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10results about How to "Improve residency" patented technology

Dual-fermentation thick skin factor liposome, preparation method thereof and cosmetics

The invention provides a double-fermentation thick skin factor liposome, a preparation method thereof and a cosmetic, and relates to the technical field of biomedical materials. The double-fermentation thick skin factor liposome comprises alkaloid, a double-fermentation thick skin factor, phospholipid and short-chain fatty alcohol, the dual-fermentation skinning factor comprises galactose yeast fermentation liquor, lactic acid bacteria NP and glycyrrhetinic acid. According to the double-fermentation thick-skin factor liposome provided by the invention, the double-fermentation thick-skin factor has excellent anti-aging and anti-aging effects, can remarkably improve the cell activity and enhance the skin barrier, and is prepared into a liposome form, and glycyrrhetinic acid in the double-fermentation thick-skin factor and sophocarpidine are utilized to form a supramolecular eutectic. The double-fermentation thick skin factor liposome has double advantages of the supramolecular eutectic solvent and the liposome, the double-fermentation thick skin factor is efficiently promoted to enter the skin, the skin residence rate is increased, and the local treatment effect is effectively improved to play the anti-aging effect of the double-fermentation thick skin factor liposome.
Owner:SHANGHAI WORLD LEADER PHARM CO LTD +1

Drug-loaded exosomes for improving the ability of leydig cells to secrete testosterone, and preparation method and application thereof

PendingCN122251631AImprove residencyaccurate targetOrganic active ingredientsPharmaceutical non-active ingredientsDiseaseTesticular Interstitial Cells
The application belongs to the field of regenerative medicine and nano drug delivery system, and particularly relates to a drug-loaded exosome for improving the testosterone secretion capacity of testicular interstitial cells and a preparation method and application thereof. The application links a targeting FATE1 polypeptide to the surface of MSC-derived exosomes by a chemical coupling method, and loads a small molecule compound in the exosomes by electroporation, so as to obtain modified MSC-derived exosomes. The obtained exosomes can obtain the targeting capacity in testicular interstitial cells, and the natural repair capacity of MSC-derived exosomes and the release of small molecule drugs promote the repair of damaged cells, improve the testosterone secretion capacity of testicular interstitial cells, and relieve male erectile dysfunction caused by diseases or aging.
Owner:JIANGSU XINCHAO BIOTECHNOLOGY (GRP) CO LTD

Anti-aging composition liposome, preparation method thereof and cosmetics

The invention provides an anti-aging composition liposome, a preparation method thereof and cosmetics, and relates to the technical field of biomedical materials. The anti-aging composition liposome comprises betaine, xylitol, short-chain fatty alcohol, phospholipid, an antioxidant and an anti-aging composition, the anti-aging composition is prepared from CutiFine CLR, CutiGuard CLR, a cell lysis product of a fermentation product of a bifidus yeast and oleuropein. According to the anti-aging composition lipidosome provided by the invention, the betaine and the xylitol are adopted to form a deep eutectic solvent, so that the anti-aging composition lipidosome has a relatively good infiltration promotion effect, and the stability of the anti-aging composition is improved by carrying out synergistic infiltration promotion in combination with a lipidosome technology. The anti-aging composition lipidosome improves the skin residence rate, effectively improves the local treatment effect, reduces potential side effects, and enhances the stability and transdermal absorption of active ingredients, thereby playing an important role in skin care and anti-aging treatment.
Owner:SHANGHAI WORLD LEADER PHARM CO LTD +1

Injectable hydrogel for preventing esophageal benign stenosis as well as preparation method and application of injectable hydrogel

The invention discloses injectable hydrogel for preventing esophageal benign stenosis as well as a preparation method and application of the injectable hydrogel, and belongs to the technical field of biological medicines. The hydrogel comprises an exosome and a gel packaging material used for packaging the exosome, the exosome comprises overexpressed miRNA34a, and the gel packaging material comprises polydopamine and chitosan. And the gel packing material also contains an antioxidant. And the antioxidant is cerium oxide CeO2. Animal experiments find that the hydrogel preparation prepared by the invention can effectively improve the bioavailability of exosomes, improve the stability and residence rate of the exosomes in vivo, realize drug sustained release, promote the synergistic operation of wound tissue cells and cell factors, and prevent esophageal ESD postoperative stenosis. The hydrogel provided by the invention is simple and convenient to use, has a good stenosis prevention effect, and can avoid systemic side effects and the like.
Owner:THE FIRST MEDICAL CENT CHINESE PLA GENERAL HOSPITAL

Oil-based drilling fluid plugging agent and its preparation method

This invention relates to an oil-based drilling fluid plugging agent and its preparation method, comprising granular materials made of the following components by weight percentage: asphalt powder: 15-28 wt%; organic clay: 6-16 wt%; rock fiber: 25-40 wt%; nano-SiO2: 5-12 wt%; sepiolite: 8-15 wt%; elastic graphite: 8-18 wt%; and polyurethane (TPU) powder particles: 10-20 wt%. This invention features good compatibility, high efficiency, and excellent plugging effect. It can repair formation defects in the wellbore, prevent wellbore leakage, enhance the retention and plugging effect of oil-based drilling fluid in formation microfractures, improve wellbore stability, and effectively plug and strengthen the wellbore.
Owner:SINOPEC OILFIELD SERVICE CORPORATION +2

