21 results about "Research center" patented technology

The present application discloses a research HIS system for clinical trials, which relates to the technical field of clinical trials, and includes a research participant management end, including a participant registration module, a pre-screening module, a research participant tracking module, a data collection module, an access rights management module, a research participant communication module, and a participant security and privacy protection module; a planning and scheduling management end, including a test plan module, a research center management module, a personnel task allocation module, a test schedule management module, a task tracking progress monitoring module, a resource scheduling management module, and a visit arrangement reminder module; a collaborative communication end, including a project team collaboration module, an email message notification module, a real-time chat discussion module, a file sharing collaborative editing module, a meeting schedule module, a discussion board knowledge base module, and a task allocation tracking module. The present application has the effect of facilitating the reasonable management and monitoring of clinical data in a hospital information management system.

The embodiment of the invention provides an interface display method, a client side and a middle table component center, the method relates to the technical field of research methods in the technical field of the Internet, and the method comprises the following steps: receiving an access operation executed by a target object for a target page in a target application program; in response to the access operation, sending an investigation request to a middle station component center; the research request is used for requesting to research a target code file of the component; receiving a response message sent by the middle station component center; the response message comprises the target code file, and the target code file comprises an interface logic code; and generating an investigation interface based on the interface logic code, and displaying the investigation interface on the target page. In the embodiment, the target code file is acquired from the middle table component center, equivalently, the middle table component center is utilized to put and maintain the research center, and the release cost and the maintenance cost of the research component can be reduced.

The present invention addresses to an automated gas injection system in vials with rubber septa, for simultaneous injection of gas in 24 or more positions, with injection pressure control and / or overpressure detection, applied to mass spectrometry analyses and / or gas chromatography. The present invention can be used, for example, in isotopic analyses of geological materials in equipment with carbonate extraction units, in the cleaning and decontamination of tubes to be used in isotopic or chromatographic analyses, and in the removal of contaminants from steam drag or by continuous flow, or coming from the free space of vials or tubes in the analyses of organic and inorganic materials.The application of this invention allows reducing the current times of routine purge (flush) of at very least 3 minutes for every 2 positions (72 positions in total and final time of 108 minutes, in a batch of samples) to a total of 96 positions in 3 minutes, with a reduction of 12 times or more in the flush time, which implies greater analytical capacity to the laboratory, lower external costs of sending samples, less time to obtain results, with technology that is easy to implement in universities and research centers in general, in addition to increasing the lifespan of rubber septa.

This invention relates to the field of molecular marker screening technology, specifically to a SNP combination and method for paternity testing in cynomolgus monkeys. The method provided by this invention utilizes 100 selected specific SNP combinations (SNP1~SNP100) combined with low-depth sequencing for paternity testing in cynomolgus monkeys. The cost per sample is only 1 / 5 to 1 / 10 of existing high-depth sequencing and 1 / 2 of SNP chips. For large-scale experimental monkey populations (such as populations of thousands), this can save hundreds of thousands of yuan in testing costs annually, significantly reducing the economic burden of breeding and management of experimental monkeys, demonstrating extremely high economic efficiency. The method provided by this invention is applicable to cynomolgus monkey population pedigree management, kinship tracing, breeding pair optimization, and genetic quality control, and can be widely applied in experimental monkey breeding farms, primate research centers, and biomedical research institutions.

Provided is a wide-range vibration-free high-speed linear reciprocating scanning device capable of solving mechanical vibration problems during transfer of a scanning head. This work was supported by the IITP (Institute of Information & Communications Technology Planning & Evaluation)-ITRC (Information Technology Research Center) grant (RS-2023-00259676) and Commercialization Promotion Agency for R&D Outcomes'grant (RS-2024-00423610) funded by the Korea government (Ministry of Science and ICT).

This invention discloses an automatic medical coding normalization method, system, and storage medium for multimodal medical data, belonging to the field of medical information technology. The method includes: collecting original textual terms and subject structured information of adverse events and / or concomitant medications, and performing text denoising, format standardization, and data deduplication; generating an initial candidate coding set based on a pre-trained medical language model; performing context-aware semantic disambiguation and rearranging of candidate codes in conjunction with subject structured information; retrieving historically confirmed coding cases from other research centers during the coding confirmation stage, outputting consistency prompts based on the differences between the current context and historical contexts, and receiving reconfirmation, coding modification, or review submission operations; and storing the final confirmation results and retrieving them to an electronic data acquisition system. This invention can improve the accuracy, processing efficiency, traceability, and multi-center coding consistency of medical coding.

