39results about How to "Improve residency" patented technology

The present invention relates to an oral drug delivery system with biphasic release characteristics comprising a porous matrix comprising at least one drug substance, sugar(s), a release retarding polymer, gas generating components and optionally, pharma-ceuti-cally acceptable auxiliary components wherein the pharmaceutical composition further comprises a coating of said drug substance. The pharmaceutical composi-tion, either in the form of pellets (multiparticulate or single unit dosage form), beads, granules, capsules or tablets, is retained in the stomach while selectively delivering the drug(s) at gastrointestinal levels and upper parts of the small intestine over an extended period of time. The release of the drug from the said pharmaceutical composition is characterized by a biphasic release profile of the drug substance, which exhibits both immediate and controlled release characteristics.

The present invention provides a temperature resistant, non-crosslinked and biodegradable gel leak-stopping agent and a preparation method thereof. The gel leak-stopping agent of the present invention has the following advantages that: the gel leak-stopping agent has extra-wide temperature adaptability, can adapt to a temperature range of 25-180 DEG C, and can meet requirements of oil field construction; the gel leak-stopping agent has rapid dissolution rate, and forms the structure type gel with good shear thinning behavior after dissolving, wherein the structure type gel is the liquid whichcan be pumped and flow; the gel leak-stopping agent does not require cross-linking; the real fluid leak-stopping is realized; the construction is convenient; the product is completely dissolved in water, no precipitate and flocculent insoluble matter are generated during the whole process, no insoluble matter is generated after the product is degraded, such that the flow back is easy or the flow back is not required, the reservoir is not damaged; the product is safe and environmental protection, and is synthesized by the multi-stage initiation, such that the product conversion rate is high, the stability is good, no toxic damage is generated to the stratum, the production layer can be protected.

The invention discloses a high-strength multifunctional plugging agent. The plugging agent comprises, by mass, 100 parts of a structural forming agent, 0.001-15 parts of a curing agent, 0.001-10 partsof an interface adhesion agent, 0.001-200 parts of a nano filler and 0.001-30 parts of a diluent, wherein the structural forming agent comprises one or two of unsaturated polyester and vinyl resin; the curing agent comprises one or more of peroxide, persulfide and azo compounds; the interface adhesion agent comprises vinyl triethoxy silane or vinyl trimethoxy silane; the nano filler comprises oneor more of nanoscale or micron-scale carbonate, silicate and sulfate. During use, the structural forming agent, the curing agent, the interface adhesion agent, the nano filler and the diluent are mixed and react to generate liquid gel; the liquid gel is injected to a target plugged zone position and is solidified to form the high-strength multifunctional plugging agent. The plugging agent is stable in performance, good in residence property, high in adhesion force, high in elasticity modulus and high in compressive strength, and has a wide application range and good effects in oil and gas field drilling and production operation.

The invention relates to the field of drilling fluid leaking stoppage and discloses a gel particle plugging agent and a preparation method and application thereof. The gel particle plugging agent is of a nucleus-shell structure, the nucleus is made from gel particles, and the shell is made from thermoplastic resin; the gel particles are prepared through a reaction of a nonionic monomer, a crosslinking agent, an initiator, alginate, filling particles and water. The gel particle plugging agent has excellent high temperature resistance and has an excellent blocking effect on the high-temperaturedropping stratum.

Disclosed are a cell selection method, a user equipment and a storage medium, the method being applied to the user equipment, the method includes obtaining category information of LTE cells by classifying all LTE cells in which the UE resides, and further determining a residing priority of the LTE cells according to the category information, so that the UE can preferentially reside in a first typeof LTE cells according to the residing priority, therefore, it is ensured that the first type of 5G cell supporting SA can be reselected or switched to from the LTE cell subsequently through the cross-system interoperation process, the residence probability of the first type of 5G cell is improved, and due to the fact that the 5G cell supporting SA can provide more diverse and perfect network services for UE, the cell selection method can improve the network service quality of the UE.

The invention discloses a high-efficiency compound retention aid specially used for making paper and a preparation method thereof. The high-efficiency compound retention aid specially used for making paper comprises the following raw materials in weight percentage: 5%-15% of chitosan, 10%-20% of polyaluminium chloride, 10%-20% of polyaluminium chloride, 20%-30% of cationic starch and 25%-35% of cationic polyacrylamide. The preparation method comprises the following steps of: selecting the raw materials of chitosan, polyaluminium chloride, polyaluminium chloride, cationic starch and cationic polyacrylamide, then carrying out inspection, drying, coarse crushing, fine crushing, sieving, metering, high-speed stirring and mixing and compounding to obtain the retention aid. The retention aid has the advantages of less consumption, high retention rate and high cost performance and can be widely used in the fields of textile spool paper, culture paper, toilet paper, coated paper, common yellow board packaging paper and the like.

