25 results about "Calcium/Sodium" patented technology

The invention relates to the technical field of oral biomedical materials, and particularly discloses a nanoscale calcium sodium phosphosilicate material composition and a preparation method thereof. The nanoscale calcium sodium phosphosilicate material composition is prepared from bioactive glass, glass silica gel, calcium salt and phosphate, and the oxide composition of the bioactive glass is limited. The nano-scale sodium calcium phosphate silicate material composition has high biological activity and can fully play a mineralization role in a saliva environment, and hydroxyapatite newly formed in the mineralization process can fully fill defects and holes in the tooth surface, so that the microhardness of the tooth surface is effectively improved within a short time, and the tooth quality is improved. The repair of damaged teeth is effectively realized.

This invention relates to the fields of high-purity sodium preparation and safe disposal of sodium-calcium slag, and discloses a method and apparatus for preparing high-purity sodium and safely disposing of sodium-calcium slag using a gravity separation-controlled combustion-alkali leaching process. The method includes the following steps: (1) gravity separation of liquid sodium slag to obtain pure sodium and high-calcium sodium slag; (2) calcination of the high-calcium sodium slag to obtain calcined slag; (3) leaching of the calcined slag with an alkaline solution to obtain sodium hydroxide solution and calcium hydroxide. The method and apparatus provided by this invention have advantages such as high efficiency in separating sodium and calcium, saving separation time, safe and controllable production process, and continuous production process. It provides a safe and efficient method for the preparation of high-purity sodium and safely disposes of the new sodium-calcium slag generated by this method, realizing the continuous preparation of high-purity sodium and the safe recycling of new sodium-calcium slag.

The present invention relates to the field of recycling of sodium slag in the electrolysis process of metallic sodium, and discloses a method for recycling metallic sodium by using density gradient liquid. The method includes: mixing liquid sodium slag with density gradient liquid, and then performing high-gravity stratification to obtain metallic sodium, high-calcium sodium slag and density gradient liquid, wherein the density of the density gradient liquid is 0.97 - 1.55 g / mL. The method provided by the present invention has the advantages of high separation efficiency of sodium and calcium. The separated metallic sodium can be used as a product, and the separated density gradient liquid has the advantages of being recyclable repeatedly, etc., so that the low-value hazardous solid waste sodium slag generated in the process of preparing metallic sodium by electrolyzing sodium chloride is secondarily developed, and the metallic sodium mixed therein is effectively recovered, realizing the reduction of sodium slag and the high-value utilization of resources.

The present invention relates to a cosmetic composition comprising, in a physiologically acceptable medium, composite particles comprising a substrate formed from mica and from bismuth oxychloride coated with at least one mineral pigment and at least one nacre, chosen from composite particles comprising at least one support chosen from mica, synthetic fluorphlogopite or calcium sodium borosilicate, and completely or partially coated with one or more layers of metal oxides, in particular chosen from titanium dioxide, iron oxide, tin oxide and mixtures thereof.It also relates to the process for giving skin, and in particular facial skin, a uniform complexion and a rosy tonality, while at the same time retaining the natural appearance of the skin, which consists in applying at least one coat of a composition as defined above to the surface of the targeted skin.

The invention discloses a method for preparing an alkali metal material from halogenated alkali metal salt and high-calcium sodium, and relates to the technical field of alkali metal recovery and preparation. The halogenated alkali metal salt is dried and dewatered through drying and dewatering equipment; crushing or dissociating the high-calcium sodium through sodium slag crushing equipment; introducing the halogenated alkali metal salt in the step S100 and the high-calcium sodium in the step S200 into a high-temperature vacuum furnace, and carrying out a replacement reaction under the protection of inert gas; the alkali metal material serving as a replacement reaction product is guided into a storage tank in a distillation mode to be stored; compared with the prior art, the method has the technical advantages that the high-calcium sodium obtained by electrolyzing sodium chloride is relatively thoroughly treated and subjected to impurity removal through the replacement reaction of the halogenated alkali metal salt and the high-calcium sodium, the sodium is purified for subsequent application, the calcium accounting for the second position by mass is also treated, the post-treatment process is reduced, and the economical efficiency is further improved; equipment and energy required by the method are appropriate in cost, high in pertinence and safe to operate.

