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Neutron diagnosis and treatment device and neutron diagnosis and treatment method based on neutron field measurement inversion

A neutron field, neutron technology, applied in the field of nuclear medicine

Active Publication Date: 2021-07-13
国科中子刀(青岛)医疗科技有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

At present, there is no effective way to realize real-time diagnosis of tumor parameters and optimize neutron therapy without causing additional irradiation of the subject

Method used

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  • Neutron diagnosis and treatment device and neutron diagnosis and treatment method based on neutron field measurement inversion
  • Neutron diagnosis and treatment device and neutron diagnosis and treatment method based on neutron field measurement inversion
  • Neutron diagnosis and treatment device and neutron diagnosis and treatment method based on neutron field measurement inversion

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0050] like figure 1 As shown, a proton accelerator is used to bombard a neutron target as the neutron source 1, and the beam of the proton accelerator bombards the neutron target located below from above to provide a vertical neutron beam.

[0051] The neutron irradiation mechanism 2 is located under the target, wraps the neutron target and the end of the proton accelerator, and is composed of a fast neutron moderator layer, a photon shielding layer, a thermal neutron absorbing layer, and a collimation channel.

[0052] The support of the subject and its driving mechanism are composed of the treatment bed and the support structure of the treatment bed, located directly under the neutron irradiation mechanism 2, and can be adjusted in front, rear, left, and right positions and heights, so that the target area of ​​the subject is directly facing the neutron irradiation mechanism 2 the outgoing neutron beam.

[0053] The neutron imaging detection mechanism 3 is embedded in the ...

Embodiment 2

[0070] A proton accelerator is used to bombard a neutron target as a neutron source 1, and the beam of the proton accelerator bombards the neutron target located on the right from the left to provide a horizontal neutron beam.

[0071] The neutron irradiation mechanism 2 is located on the right side of the target, wraps the neutron target and the end of the proton accelerator, and is composed of a fast neutron moderator layer, a photon shielding layer, a thermal neutron absorbing layer, and a collimation channel.

[0072] The irradiated object support and its driving mechanism are composed of a treatment couch and a treatment couch support structure, located on the right of the neutron irradiation mechanism 2, and can be adjusted in front, rear, left, and right positions and heights, so that the target area of ​​the irradiated object is directly facing the neutron irradiation mechanism 2 the outgoing neutron beam.

[0073] The neutron imaging detection mechanism 3 is located o...

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Abstract

The invention discloses a neutron diagnosis and treatment device and a neutron diagnosis and treatment method based on neutron field measurement inversion, and the neutron diagnosis and treatment device comprises a controller, and a neutron source, a neutron irradiation mechanism, a neutron imaging detection mechanism, an irradiated body positioning mechanism, a targeted drug injection mechanism and a diagnosis and treatment planning mechanism which are electrically connected with the controller. The neutron source is connected with the neutron irradiation mechanism, the neutron irradiation mechanism irradiates neutron beams to an irradiated body, the neutron imaging detection mechanism detects neutron intensity distribution and images on the irradiated body in real time, and the targeted drug injection mechanism injects targeted drugs to the irradiated body. Compared with the prior art, the neutron diagnosis and treatment device and the neutron diagnosis and treatment method based on neutron field measurement inversion have the advantages that by arranging the neutron imaging detection mechanism and the diagnosis and treatment planning mechanism, diagnosis and treatment can be realized at the same time under the condition that the illuminated body is not subjected to extra irradiation, and the treatment scheme is controlled in real time, and accurate neutron treatment of the illuminated body is realized.

Description

technical field [0001] The present invention relates to the field of nuclear medicine. More specifically, the present invention relates to a neutron diagnosis and treatment device and a neutron diagnosis and treatment method based on neutron field measurement inversion. Background technique [0002] Neutron capture therapy is a new type of tumor treatment, which destroys tumor cells through the nuclear reaction between neutrons and pro-tumor targeting drugs (such as boron-containing drugs, gadolinium, etc.). The basic principle of neutron therapy is to first inject the target with pro-tumor targeting drugs. This drug is non-toxic and harmless to the human body, but it has a strong affinity with cancer cells. After entering the human body, the drug and tumor cells quickly Combined with and enriched in tumor cells; then use appropriate neutron rays to irradiate the tumor site of the subject, and the neutrons will undergo a nuclear reaction with the target nuclide enriched in ...

Claims

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Application Information

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IPC IPC(8): A61N5/10
CPCA61N5/10A61N5/103A61N2005/109
Inventor 不公告发明人
Owner 国科中子刀(青岛)医疗科技有限公司
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