Non-invasive imaging screening and minimally invasive sampling nucleic acid typing combined detection system

Abstract

The invention relates to a non-invasive imaging screening and minimally invasive sampling nucleic acid typing combined detection system. The system comprises a non-invasive telecentric imaging health analysis system and a minimally invasive sampling multi-channel nucleic acid amplification parallel detection system; the non-invasive telecentric imaging health analysis system is configured to shoot a local surface image of the subject and perform machine learning and clustering analysis on the shot local surface image of the subject to obtain the subject with image feature abnormal change; the minimally invasive sampling multi-channel nucleic acid amplification parallel detection system is configured to perform minimally invasive sampling on a subject with abnormal change of image features, and perform detection and analysis of medical molecular typing indexes or physiological and pathological change indexes on the minimally invasive sampling to obtain specific gene detection results of the typing indexes or the physiological and pathological change indexes. According to the system, artificial intelligence conjoint analysis is carried out by combining detection results of noninvasive telecentric imaging screening and minimally invasive sampling nucleic acid accurate typing, mutual investigation is carried out, the probability of missing detection of a single method is reduced, the accuracy of detection and identification is improved, and the onset risk condition is evaluated or predicted and early-warned.

Description

technical field

[0001] The invention relates to a combined detection system of noninvasive imaging screening and minimally invasive sampling nucleic acid typing, and relates to the technical fields of medical molecular diagnosis and traditional Chinese medicine health analysis. Background technique

[0002] According to the estimates of the International Cancer Research Center (IARC), in 2018, there were 2,093,900 new cases of lung cancer and 1,761,000 new deaths in the world. my country is a big country in cigarette sales, and the incidence and mortality of lung cancer have always been higher than other countries in the world. Studies have found that if the tumor has not spread, the 5-year survival rate can reach 56%, but only 16% of patients can be diagnosed in the early stage; once the tumor spreads and metastasizes, the 5-year survival rate of lung cancer patients is only about 18.6%, more than half of patients die within 1 year of diagnosis. Therefore, to control lung...

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