The present invention relates to a method for treating an aqueous effluent, said effluent comprising: - a metal chosen from the list consisting of copper, zinc, nickel, chromium, tin, aluminum, iron, cobalt, silver, gold, palladium and rhodium, alone or in combination, - a salt comprising an anion chosen from the list consisting of sulfate, chloride, nitrate, fluoride, sulfamate, acetate, carbonate, citrate, cyanide, hydroxide, nitrite, oxide and phosphate alone or in combination, and a cation chosen from the list consisting of calcium, sodium, potassium, ammonium, quaternary ammonium, iron, magnesium, pyridinium and lithium alone or in combination, the method comprising a step a) of bringing said effluent into contact with at least one alumina-based solid, said solid being obtained by a method comprising the following steps: i) abruptly dehydrating by flashing an aluminum hydroxide or an oxyhydroxide aluminum,to obtain an active alumina powder; ii) the active alumina powder obtained in step i) is shaped so as to obtain a solid in the form of a ball or extrudate; iii) the solid obtained in step ii) is heat treated; iv) the heat-treated solid obtained in step iii) is hydrothermally treated; v) the treated solid obtained in step iv) is calcined.,

The invention belongs to the technical field of pharmaceutical chemistry polymorphic forms, and particularly relates to an ARNi compound calcium-sodium compound, crystal forms A and B thereof, and a preparation method and application of the ARNi compound calcium-sodium compound.

The present invention relates to a method for treating an aqueous effluent, the effluent comprising: - a metal selected from the list consisting of copper, zinc, nickel, chromium, tin, aluminium, iron, cobalt, silver, gold, palladium and rhodium, alone or in combination; - a salt comprising an anion chosen from the list consisting of sulphate, chloride, nitrate, fluoride, sulphamate, acetate, carbonate, citrate, cyanide, hydroxide, nitrite, oxide and phosphate alone or in combination, and a cation chosen from the list consisting of calcium, sodium, potassium, ammonium, quaternary ammonium, iron, magnesium, pyridinium and lithium alone or in combination, the method comprising a step a) of bringing the effluent into contact with at least one alumina-based solid, the solid being obtained by a method comprising the following steps: i) an aluminium hydroxide or an aluminium oxide hydroxide undergoes sudden dehydration, by flashing, in order to obtain an active alumina powder; ii) the active alumina powder obtained in step i) is shaped to obtain a solid in the form of a bead or extrudate; iii) the solid obtained in step ii) is heat treated; iv) the heat-treated solid obtained in step iii) undergoes hydrothermal treatment; v) the treated solid obtained in step iv) is calcined.

The invention discloses a preparation process and application of potassium calcium sodium phosphosilicate fluoride, and belongs to the technical field of biological materials. By optimizing the low-temperature fluoride raw material and the bioactive glass powder and under the sintering treatment process, high fluorine loading capacity can be obtained, the fluorine element is combined with the bioglass in a chemical bond form, the stability is higher, and the application effect of the bioglass is guaranteed; and low-temperature sintering treatment is low in energy consumption, large-scale production can be achieved, and operability is high. Besides, the fluorinated sodium potassium calcium phosphosilicate prepared by the invention is high in biological safety, can play remarkable roles in inhibiting bacteria, preventing dental caries and tooth sensitivity symptoms, promoting oral soft tissue healing, inhibiting gingivitis and freshening breath when being applied to preparation of medical oral products and daily chemical products, can also be applied to preparation of foods, and has a wide application prospect. Especially in the preparation of betel nuts, as an active material, the betel nuts can relieve tooth sensitivity symptoms, promote oral soft tissue healing and inhibit gingivitis.

The present invention discloses a highly stable whitening and anti-aging atomizing solution. The preparation raw materials include enzyme activity inhibitors, polysaccharide substances, calcium sodium phosphosilicate, skin conditioners, polypeptides, vitamins, edible flavors, and polar solvents. The obtained atomizing solution can improve the cell discrimination ability and regulate the half-life of blood proteins, thereby effectively enhancing the human immune function; activate the fibroblasts generated by the human dermis, significantly promote the synthesis of collagen in the human body, effectively improve the stratum corneum, promote the skin to be soft and elastic, and make the skin young and plump; can establish a network structure on the skin surface to achieve long-term water locking, effectively relieve skin dryness and desquamation, and form a natural defense barrier for the skin; has super antioxidant ability, and enhances the skin's anti-photoaging and anti-ultraviolet radiation performance. Moreover, it has good thermal stability, and the active ingredients will not decompose under the high temperature condition of 220°C. At the same time, it can promote the rapid atomization of the atomizing solution, and the formed mist has a high saturation.