The invention discloses a research center project quality risk assessment method based on a clinical test, and the method comprises the steps: obtaining the information of each research center project and a corresponding risk factor, carrying out the grading severity judgment of each project information and the risk factor, giving a score, judging the probability of affecting the quality of the research center project according to the risk factor, and carrying out the evaluation of the quality of the research center project. Each risk factor is endowed with a weight, the score of the grade severity of each risk factor is multiplied by the corresponding weight, the score of each risk factor is obtained and added, the quality risk score of each research center project is obtained, the quality risk of the research center project is evaluated according to the quality risk score of each research center project, and corresponding measures are taken. According to the method, the project quality risk score of each research center is obtained through calculation, the risk identification of the project quality of each research center is realized, corresponding measures are taken according to the evaluation result, existing problems are found and corrected in time, the quality and efficiency of clinical tests are improved, and the overall project quality is ensured.

Provided are Bifidobacterium breve and a probiotic composition comprising the strain. Bifidobacterium breve was deposited in the Bioresource Collection and Research Center of Food Industry Research and Development Institute Taiwan, China on Aug. 8, 2022, and the deposit number BCRC 911145 was obtained. Further provided is use of the strain or a culture thereof in the preparation of a composition for inhibiting maturation of adipocytes, a composition for reducing fat accumulation and / or promoting fat metabolism, a composition for reducing weight, a composition for regulating blood esters, or a composition for regulating blood glucose.

The invention discloses a research center information evaluation method and system based on multi-source data analysis. The method comprises the following steps: acquiring basic information, dynamic data and unstructured text data of a research center to obtain multi-source data; integrating and comparing the multi-source data by using rule matching, NLP analysis and trend comparison methods so as to identify a conformity standard and an expression trend and obtain a comparison result; automatically adjusting and optimizing the index weight through machine learning on the basis of the initial weight set by an expert in combination with the comparison result, and meanwhile, calculating the grouping success rate and the starting speed by applying a prediction model to obtain a calculation result; further based on the key parameters of the project and a basic database, intelligently drawing a test scheme by using a generative model, generating a grouping plan and cost prediction, matching the generated scheme requirement with a calculation result, and intelligently recommending the most adaptive research center; generating a comprehensive report including root cause speculation, semantic extraction and multi-dimensional analysis according to a calculation result; actual project performance feedback is recorded, model calibration is carried out, and data recollection is guided according to data sensitivity and timeliness. By implementing the method provided by the invention, a more efficient, comprehensive and dynamic solution is realized to improve the success rate and management efficiency of clinical tests.

This invention discloses a method and system for intelligent monitoring of the entire clinical trial cycle based on multidimensional data fusion. To address the problems of high false alarm rates, lack of interpretability, and difficulty in forming a monitoring closed loop under multidimensional evidence fusion conditions, this invention acquires and standardizes multidimensional clinical trial data and its source data, constructs an evidence layer graph and a source layer graph, and establishes cross-layer associations to form a two-layer evidence graph. Based on source features, the source credibility is calculated and assigned to evidence layer nodes and edges. Source credibility gating is introduced into the heterogeneous graph Transformer attention mechanism for risk inference and risk score output. The risk score is calibrated for confidence and grouped by trial stage and research center. Group-based shape-preserving prediction is used, and the group warning threshold is determined based on the target false alarm rate to output warning labels and risk levels. The minimum sufficient evidence chain is extracted from the triggering warning object for interpretation. Under the condition of frozen model weights, feedback is used to update the credibility parameters, calibration parameters, and thresholds to form a closed loop, achieving the technical effects of low false alarms, interpretable risk warning grading, and a closed-loop intelligent monitoring throughout the entire cycle.

The invention provides Bifidobacterium breve and a probiotic composition containing the Bifidobacterium breve, the Bifidobacterium breve and the probiotic composition containing the Bifidobacterium breve are deposited in the biological resource preservation and research center of Institute of Food Industry Development of Taiwan in China on August 8, 2022, and the deposit number BCRC 911145 is obtained. The invention also provides application of the strain or the culture thereof in preparation of a composition for inhibiting fat cell maturation, a composition for reducing fat accumulation and / or promoting fat metabolism, a composition for reducing body weight, a composition for regulating blood fat or a composition for regulating blood sugar.

