ML),...

Claims

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Application Information

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Patent Type & AuthorityPatents(China)
IPC IPC(8): G16B10/00G06K9/62
CPCG16B10/00G06F18/22
Inventor张际峰王潇邢应如胡东汪承润毕勇陈晓雪华攀玉朱国华史国经
OwnerHUAINAN NORMAL UNIV