14 results about "Dentine Sensitivity" patented technology

The invention discloses nano calcium polyphosphate-containing toothpaste with a repairing effect and a preparation method of the nano calcium polyphosphate-containing toothpaste. The toothpaste is prepared from the following components in percentage by mass: 5 to 15 percent of water, 55 to 75 percent of a polyol humectant, 0.2 to 1 percent of sodium carboxymethyl cellulose, 2 to 8 percent of sodium lauryl sulfate, 15 to 20 percent of silicon dioxide, 0.01 to 0.4 percent of menthol, 0.01 to 0.07 percent of a preservative and 0.01 to 0.1 percent of nano calcium polyphosphate. The nano calcium polyphosphate is introduced into a toothpaste system, and the nano calcium polyphosphate can be effectively attached to and actively repair microscopic defects on the enamel surface by utilizing the high specific surface activity and biomimetic mineralization characteristics of the nano calcium polyphosphate. The toothpaste not only has a conventional cleaning function, but also can remarkably reduce tooth surface roughness, recover microhardness and relieve dentin sensitivity, daily active repair of tooth hard tissue is achieved, and the defect of existing toothpaste in the aspect of direct structural repair is overcome.

The invention relates to a pharmaceutical composition for reducing dentin hypersensitivity and a preparation method thereof, and belongs to the technical field of biological medicine, the pharmaceutical composition comprises chanterelle extract, rabdosia rubescens leaf extract, eggshell membrane protein peptide and bifidobacterium thermophile fermentation extract; the cantharellus cibarius extract is obtained by sequentially performing enzymolysis on cantharellus cibarius through compound enzyme, ginger protease and serratipeptidase and purifying enzymatic hydrolysate through an AB-8 macroporous resin column. The rabdosia rubescens leaf extract is obtained by ultrasonically extracting rabdosia rubescens leaves with an ethanol water solution and purifying an extracting solution with a composite filler adsorption column. The eggshell membrane protein peptide is obtained by carrying out enzymolysis on a shell membrane by virtue of ginger protease and ficin and purifying an enzymatic hydrolysate by virtue of a G-25 sephadex column. The fermentation extract of the bifidobacterium thermophilus is obtained by purifying fermentation liquor of the bifidobacterium thermophilus through an SP agarose gel FF column. All the components are compounded according to a specific ratio and have a synergistic effect, so that the dentin hypersensitivity can be relieved safely in a multi-effect manner.

The invention discloses tooth whitening gel and a preparation method thereof, and relates to the technical field of tooth gel. The toothpaste comprises the following components: 2% of sodium carboxymethyl cellulose, 10% of glycerol, 4% of polyethylene glycol-400, 6% of urea peroxide, 1% of potassium nitrate, 0.5% of menthol, 3% of xylitol, a pH regulator for regulating the pH value to 6.5, and the balance of deionized water. The urea peroxide realizes nanoscale dispersion under a low-temperature wet grinding process, and cooperates with the potassium nitrate to block neural signal conduction through an ion channel, so that the whitening effect and dentin sensitivity problems are synchronously solved; xylitol can reduce irritation and form a'whitening-desensitization 'synergistic system; a three-time equal-component feeding method is combined with temperature control, so that sodium carboxymethyl cellulose is fully swelled and forms a stable net-shaped structure, and the caking defect caused by traditional one-time feeding is avoided.

This invention discloses a highly antibacterial oral sealant for treating dentin hypersensitivity, its preparation method, and its application. The sealant's raw materials include calcium oxalate, diammonium hydrogen phosphate, tetraethyl orthosilicate, and cerium nitrate hexahydrate. It is a bioactive material that can generate hydroxyapatite in a short time and exhibits good biocompatibility. This sealant regulates and stabilizes Ce... 3+ Ce 4+ The ratio of these components results in high antibacterial properties, making it suitable for use as an oral sealant. It primarily works by sealing the gaps between the pits and fissures of teeth to block bacterial invasion, thereby improving the acid resistance of tooth enamel and preventing cavities. At the same time, this material has good bactericidal properties, allowing for deeper bacterial removal and ensuring a clean oral environment.