A composition for treating and / or relieving sarcopenia includes Clostridium butyricum M1. A microbial number of Clostridium butyricum M1 ranges from 106 CFU / g to 1012 CFU / g. The composition further includes Bacillus coagulans CC212. Bacillus coagulans CC212 is deposited in Bioresource Collection and Research Center. A deposit number of Bacillus coagulans CC212 is BCRC911233. A microbial number of Bacillus coagulans CC212 is ranges from 106 CFU / g to 1012 CFU / g. A use of the composition is to orally administer the composition to a subject. Clostridium butyricum M1 release a Clostridium butyricum exosome. The Clostridium butyricum exosome could promote muscle growth of the subject. Bacillus coagulans CC212 release a Bacillus coagulans exosome. The Bacillus coagulans exosome and the Clostridium butyricum exosome could effectively reduce a fat mass of the subject. Therefore, the subject could experience an increase in muscle mass and a reduction in fat after taking the composition.

The invention discloses an external-use compound formula for assisting skeletal development and cartilage health of teenagers, and belongs to the technical field of external-use health-care preparations. According to the formula, yak bone marrow peptide, glucosamine hydrochloride, chondroitin sulfate and bone collagen peptide serve as core active ingredients, rose hip oil is matched to serve as a transdermal penetration enhancing component, transdermal absorption of the active ingredients is achieved through reasonable matching, osteoblast metabolism of teenagers (6-18 years old) can be promoted in a targeted mode, the bone mineral density can be increased, and the effect of preventing and treating osteoporosis is achieved. Meanwhile, cartilage matrix synthesis is strengthened, cartilage injury is reduced, and the problem that external health care products are deficient in the teenager skeletal cartilage development stage is solved. According to the technical verification of the Zhejiang traditional Chinese medicine university medicine college modern medicine research center, the formula is high in safety and excellent in transdermal efficiency, adapts to teenager skin barrier characteristics, and has remarkable application value in the fields of teenager skeletal development and cartilage health maintenance.

The invention particularly relates to a regional teaching and research activity management system based on a network platform. According to the regional teaching and research activity management system based on the network platform, a teaching and research center module helps a user to track the progress of a teaching and research activity, retrieve the activity and view details; the teaching and research result module is used for storing and managing various types of resource information precipitated after teaching and research activities are completed, so that resource sharing and user retrieval and viewing are realized; the teaching and research management module realizes whole-process management of teaching and research activities; the teaching and research statistical module carries out comprehensive statistical analysis on development and organization conditions of teaching and research activities of the whole teaching and research platform, and further provides data support for optimization and decision making of the teaching and research activities. According to the regional teaching and research activity management system based on the network platform, teaching and research activity organization efficiency is improved, manual communication cost and time cost are reduced, sharing and utilization of teaching and research resources are promoted, quality and applicability of the teaching and research resources are improved, value of the teaching and research resources is brought into full play, and collaborative development of regional education is facilitated.

The utility model relates to the technical field of water supply and drainage pipelines, in particular to a chip research center water supply and drainage pipeline anti-seismic supporting structure which comprises CB type channel steel, a U-shaped pipe hanging bracket fixedly connected to the top of the CB type channel steel, a supporting screw fixedly connected to the top of the U-shaped pipe hanging bracket, a first C type channel steel fixedly connected to the top of the supporting screw, and a second C type channel steel fixedly connected to the top of the first C type channel steel. A stiffening device is fixedly connected in the first C-shaped channel steel, a pipe clamp is fixedly connected to the outer portion of the U-shaped pipe hanging bracket, a first adjustable hinge A is rotationally connected to the side face of the pipe clamp, a channel steel connecting piece is fixedly connected to the side face of the first adjustable hinge A, and second C-shaped channel steel is fixedly connected to the top of the channel steel connecting piece. The first C-shaped channel steel and the second adjustable hinge A can be fixed together with the cross beam through the U-shaped beam clamp, the supporting effect on the drainage pipeline can be improved through the second C-shaped channel steel and the first C-shaped channel steel, the phenomenon that the pipeline is damaged during an earthquake is avoided, and casualties and property losses are avoided.

This invention is an evaluation kit for lipid peroxidation of human spermatozoa, used to assess male sperm quality in research centers and infertility treatment. The process involves mixing human spermatozoa with PBS at an optimal dose and temperature, then separating them with centrifugal force at a specific speed and time. The separated sperm is diluted with PBS and treated with ferrous sulfate and ascorbic acid at optimal concentrations to promote oxidation. After incubation, trichloroacetic acid is added, and the sample is separated again with a centrifuge to remove peroxides from the spermatozoa. The sample is treated with TBA and NaOH and subjected to thermal stress. Finally, the absorbance is measured with a spectrophotometer at the appropriate wavelength. Through numerical calculations based on MDA, the amount of lipid peroxidation and oxidative damage in the sperm sample is evaluated.

