Bee venom toothpaste and preparation method of bee venom toothpaste

A toothpaste and bee venom technology, which is applied in the field of bee venom toothpaste and its preparation, can solve the problem of removing components of sensitization reactions, and achieve the effect of mild and safe use, continuous and bactericidal effect, and keeping breath fresh

Active Publication Date: 2021-10-08
广东日和堂医药科技有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] Studies have found that the bee venom extract contains powerful antibacterial active components, but there are other components in the bee venom extract that are likely to cause allergic reactions in the human body, and it is difficult to isolate the components of the bee venom extract that have sensitization reactions. points removed, thus limiting the application of bee venom extract in toothpaste

Method used

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  • Bee venom toothpaste and preparation method of bee venom toothpaste
  • Bee venom toothpaste and preparation method of bee venom toothpaste
  • Bee venom toothpaste and preparation method of bee venom toothpaste

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0066] A bee venom toothpaste, composed of 26kg water, 1kg solubilizer, 30kg humectant, 0.4kg adhesive, 0.5kg foaming agent, 40.45kg friction agent, 0.65kg other additives and 1kg compound antibacterial peptide, each component The input amount is detailed in Table 1.

[0067] Among them, the solubilizer is hydrated silica, the humectant is sorbitol, the adhesive is sodium carboxymethyl cellulose, the foaming agent is sodium lauryl sulfate, the friction agent is calcium carbonate, and other additives are chelating agents , the chelating agent is sodium pyrophosphate.

[0068] The compound antimicrobial peptide is composed of 1kg honeysuckle, 6kg dandelion, 10kg licorice, 10kg honey, 0.01kg bee venom extract and 72.99kg edible oil. The edible oil is rapeseed oil. The preparation method comprises the following steps:

[0069] In step (1), 1 kg of honeysuckle, 6 kg of dandelion, 10 kg of licorice and 72.99 kg of rapeseed oil are mixed and added into a cooking pot, boiled at 70°C ...

Embodiment 2

[0076] The difference from Example 1 is that the preparation method of the compound antimicrobial peptide is different. Specifically, in step (1), 0.5 kg of grain worms, 1 kg of honeysuckle, 6 kg of dandelion, 10 kg of licorice and 72.49 kg of rapeseed oil are added to boil in the pot.

Embodiment 3

[0078] The difference with Example 2 is: the content of each component in the compound antibacterial peptide is different, specifically, the compound antibacterial peptide consists of 3kg honeysuckle, 2kg dandelion, 15kg licorice, 1kg grain worm, 2kg honey, 0.1kg bee venom extract and 76.9 kg edible oil, the edible oil is rapeseed oil.

[0079] The parameters of the preparation method of compound antimicrobial peptides are also different, specifically:

[0080] In step (1), 3 kg of honeysuckle, 2 kg of dandelion, 15 kg of licorice, 1 kg of grain worm and 76.9 kg of rapeseed oil were mixed and added into the cooking pot, boiled at 80°C for 1.5h, filtered to take the filtrate, cooled to 30°C, Get herbal oil.

[0081] In step (2), 2kg of honey, 0.1kg of bee venom extract and the traditional Chinese medicine oil prepared in step (1) were added to the homogenization tank, heated and homogenized at 75°C for 0.5h, then naturally cooled to 26°C, and allowed to stand for 30h. The ope...

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Abstract

The invention relates to the technical field of antibacterial toothpaste, and particularly discloses bee venom toothpaste and a preparation method of the bee venom toothpaste. The bee venom toothpaste is composed of the following components by mass percentage: 0.1%-15% of composite antibacterial peptide, 1%-10% of solubilizer, 10%-36% of humectant, 0.4%-2% of adhesive, 0.5%-5% of foaming agent, 15%-25% of water, 0.65%-4.2% of other auxiliaries and 5%-40% of friction agent; each mass percentage of the composite antibacterial peptide is prepared from the following components in percentage by mass: 1-3% of honeysuckle, 2-6% of dandelion, 10-15% of liquorice, 2-10% of honey, 0.01-0.1% of bee venom extract, 0-1% of grain insects and the balance of edible oil. The bee venom toothpaste prepared by the invention is good in antibacterial effect, safe in components, low in irritation and not easy to cause allergic reaction of a human body.

Description

technical field [0001] The invention relates to the field of antibacterial toothpaste, in particular to a bee venom toothpaste and a preparation method thereof. Background technique [0002] Dental caries and periodontal disease are the main causes of tooth loss in adults and are the most common oral diseases in humans. [0003] Toothpaste is a must for people's daily cleaning. In order to reduce the occurrence of dental caries and periodontal disease and better care for dental health, people usually add active components with antibacterial effects to toothpaste, so that people can clean their mouth while cleaning their teeth daily. bacteria in. [0004] Studies have found that the bee venom extract contains powerful antibacterial active components, but there are other components in the bee venom extract that are likely to cause allergic reactions in the human body, and the existing technology is difficult to isolate the components of the bee venom extract that have sensiti...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K8/9789A61K8/98A61K8/25A61K8/86A61K8/46A61K8/92A61K8/34A61Q11/00A61Q17/00A61P1/02A61P31/02
CPCA61K8/9789A61K8/988A61K8/987A61K8/25A61K8/86A61K8/463A61K8/922A61K8/345A61Q11/00A61Q17/005A61P1/02A61P31/02A61K2800/5922A61K2800/592Y02A50/30
Inventor 陈日和包海玲唐飞
Owner 广东日和堂医药科技有限公司
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