The invention provides a toothpaste composition with tooth strengthening and strengthening effects as well as a preparation method and application thereof, and relates to the technical field of traditional Chinese medicines. The toothpaste composition comprises active components and auxiliary materials, wherein the active components comprise halite, gypsum, fructus psoraleae, pepper, radix angelicae, mint, eclipta alba, divaricate saposhnikovia root, asarum, radix aconiti lateralis praeparata and compound probiotic freeze-dried powder; the compound probiotic freeze-dried powder consists of kluyveromyces marxianus freeze-dried powder and lactobacillus salivarius freeze-dried powder; the auxiliary material comprises a compound bacteriostatic agent; the compound bacteriostatic agent is prepared from chamomile blue and a tussilago farfara extract. The toothpaste composition prepared by respectively extracting the raw materials through a specific preparation method is not only good in stability, but also capable of remarkably improving various inflammations and bleeding of periodontal diseases, improving the tooth health problem of users with dentin sensitivity and meeting the requirements of various users.

The invention discloses an integrated measuring system for evaluating the curative effect of dentin hypersensitivity. The integrated measuring system comprises a first applying module, a second applying module and a third applying module, the application force of the tactile stimulus is incremented at a preset gradient, and recording a tactile threshold of the patient representing an uncomfortable time; the second applying module applies cold air stimulation to the teeth of the patient; the temperature and the pressure of the cold air stimulation are controlled within a preset range, and the reaction score of the patient according to the Schiff cold air sensitivity scale is recorded; the association module associates the touch threshold with the reaction score to obtain comprehensive evaluation data; the acquisition module takes an initial touch threshold value and an initial reaction score obtained by measuring teeth of a patient for the first time or before treatment as baseline data; and the evaluation module obtains an evaluation result of the curative effect of the dentin hypersensitivity according to the comprehensive evaluation data and the baseline data. By simultaneously applying tactile stimulation and cold air stimulation, the one-sidedness of single stimulation evaluation is avoided, and the accuracy of evaluation of the curative effect of dentin hypersensitivity is improved.

The invention discloses application of L-theanine and a composite material thereof in preparation of a product for preventing and treating dentin hypersensitivity, and belongs to the technical field of biological medicines. The invention discloses application of L-theanine and a composite material thereof in preparation of a product for preventing and treating dentin hypersensitivity on the first aspect. On the second aspect, the invention discloses a product for preventing and treating dentin hypersensitivity. The product comprises L-theanine or / and a composite material thereof and a pharmaceutically acceptable carrier. The invention discloses a product for preventing and treating dentin hypersensitivity on the third aspect. The product comprises a medical device with a coating on the surface, the coating comprises L-theanine or / and a composite material of the L-theanine. The L-theanine is found to have the effects of mineralizing and sealing dentinal tubules and reducing nervous excitability of dental pulp for the first time, and the L-theanine is used for preventing and treating dentin hypersensitivity and has an exact effect.

The application relates to the field of biomaterials, and particularly relates to application of a giant salamander mucus extract hydrolysate in preparation of an anti-dentin sensitivity agent. The anti-dentin sensitivity agent comprises a hydrolysate retaining the biological activity of SSAD, the hydrolysate being a product of reduction of the giant salamander mucus extract by an acid solution with a pH value of 1-5, and the product comprising five active proteins, namely MHC class I molecule alpha chain, homeobox protein Hox-D13, abnormal heavy chain 3 of axonemal dynein, ATP synthase protein and cytochrome b; the particle size of the giant salamander mucus extract is 1-50 mu m; and the pH value of the anti-dentin sensitivity agent is 5.5-7.5. The giant salamander mucus extract is treated by the acid solution to obtain the hydrolysate containing the multiple active proteins, the hydrolysate can effectively promote deep closure of dentin tubules, and has long-term stable biocompatibility; the pH value is controlled to ensure that the biological activity is completely retained, and the curative effect of the anti-dentin sensitivity agent is remarkably improved.