An example method for implementing location based dashboards for clinical trials includes obtaining a target health condition, accessing patient medical claims data and patient prescription claims data stored in one or more databases. For each candidate patient in the set of candidate patients, the method includes removing the candidate patient from the set in response to the candidate patient having demographic data which matches demographic exclusion criteria, the candidate patient having medical history data which matches medical exclusion criteria, or a distance between the candidate patient and a clinical trial study site is greater than a specified distance threshold. The method includes storing a set of eligible candidate patients after selective removal of candidate patients, transmitting a communication to at least one computing device, and displaying the set of eligible candidate patients and the at least one study site on a dashboard map of a user interface.

The invention relates to a process for dehydrating peaches using microwaves, which can be used in food industry enterprises, laboratories and research centers related to dehydration processes.The process, according to the invention, consists in initially selecting peaches suitable for drying, ripe, undamaged, with a humidity of 87-91%, washing and removing the pits therefrom, then slicing them using a slicer into 3 mm thick round slices and arranging a predetermined amount of slices horizontally in a single layer on a flat perforated support in a drying chamber. After that, the slices are dehydrated using microwaves from a magnetron with a total power of 600 W at a regime of 185-245 W, or 800 W at a regime of 210-260 W, or 900 W at a regime of 225-285 W, for 180-225 min until a product humidity of no more than 20% is reached. At the same time, room air with a temperature of 26-30 °C, its relative humidity of 50-65%, normal atmospheric pressure and air flow speed of 1.0-1.8 m / s is used as a thermal agent, intended for removing humidity from the drying chamber.

The invention discloses a research center field check risk assessment method. The method comprises the steps of obtaining project information of each research center and performing risk factor identification; performing grading severity judgment according to the identified risk factors and giving scores; according to the probability that the identified risk factors can influence the on-site checking possibility, each risk is endowed with a weight; multiplying the grading severity score of each risk factor by the corresponding weight, calculating to obtain the score of each risk factor, and adding the scores of all the risk factors to obtain the check risk score of the current research center; according to the risk checking score of the research center, the risk on-site checking possibility of the research center is evaluated, and corresponding measures are taken. Risk factor identification is carried out on acquired project information, risk score calculation is carried out on severity level judgment, the research center is identified in time according to a result to check risk possibility on site, manpower and resources are inclined to carry out preparatory work, and thus on-site check is successfully passed.

The invention discloses a clostridium perfringens bacteriophage cp2p, a bacteriophage preparation and application of the clostridium perfringens bacteriophage cp2p, the classification name of the clostridium perfringens bacteriophage cp2p is Clostridium perfringens bacteriophage cp2p, the preservation unit is China Center for Culture Collection, the preservation number is CCTCC NO.M 20242714, and the preservation time is December 4, 2024. Experiments prove that the clostridium perfringens bacteriophage cp2p has the advantages of high titer, good thermal stability, high splitting rate and the like, and can specifically partially or completely inactivate clostridium perfringens; the clostridium perfringens bacteriophage cp2p can stably survive under an acidic environment condition, so that clostridium perfringens colonized in intestinal tracts can be killed; the clostridium perfringens bacteriophage cp2p can be well proliferated in clostridium perfringens host bacteria, so that the clostridium perfringens bacteriophage cp2p can be subjected to large-scale fermentation culture; the clostridium perfringens bacteriophage cp2p can also be used for preparing feed additives and drinking water additives, the morbidity of clostridium perfringens is greatly reduced, and a new prevention and treatment scheme is provided for replacing antibiotics.

The invention relates to the field of biotechnology. The invention consists in a Lactobacillus reuteri strain SALR01 deposited in the All-Russian Collection of Microorganisms at the G.K. Skryabin Institute of Microbial Biochemistry and Physiology, an independent division of the Federal Research Centre "Pushchino Scientific Center for Biological Research of the Russian Academy of Sciences", under registration number VKM B-3734D. The claimed strain exhibits antagonistic activity against Helicobacter pylori. At the same time, the strain is not toxic to mammalian cells. This makes it possible to use the claimed strain to create probiotics and metabiotics.