The invention discloses a preparation method for special rutile titanium dioxide used for papermaking. The preparation method is characterized by comprising the following steps: 1) sanding qualified calcined sulfuric acid-process titanium dioxide from a rotary kiln, then introducing slurry with a qualified sanding particle size into a coated tank, controlling the concentration of the slurry, in terms of TiO2, to be 250 to 350 g/L and carrying out heating to 70 to 75 DEG C; 2) adjusting the pH value of the slurry with dilute sulfuric acid to 2.0 to 3.0; 3) adding a phosphoric acid solution, wherein the concentration of the phosphoric acid solution is 250 to 300 g/L, and in terms of P2O5, the addition amount of the phosphoric acid solution accounts for 1.0 to 5.0 wt% of the total amount of TiO2; 4) adding an aluminum salt solution to adjust a pH value to 6.0 to 7.5 and carrying out curing for 60 min with the pH value maintained; 5) adding the metered aluminum salt solution and a corresponding neutralizing reagent, maintaining the pH value of the slurry to be 5.0 to 6.5 and carrying out curing for 2 h after completion of addition; and 6) carrying out washing three times, flash evaporation and jet milling.

The invention relates to the technical field of medicines, in particular to application of rapamycin in preparation of a miscarriage prevention medicine for spontaneous abortion. Compared with normalpregnancy, macrophages residing in decidua tissue of a patient suffering from recurrent spontaneous abortion are reduced, and expression of adhesion molecules is low; and the autophagy level of the decidual macrophages of the abortion patient is low. Experimental results show that the rapamycin can significantly promote adhesion of the macrophages to decidua matrix cells. Normal pregnant rats andabortion pregnant rat models are constructed, and in-vivo experiments prove that: the rapamycin is applied to reduce dwelling of decidual macrophages caused by autophagy disorders, maintains the steady state of decidua immune components and significantly reduces the embryo absorption rate of the pregnant rats, thereby improving the outcome of bad pregnancy. Therefore, the rapamycin is expected tobe used as the miscarriage prevention medicine for spontaneous abortion, a new treatment scheme is provided for patients suffering from repeated spontaneous abortion, the psychological burden of the patients is relieved, and the rapamycin can be well applied clinically.

The invention discloses a redirecting method and device, and the method comprises the steps: obtaining the identification of user equipment, wherein the user equipment currently stays in a first network; judging whether the identification of user equipment is located in a blacklist or not, wherein the blacklist stores the identification of user equipment which does not support the redirecting to a second network in a connection state of a first network; transmitting a wireless resource control connection releasing message to the user equipment when the identification of user equipment is located in the blacklist, wherein the wireless resource control connection releasing message comprises an adjacent frequency point information of the second network, and is used for triggering the user equipment to return to an idle state from the connection state of the first network, so that the user equipment searches the second network in the idle state according to the adjacent frequency point information and is redirected to the second network. Therefore, the method can improve the probability that the user equipment which can be redirected to the second network in the idle state according to the needs is redirected to the second network.

The invention provides a temperature-sensitive adhesion type resin plugging agent as well as a preparation method and application thereof. The temperature-sensitive adhesion type resin plugging agent comprises the following raw materials in parts by mass: 75-90 parts of a thermoplastic resin matrix, 5-15 parts of a melting temperature regulator, 2-8 parts of an organic lipid melting range regulator, 0.5-6 parts of a modified solid-phase filling melting range regulator and 0-30 parts of a modified density regulator. According to the temperature-sensitive adhesion type plugging agent disclosed by the invention, different types of thermoplastic resins are taken as matrixes, when the temperature reaches the melting point of plugging agent particles in a water phase, the surfaces of the plugging agent particles start to melt and have certain viscosity, the plugging agent particles can be mutually adhered, and the plugging agent particles can also be adhered to the wall surface of a drilling fluid leakage channel; the retention capacity of the plugging agent in a leakage channel is enhanced, the overall strength of the plugging agent among particles of a plugging layer is improved, the plugging agent is not prone to being influenced by pressure fluctuation, the one-time plugging success rate is increased, and re-leakage is effectively avoided.

