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Mesenchymal stem cell storage box

A technology of mesenchymal stem cells and storage boxes, applied in the field of mesenchymal stem cell storage boxes, can solve the problems of uneven cold storage of mesenchymal stem cells, unfavorable mesenchymal stem cell storage, and complicated mesenchymal stem cell process, so as to improve the cold source Utilization rate, time saved, effect not easily lost

Pending Publication Date: 2021-12-21
刘荣怀
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0002] Mesenchymal stem cells are a kind of pluripotent stem cells, which have all the common characteristics of stem cells, that is, self-renewal and multi-directional differentiation capabilities; they are also most widely used in clinical practice, and combined with hematopoietic stem cells can improve the success rate of transplantation and accelerate hematopoietic reconstruction. A kind of multifunctional cell in the tissue, which can differentiate into many kinds of tissue cells; mesenchymal stem cells can repair damaged or diseased tissues and organs, have a strong immune regulation effect, promote the recovery of hematopoietic function, and store mesenchymal stem cells; When mesenchymal stem cells are cryopreserved, it is necessary to place the mesenchymal stem cell storage bag in a freezing tank for cryopreservation. The temperature control unit in the prior art is located outside the mesenchymal stem cell storage box. The cold source of this storage method utilizes Low efficiency will lead to energy waste; at the same time, it is necessary to open the freezer to search for it when taking it, which is time-consuming and laborious, resulting in time loss for the staff
[0003] For example, a Chinese patent with the application number CN201820273449.9 discloses a dental pulp mesenchymal stem cell storage device, which includes an outer tank, an inner tank and a nitrogen storage layer, and a partition is arranged between the outer tank and the nitrogen storage layer. Heat layer, the heat insulation layer is aluminum foil coated with paraffin, the nitrogen storage layer is located between the heat insulation layer and the inner tank body, and the outer tank body, heat insulation layer, inner tank body and the top of the nitrogen storage layer are welded with a sealing ring, A circular sealing cover is hinged on the right side of the upper end of the sealing ring body, and a handle is provided at the side end of the sealing cover. An oxygen inlet pipe is arranged in the settling hole on the sealing cover through thread fit, and the oxygen inlet pipe passes through the settling hole to fix the sealing cover on the On the sealing ring body, the lower end of the oxygen inlet pipe and the sealing ring body are connected through thread fit, and the inner tank body is symmetrically provided with slide grooves left and right. Accurate numbering has the advantages of simple device structure and good freezing effect; however, the temperature control unit of this technical solution is located outside the mesenchymal stem cells, the utilization rate of the cold source is low, and the process of taking mesenchymal stem cells is relatively complicated, and it is difficult for The cold storage of mesenchymal stem cells is uneven, which is not conducive to the storage of mesenchymal stem cells, resulting in the limitations of this technical solution

Method used

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Effect test

Embodiment approach

[0038] As an embodiment of the present invention, the temperature control unit includes an annular pipeline 17, a No. 1 air inlet pipe 13, a No. 2 air inlet pipe 14, a No. 1 air outlet pipe 15 and a No. 2 air outlet pipe 16; The surface is fixedly connected with No. 1 air intake pipe 13, No. 2 air intake pipe 14, No. 2 air outlet pipe 16 and No. 1 air outlet pipe 15; The air pipes 15 all pass through the box body 1 and communicate with the cylindrical cavity 18; the annular duct 17 is fixedly connected between the No. 1 air inlet pipe 13 and the No. 1 air outlet pipe 15; the annular duct 17 is located inside the cylindrical cavity 18;

[0039] When working, the staff uses the controller to control the second air outlet pipe 16 to discharge the air in the cylindrical cavity 18, and then slowly injects the second air inlet pipe 14 into liquid nitrogen, and at the same time the staff uses the controller to control the first air inlet pipe 13 Oxygen is introduced into the annular ...

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Abstract

The invention relates to the technical field of mesenchymal stem cell storage, in particular to a mesenchymal stem cell storage box which comprises a box body and a temperature control unit and further comprises a driving unit, threaded rods, a storage box body and a controller. The box body is cylindrical, and a cylindrical cavity is formed in the box body; an annular groove is formed in the upper surface of the box body; the other ends of the two threaded rods penetrate through the box body, extend to the exterior of the box body and are fixedly connected with a first gear, the two threaded rods are rotationally and hermetically connected with the box body, and the driving unit is arranged between the two threaded rods; the lower part of the box body is fixedly connected with a protective shell; and the temperature control unit controls the storage temperature of the mesenchymal stem cells, the driving unit controls the threaded rod so as to control the lifting of the storage box, a worker can take and use the mesenchymal stem cell storage bag more conveniently, meanwhile, the temperature control unit is arranged in the storage box, the cooling capacity is not prone to loss, and the utilization rate of the cooling capacity is improved, so that the practicability is improved.

Description

technical field [0001] The invention relates to the technical field of mesenchymal stem cell storage, in particular to a mesenchymal stem cell storage box. Background technique [0002] Mesenchymal stem cells are a kind of pluripotent stem cells, which have all the common characteristics of stem cells, that is, self-renewal and multi-directional differentiation capabilities; they are also most widely used in clinical practice, and combined with hematopoietic stem cells can improve the success rate of transplantation and accelerate hematopoietic reconstruction. A kind of multifunctional cell in the tissue, which can differentiate into many kinds of tissue cells; mesenchymal stem cells can repair damaged or diseased tissues and organs, have a strong immune regulation effect, promote the recovery of hematopoietic function, and store mesenchymal stem cells; When mesenchymal stem cells are cryopreserved, it is necessary to place the mesenchymal stem cell storage bag in a freezing...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A01N1/02B65G1/04F25D3/10F25D17/04F25D29/00
CPCA01N1/0257B65G1/045F25D3/105F25D17/04F25D29/003
Inventor 刘荣怀杨西岐吕雪雅
Owner 刘荣怀
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