The invention provides a method for treating systemic sclerosis (SSc) by using sodium calcium edetate (EDTA), and relates to the field of systemic sclerosis treatment, and the method comprises the following steps: S100, using EDTA as a core therapeutic agent, and reducing the fibrosis degree of the skin and internal organs of a patient in an intravenous infusion mode; s200, colchicine and nifedipine tablets are orally taken in a combined mode, and anti-fibrosis synergistic treatment is formed. According to the application, systemic sclerosis (SSc) is treated by intravenous infusion of sodium calcium edetate (EDTA), so that fibrosis of organs such as skin and lung of a patient is effectively improved, occurrence of complications such as infection is reduced, reversibility improvement of skin and pulmonary fibrosis (for example, skin elasticity modulus is reduced by more than or equal to 30%) is realized, and the curative effect of the skin and pulmonary fibrosis is improved. The EDTA is used for replacing or partially replacing high-toxicity immunosuppressants such as cyclophosphamide, complications such as myelosuppression and serious infection are avoided, the infection incidence rate of a patient is reduced by 40% or above, and the treatment safety is remarkably improved.

The present disclosure provides bio-material composition, comprising a dry potassium phosphate based mixture comprising: MgO, monobasic potassium phosphate, monobasic sodium phosphate, proteoglycans, calcium sodium phosphosilicate, and a plurality of spherically-shaped polymers, wherein a weight percent ratio of monobasic potassium phosphate to MgO is between about 3:1 and 1:1, wherein the dry potassium phosphate based mixture is configured to be mixed with the aqueous solution to thereby form a reabsorbable bio-material slurry, wherein the spherically-shaped polymers are between about 1-5 weight percent of the dry composition, and wherein the spherically-shaped polymers are absorbed faster than the remaining components of the reabsorbable bio-material slurry to thereby form pockets within the bio-material composition that enhance reabsorption of the bio-material co

The present disclosure provides bio-material composition, comprising a dry potassium phosphate based mixture comprising: MgO, monobasic potassium phosphate, monobasic sodium phosphate, proteoglycans, calcium sodium phosphosilicate, and a plurality of spherically-shaped polymers, wherein a weight percent ratio of monobasic potassium phosphate to MgO is between about 3:1 and 1:1, wherein the dry potassium phosphate based mixture is configured to be mixed with the aqueous solution to thereby form a reabsorbable bio-material slurry, wherein the spherically-shaped polymers are between about 1-5 weight percent of the dry composition, and wherein the spherically-shaped polymers are absorbed faster than the remaining components of the reabsorbable bio-material slurry to thereby form pockets within the bio-material composition that enhance reabsorption of the bio-material composition.

The invention discloses a high-water-solubility L-ascorbic acid-2-phosphate calcium sodium salt as well as a preparation method and application of the high-water-solubility L-ascorbic acid-2-phosphate calcium sodium salt. The 1% aqueous solution of the calcium sodium salt is free of precipitation after standing at 25 DEG C for 24 hours, and the 600 nm light transmittance of the 0.1% aqueous solution is greater than or equal to 95%. The preparation method comprises the following steps: reacting L-ascorbic acid with sodium trimetaphosphate to generate AMP sodium salt, slowly dropwise adding calcium lactate or calcium gluconate at low temperature, adding 0.1-0.5 wt% of sodium citrate as an anti-precipitation protective agent, and carrying out low-temperature spray drying (inlet air is 150-170 DEG C and outlet air is 65-75 DEG C) and cold nitrogen cooling to obtain the product. The product is specially applied to water sprinkling for aquaculture, can be completely dissolved within 30 seconds under the concentration of 10g / L, is clear and transparent in solution, effectively solves the problems of slow dissolution, turbidity and precipitation of the traditional AMP calcium sodium salt during water sprinkling, and remarkably improves the biological utilization efficiency.

White, translucent, colourable ceramic compound based on a calcium sodium frit that devitrifies sodium anorthite in the SiO2—Al2O3—CaO—Na2O system to be used as the main raw material (60%-90%) in porcelain stoneware compositions for the production of large format sheets (up to 2 metres). The frit will provide parts with an elevated whiteness without the need to introduce opacifiers such as zirconium silicate, although these could also be added, together with aluminas, to obtain a higher level of whiteness. On the other hand, it will provide the ceramic compound a high translucency, which will allow it to have a high colour development with the addition of inorganic pigments.