Air curtain system and control method and control device of air curtain system

The invention relates to the technical field of ventilation and air conditioning of nuclear power plants, in particular to an air curtain system, a control method and a control device of the air curtain system, and the air curtain system comprises a compressed air connection unit (10), a fan air supply unit (20), a nozzle unit (30) and a control unit (40), and the control unit (40) is used for controlling the compressed air connection unit (10) to provide compressed air for the nozzle unit (30), or controlling the fan air supply unit (20) to supply air to the nozzle unit (30), so that the nozzle unit (30) jets airflow and forms an air curtain. The air curtain system provided by the invention has relatively high use reliability, and can meet the use requirements in special scenes such as nuclear power plant reactor accident conditions and the like.
Owner:GUANGDONG NUCLEAR POWER JOINT VENTURE +3

A hazardous waste incineration system

ActiveCN224649841UImprove incineration removal rateavoid forming
The utility model discloses a harmful waste gas incineration system belongs to harmful gas processing technical field. Including combustion supporting swirl gas combustor, incinerator, combustion supporting swirl gas combustor fixed mounting at the front end hearth entrance of incinerator, its spout communicates with the hearth inside of incinerator, the tangential waste gas nozzle assembly that incinerator waste gas bellows and incinerator waste gas spout constitute is arranged in the circumference of the furnace wall of incinerator, and incinerator waste gas spout communicates with the hearth inside of incinerator, the harmful waste gas incineration system of the utility model is through the integration layout of hierarchical combustion structure design, swirl reinforced mixing, automatic precision control, has solved the traditional waste gas incineration system and mixes not fully, and the low combustion efficiency, NO x The technical problem that the generation is high, has the multiple advantages such as low nitrogen emission, high -efficient incineration, stable operation, strong adaptability.
Owner:XIAN RUIYING ENERGY ENVIRONMENTAL TECHNOLOGY DEVELOPMENT CO LTD

Electret piezoelectric sensing device and preparation method thereof

PendingCN119630259AImprove residencyincrease sensitivityPorous layerElectret
The invention discloses an electret piezoelectric sensing device and a preparation method thereof. The electret piezoelectric sensing device comprises a polarized electricity storage material layer and an electrode layer; the electricity storage material layer comprises a plurality of PTFE compact layers and at least one porous layer which are stacked and tightly combined, the porous layer is arranged between the two compact layers, and the two end faces of the porous layer are compact layers. According to the piezoelectric device provided by the invention, optimized electric field distribution is formed near the hole, a pressure change layer is generated on a bonding interface through hot pressing bonding, the molecular orientation and conformation of the interface are changed, a field plate effect is formed, the sensitive degree of polarized charges to pressure deformation can be improved under the combined effect, and the residence capability of the polarized charges is improved; therefore, by combining the PTFE composite film technology with piezoelectricity, the functional material which is high in performance, durable and suitable for complex environments is manufactured, and the functional material can stably work in severe environments such as high temperature and high corrosivity and has wide application prospects.
Owner:SHANGHAI DAGONG NEW MATERIALS

Launching and recycling system and method suitable for polar region AUV deep ice deployment

The invention discloses a laying and recycling system and method suitable for polar region AUV deep ice deployment, the laying and recycling system is an execution system composed of a traction device, a bearing cable, a laying and recycling device and the like, a main frame of the laying and recycling device is a grid-shaped rotary body made of a rubber material, and the laying and recycling device can adapt to the passing requirement of ice holes with limited sizes through compression deformation; the gyroscope, the propeller, the floating bag, the guiding equipment and other parts are arranged on the main frame, so that the underwater posture adjustment of the device and the accurate guiding of the polar region AUV are realized; when the polar region AUV needs to be recycled, the traction motor drags the rope, so that the polar region AUV is tightly sleeved with the main frame, the guide opening is contracted and closed, and the polar region AUV is recycled to the ice surface under the protection of the main frame; in the non-recovery stage, the device can provide energy supplement, information exchange and underwater parking services for the polar region AUV in the operation period, the deep ice deployment and recovery problem of the polar region AUV is effectively solved, and the residence capacity and recovery efficiency of the polar region AUV are improved.
Owner:SUN YAT SEN UNIV

Background management method and device, electronic equipment and storage medium

The invention relates to a background management method and device, electronic equipment and a storage medium. The background management method comprises the following steps: acquiring a historical use record of each application program in the electronic equipment, wherein the historical use record comprises the running probability of each application program in a foreground under different scene parameters; the priority of each application program is determined based on the historical use record, and the priority represents the probability that the application program runs in the foreground under the current scene parameter; and performing background management on the application programs based on the priorities. According to the background management method, the memory space and the hardware performance in the electronic equipment can be more reasonably utilized, the residence capability of the application program is improved, the time consumed for starting the application program is shortened, and the long waiting time when the application program is started again is avoided, so that jamming in the use process of a user is reduced, the system fluency of the electronic equipment is improved, and the user experience is improved. And the user experience is improved.
Owner:BEIJING XIAOMI MOBILE SOFTWARE CO LTD