Composition for resisting tooth sensitivity, preparation method and application thereof, and oral care product containing composition

A technology for tooth sensitivity and oral care, applied in the field of oral care, can solve problems such as failure of bioactive glass, and achieve the effects of improving bioavailability, resisting erosion, and isolating water molecules

Pending Publication Date: 2022-01-11
四川涑爽医疗用品有限公司 +2
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0008] In order to solve the problem that bioactive glass is prone to failure in aqueous oral care products, the present invention pro

Method used

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  • Composition for resisting tooth sensitivity, preparation method and application thereof, and oral care product containing composition
  • Composition for resisting tooth sensitivity, preparation method and application thereof, and oral care product containing composition
  • Composition for resisting tooth sensitivity, preparation method and application thereof, and oral care product containing composition

Examples

Experimental program
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Embodiment 1

[0035] The present embodiment provides an anti-tooth sensitivity composition, comprising the following components by weight: 0.1 part of calcium sodium phosphosilicate, 0.5 part of PVM / MA copolymer, 5 parts of potassium nitrate, 0.1 part of sodium fluoride and PEG400 95 parts; The particle diameter of calcium sodium phosphosilicate in the present embodiment is 10~50nm.

[0036] The preparation method of calcium sodium phosphosilicate in the present embodiment is: take by weight SiO 2 42 parts, CaO 20 parts, K 2 O 15 parts and P 2 o 5 5 parts, mix the components and put them at 1450°C for 70 minutes to get a uniform mixture, place the resulting mixture in a normal temperature water bath to quench it, dry it, crush it, and grind it to a particle size of 10-50nm Particles, that is, to obtain the calcium sodium phosphosilicate.

Embodiment 2

[0038] The present embodiment provides an anti-tooth sensitivity composition, comprising the following components by weight: 1 part of calcium sodium phosphosilicate, 3 parts of PVM / MA copolymer, 7 parts of potassium nitrate, 4 parts of sodium fluoride and PEG -60 85 parts of hydrogenated castor oil; the particle diameter of calcium sodium phosphosilicate in the present embodiment is 10~50nm.

[0039] The preparation method of calcium sodium phosphosilicate in the present embodiment is: take by weight SiO 2 42 parts, CaO 20 parts, K 2 O 15 parts and P 2 o 5 5 parts, mix the components and put them at 1450°C for 70 minutes to get a uniform mixture, place the resulting mixture in a normal temperature water bath to quench it, dry it, crush it, and grind it to a particle size of 10-50nm Particles, that is, to obtain the calcium sodium phosphosilicate.

Embodiment 3

[0041] The present embodiment provides an anti-tooth sensitivity composition, comprising the following components by weight: 3 parts of calcium sodium phosphosilicate, 5 parts of PVM / MA copolymer, 8.5 parts of potassium nitrate, 6 parts of sodium fluoride and propylene glycol 77.5 parts; The particle diameter of calcium sodium phosphosilicate in the present embodiment is 10~50nm.

[0042] The preparation method of calcium sodium phosphosilicate in the present embodiment is: take by weight SiO 2 42 parts, CaO 20 parts, K 2 O 15 parts and P 2 o 5 5 parts, mix the components and put them at 1450°C for 70 minutes to get a uniform mixture, place the resulting mixture in a normal temperature water bath to quench it, dry it, crush it, and grind it to a particle size of 10-50nm Particles, that is, to obtain the calcium sodium phosphosilicate.

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Abstract

The invention relates to a composition for resisting tooth sensitivity, a preparation method and application of the composition and an oral care product containing the composition, and belongs to the technical field of oral care. In order to solve the problem that bioactive glass is easy to lose efficacy in a water-containing system, the invention provides a composition for resisting tooth sensitivity, which comprises the following components: sodium calcium phosphate silicate, a PVM/MA copolymer, potassium nitrate, sodium fluoride and a first solvent. The composition can quickly form a film on the tooth surface, effectively resist dentin hypersensitivity, form an environment rich in calcium and phosphorus ions, and promote remineralization of the tooth surface. According to the invention, the nano-scale sodium calcium phosphate silicate is coated in the PVM/MA copolymer to form a stable composition which is not easily damaged by external force and plays a role in isolating water molecules, so that the composition can stably exist in a water-containing system, and the problem of application limitation of the sodium calcium phosphate silicate is solved. The composition disclosed by the invention can be used as a special-effect additive and is applied to oral care products of various dosage forms.

Description

technical field [0001] The invention belongs to the technical field of oral care, and in particular relates to an anti-tooth sensitivity composition, a preparation method and application thereof, and an oral care product containing the composition. Background technique [0002] Dentin hypersensitivity, as a common and frequently-occurring disease in the oral cavity, is an oral disease with a relatively high incidence in adults, and it is also one of the common causes of toothache clinically. According to relevant statistics, nearly 44% of people in my country suffer from dentin hypersensitivity in varying degrees. It is bothering people's daily life, and severe cases can cause other concurrent diseases such as oral cavity and heart. When the tooth is subjected to external stimuli, such as temperature (cold, heat), chemical substances (sour, sweet) and mechanical action (rubbing or biting hard objects), it will immediately cause sore symptoms, which are characterized by rapi...

Claims

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Application Information

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IPC IPC(8): A61K8/25A61K8/21A61K8/19A61K8/81A61Q11/00
CPCA61K8/25A61K8/21A61K8/19A61K8/8164A61Q11/00
Inventor 关晴光肖丽娟李明邹萍范玉奇
Owner 四川涑爽医疗用品有限公司
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