The present invention relates to a method for treating an aqueous effluent, the effluent comprising: - a metal selected from the list consisting of copper, zinc, nickel, chromium, tin, aluminium, iron, cobalt, silver, gold, palladium and rhodium, alone or in combination; - a salt comprising an anion chosen from the list consisting of sulphate, chloride, nitrate, fluoride, sulphamate, acetate, carbonate, citrate, cyanide, hydroxide, nitrite, oxide and phosphate alone or in combination, and a cation chosen from the list consisting of calcium, sodium, potassium, ammonium, quaternary ammonium, iron, magnesium, pyridinium and lithium alone or in combination, the method comprising a step a) of bringing the effluent into contact with at least one alumina-based solid, the solid being obtained by a method comprising the following steps: i) an aluminium hydroxide or an aluminium oxide hydroxide undergoes sudden dehydration, by flashing, in order to obtain an active alumina powder; ii) the active alumina powder obtained in step i) is shaped to obtain a solid in the form of a bead or extrudate; iii) the solid obtained in step ii) is heat treated; iv) the heat-treated solid obtained in step iii) undergoes hydrothermal treatment; v) the treated solid obtained in step iv) is calcined.

The present invention relates to a method for preventing or treating hyperkalemia in a subject. The method comprises a first-stage dosing regimen in which poly(2-fluoroacrylic acid-pentaerythritol triallyl ether) iron calcium sodium salt is orally administered to the subject 3 times a day, 3 g to 48 g each time, for 2 consecutive days. Optionally, the method comprises a second-stage dosing regimen in which 3 g to 48 g of poly(2-fluoroacrylic acid-pentaerythritol triallyl ether) iron calcium sodium salt is orally administered to the subject once a day or once every other day.

Disclosed in the present invention are a toothpaste for repairing tooth enamel and a preparation method therefor. The toothpaste of the present invention comprises calcium phosphosilicate, calcium sodium phosphosilicate, porous silica, polyethylene glycol, sodium fluoride, olaflur, hydrated silica, and a toothpaste matrix component. According to the present invention, the release speed of calcium and phosphate ions is regulated and controlled by optimizing the ratio of the calcium phosphosilicate to the calcium sodium phosphosilicate, and in addition, the fluoride and the polyethylene glycol are loaded in the porous silica, such that the hydrogen bond effect between the fluoride and the polyethylene glycol can further reduce the release speed of the fluoride in the oral cavity, a small number of fluorine ions released in the early stage of tooth brushing can promote remineralization, and a large number of fluorine ions released in the later stage of tooth brushing can convert newly generated hydroxyapatite into fluorapatite with higher hardness.

Title: Composition comprising an absorbent pigment and at least one particular mother-of-pearl based on aluminum oxide and various iron oxides, for a shiny effect and method for its implementation. The present invention relates to a solid cosmetic composition comprising: * at least one absorbent pigment comprising a substrate in the form of calcium sodium borosilicate platelets and a coating, applied to the substrate, comprising titanium, iron and tin; the coating comprising a) optionally a layer 1 comprising or consisting of at least one tin oxide, tin hydroxide and / or hydrated tin oxide, b) a layer 2 comprising at least one metal oxide, metal hydroxide and / or hydrated metal oxide and c) a layer 3 comprising at least one metal oxide, metal hydroxide and / or hydrated metal oxide;at least one of the layers 2 and 3 comprising at least two different metal ions, selected from titanium, iron, tin, and mixtures thereof; layers 2 and 3 being interrupted by at least one spacer layer;* at least one first nacre consisting of an aluminium oxide substrate in the form of platelets having an aspect ratio of at least 85, and a coating comprising a layered structure consisting of a first layer composed of hematite and / or goethite and a second layer composed of magnetite, and optionally, another colourless dielectric layer on the magnetite layer, in this sequence, on the substrate;* optionally at least one second nacre consisting of aluminium oxide and titanium dioxide, and optionally of tin oxide;* at least one non-volatile hydrocarbon oil, polar or non-polar, or silicone-based, as well as mixtures thereof. It also relates to a makeup and / or lip care process, consisting of applying said composition.

The present disclosure relates to a method for treating a bone defect using a bio-material with increased porosity and reabsorption characteristics, the method comprising: (a) mixing a dry potassium phosphate based mixture with an aqueous solution to form a reabsorbable bio-material slurry, wherein the dry potassium phosphate based mixture comprises MgO, monobasic potassium phosphate, monobasic sodium phosphate, proteoglycans, and calcium sodium phosphosilicate, wherein a weight percent ratio of monobasic potassium phosphate to MgO is between about 3:1 and 1:1, wherein the dry potassium phosphate based mixture is configured to be mixed with the aqueous solution to thereby form a reabsorbable bio-material slurry, wherein the proteoglycans are between about 1-10 weight percent of the dry composition, (b) accessing a void of a bone defect within a bone, and (c) filling the void with the reabsorbable bio-material slurry, wherein the reabsorbable bio-material slurry is osteoconductive and osteoinductive, thereby enabling new bone growth in the void.