The invention belongs to the technical field of oral care products, and particularly relates to anti-dentin hypersensitivity toothpaste and a preparation method thereof. The dentin hypersensitivity resistant toothpaste comprises the following components: fluoride, sylvite and hydrated silica, wherein the fluoride is a composition of sodium fluoride and sodium monofluorophosphate. Three anti-allergic functional components including fluoride, sylvite and hydrated silica are matched and combined, exposed dentinal tubules are blocked through the hydrated silica, sodium monofluorophosphate and sodium fluoride are combined with hydroxyapatite contained in teeth to form fluorapatite remineralization to block the dentinal tubules, meanwhile, nerve response is blocked through the sylvite, pain is relieved, and the anti-allergic effect is achieved. And the three components have a synergistic effect, so that an excellent dentin hypersensitivity resisting effect is achieved.

This invention relates to the field of oral care, and particularly to an anti-dentin hypersensitivity mineralizing solution, its preparation method, and its application. The anti-dentin hypersensitivity mineralizing solution provided by this invention, on the one hand, due to the ultra-small size of the ions and ion clusters in the solution and its fluidity, ensures effective diffusion into the dentinal tubules after being coated on the dentin surface; on the other hand, when the mineralizing solution comes into contact with saliva or bodily fluids, it produces a biocompatible mineral—strontium-containing calcium phosphate stable by polyphosphate—which can block exposed dentinal tubules; moreover, the introduced strontium ions can passivate the nerve conduction of external stimuli, thereby alleviating the symptoms of tooth sensitivity; polyphosphate also provides certain antibacterial properties; strontium ions and polyphosphate can jointly regulate the mineralization properties of the mineralizing solution. Therefore, the anti-dentin hypersensitivity mineralizing solution provided by this invention can effectively prevent and treat dentin hypersensitivity and other symptoms related to tooth demineralization.

The invention relates to a composition comprising galangin, oleic acid and adenosine. Said composition can be used as an oral care composition or as a medicament for use in the prevention from or treatment of a disease or symptoms of a disease in a subject, e.g. dentin hypersensitivity, periodontitis and / or gingivitis.

The present application belongs to the technical field of medical material preparation, and particularly relates to a dentin sensitivity desensitizer based on chitosan self-assembly and enzymatic mineralization technology and a preparation method thereof. The amorphous chitosan core-based desensitizer of the present application can not only deeply penetrate into dentin tubules, but also realize rapid mineralization through the loaded phosphatase. Compared with traditional dentin sensitivity desensitizers, the amorphous chitosan desensitizer of the present application has rapid effect and good blocking effect. The results of the examples show that the dentin sensitivity desensitizer provided by the present application can fully and effectively penetrate into the dentin tubules, can form a dense mineralized layer on the surface and inside of the dentin tubules, and the blocking depth exceeds 200 mu m.

The invention belongs to the field of washing products, and particularly relates to toothpaste capable of preventing caries, inhibiting dental plaque and resisting dentin hypersensitivity. According to the invention, the porous carbon material is prepared from corn straws by utilizing the pore channel advantages of the porous carbon material, and the carbon material is prepared into a rod-shaped structure by controlling the synthesis conditions. The prepared carbon material with the rod-like structure is beneficial to fusion of Ag-Zn antibacterial nanoparticles, and the Ag-Zn antibacterial nanoparticles can play roles in adsorbing bad breath, diminishing inflammation and resisting bacteria when being used for toothpaste. In addition, the toothpaste prepared by the invention contains honeysuckle flower, jasmine flower, ginger and orange peel which supplement each other, has a certain inhibition effect on different bacteria in the oral cavity, and can better prevent caries, inhibit dental plaque and resist dentin hypersensitivity.

The present invention relates to compositions for use in oral care and various methods of their use. In particular, it relates to compositions comprising phosphoproteins and their use in the treatment and prevention of dentine hypersensitivity and the treatment and prevention of xerostomia. Preferred compositions comprise osteopontin and derivatives thereof.