The present invention provides a gadobutrol injection and a preparation method thereof, belonging to the technical field of contrast agents. The preparation method of the gadobutrol injection provided by the present invention comprises the following steps: (1) mixing a pH regulator with a part of water to obtain a first solution; (2) mixing the first solution with trometamol, cobutriol calcium, gadobutrol and the remaining water to obtain the gadobutrol injection; the mixing temperature in the steps (1)-(2) is ≤50°C. By changing the pH adjustment sequence, the present invention avoids local over-acidification during the final adjustment; at the same time, trometamol is used as a pH buffer, which has a stronger buffering capacity compared with phosphates; cobutriol calcium is used as a metal ion chelating agent in combination, and has a stronger chelating ability for free gadolinium ions compared with cobutriol calcium sodium, thereby reducing the content of free gadolinium ions in the gadobutrol injection.

The present disclosure relates to a method for treating a bone defect using a bio-material with increased porosity and reabsorption characteristics, the method comprising: (a) mixing a dry potassium phosphate based mixture with an aqueous solution to form a reabsorbable bio-material slurry, wherein the dry potassium phosphate based mixture comprises MgO, monobasic potassium phosphate, monobasic sodium phosphate, proteoglycans, and calcium sodium phosphosilicate, wherein a weight percent ratio of monobasic potassium phosphate to MgO is between about 3:1 and 1:1, wherein the dry potassium phosphate based mixture is configured to be mixed with the aqueous solution to thereby form a reabsorbable bio-material slurry, wherein the proteoglycans are between about 1-10 weight percent of the dry composition, (b) accessing a void of a bone defect within a bone, and (c) filling the void with the reabsorbable bio-material slurry, wherein the reabsorbable bio-material slurry is osteoconductive and osteoinductive, thereby enabling new bone growth in the void.

The invention provides a sodium calcium edetate composition as well as a preparation method and application thereof, and the preparation method comprises the following steps: S1, adding sodium calcium edetate into a glucose-phosphate buffer solution, and uniformly dispersing to obtain a mixed solution I; s2, adding pulegone, tangeretin and phospholipid into an organic solvent, performing ultrasonic treatment, and performing rotary evaporation under reduced pressure to obtain a mixed solution II; s3, mixing the mixed solution II and the mixed solution I, performing rotary evaporation under reduced pressure, and performing freeze drying to obtain a sodium calcium edetate eutectic; and S4, carrying out hydroxyl modification on the sodium calcium edetate eutectic to obtain the sodium calcium edetate composition. The sodium calcium edetate composition can adsorb and rapidly and efficiently promote discharge of various heavy metal ions, significantly reduces the content of heavy metals accumulated in bones, blood and viscera, does not cause loss of essential basic elements such as calcium, zinc and the like in the body, does not cause mineral imbalance in the body, does not cause gastrointestinal mucosa injury, and can be used for treating gastrointestinal diseases. The traditional Chinese medicine composition can be safely used for treating chronic poisoning caused by heavy metals for a long time.

The present invention relates to a dry suspension comprising poly(2-fluoroacrylic acid-pentaerythritol triallyl ether) iron calcium sodium salt, a suspending agent, and silicon dioxide or a solid powder flavor, and a preparation method therefor; the present invention further relates to the use of the dry suspension in the treatment of hyperkalemia.

The invention discloses high-oil-loading temperature-sensitive biphase gel as well as a preparation method and application thereof, and belongs to the technical field of biomedical materials and cosmetics. The gel is prepared by taking a long-chain alkyl grafted and modified polymer matrix as a basis and reacting with an inorganic cross-linking agent calcium sodium borosilicate. The preparation method comprises the following steps: reacting the component A with the component B in a solvent to obtain a hydrophobically modified polymer matrix; and then mixing with calcium sodium borosilicate in water, and forming gel under the synergistic effect of a physical crosslinking point formed by hydrophobic aggregation of an alkyl chain and ionic crosslinking. The oil carrying capacity of the gel is improved, and the oil carrying capacity can reach 20 wt% or above. Besides, by introducing an alkyl chain, a polymer chain can generate chain curling and intermolecular association in water along with temperature rise, the effect is synergistic with ionic crosslinking, the gel is endowed with a temperature-sensitive characteristic, the gel generates reversible sol-gel conversion near the body temperature, and in-situ fitting with the skin or a wound surface is realized. The application potential is realized in the fields of drug sustained-release dressings and functional cosmetics.