The invention provides a plugging agent, which comprises, by weight, 100 parts of water, 5-20 parts of a curing agent, 1-6 parts of an activator, 1-5 parts of a gelatinizing agent, and 40-120 parts ofa structural base material, wherein the curing agent is silicate, and the gelatinizing agent is an aluminum salt. Compared with the plugging agent in the prior art, the plugging agent of the invention has the following characteristics that the silicon-aluminum gel formed by the silicate and the aluminum salt is used as the base slurry, the free water can be bound in the whole gel system structureso as to reduce the content of the free water and improve the viscosity of the gel system, and the liquid filtered out in the plugging process contains high-concentration silicate ions so as to reactwith the formation water and various minerals in the stratum to strengthen the plugging effect; the activator reacts with the structural base material to form a high-strength solidifying body, and the curing agent and the gelatinizing agent participate in the solidification reaction, so that the plugging agent filtrate, the filter cake and the plugging agent can participate in the solidificationand cementation of the leakage channel and the stratum rock mass so as to increase the plugging treatment radius; and the plugging agent is wide in density adjustment range.

The invention provides a temperature-sensitive adhesion type bridging leaking stoppage system, leaking stoppage slurry and a preparation method and application of the leaking stoppage slurry. The temperature-sensitive adhesion type bridging leaking stoppage system is characterized by being prepared from the following raw materials in percentage by mass: 20 to 50 percent of temperature-sensitive adhesion type resin particles, 20 to 30 percent of rigid particle materials, 20 to 30 percent of elastic particle materials and 10 to 20 percent of fiber materials. The invention also provides a preparation method of the leaking stoppage slurry, which comprises the following steps: adding the temperature-sensitive adhesive resin particles, the rigid particle material and the elastic particle material into clear water or drilling fluid, and stirring at a high speed until the materials are uniformly dispersed; and then adding the fiber material, and stirring at a low speed until the fiber material is uniformly dispersed to obtain the temperature-sensitive adhesion type bridging leaking stoppage slurry. The leaking stoppage slurry provided by the invention is high in one-time leaking stoppage success rate, effectively avoids re-leakage, and overcomes the problems that a stacked leaking stoppage layer formed by a conventional bridging leaking stoppage material in a crack is low in strength and is easily influenced by pressure fluctuation to cause leaking stoppage failure.

The invention discloses a purification particle, which comprises a carrier and a viscous coating which is loaded on the carrier and has a pollutants degradation function. The purification particle has a microporous structure. With the microporous structure, contact area between solids and pollutants is increased, and the purification particle has stronger pollutants adsorption capacity. In addition, pollutants can be left in the microporous structure and can be prevented from overflowing. Concentration of pollutants in the microporous structure is increased, the viscous coating has faster speed of degrading pollutants, and purification is more thorough. Thereby, purification efficiency of the purification particle is enhanced.

The invention discloses a bridge plugging synergist for drilling fluid. The bridge plugging synergist comprises the following components in percentage by mass: 20-40% of wood fibers, 35-40% of inorganic mineral fibers, 20-30% of inorganic rigid particles and 5-10% of an inorganic reinforcing agent. The inorganic rigid particles are resin sand with the particle size of 200 meshes or a compound of the resin sand and ceramic powder; the inorganic mineral fiber is a combination of brucite fibers, aluminum silicate fibers and carbon fibers, wherein the brucite fibers are 1-3 mm in length and 0.5-16[mu] m in diameter, the aluminum silicate fibers are 2-4 mm in length and 0.7-20 [mu] m in diameter, and the carbon fibers are 1-4 mm in length and 0.5-18 [mu] m in diameter; wherein the mass ratio of the brucite fibers to the aluminum silicate fibers to the carbon fibers is 5: 4: 1. According to the bridge plugging synergist disclosed by the invention, through the cooperative use of the microfibers and the microparticles, microcracks can be effectively plugged, and the compactness of a bridge plug is improved, so that the pressure bearing capacity is enhanced.

The invention provides a transfer buffer for promoting residence of small molecular proteins on a PVDF membrane, wherein the transfer buffer uses 8-20% isopropanol as a PVDF membrane activator, simultaneous detection of small-molecule proteins and macromolecular proteins can be carried out only by using the uniform 0.45[mu]M PVDF membrane, and a new transfer solution formulation is verified by optimally searching the type and concentration of PVDF membrane activators, that is, 8-20% isopropanol used as a wet transfer buffer of 0.45[mu]M PVDF membrane can improve the resident effect of small molecular proteins, and has high repeatability, good retention effect, simple operation, broad application prospect and great market value.

The embodiment of the invention provides a voice service switching method and device, electronic equipment and a storage medium, and relates to the technical field of wireless communication and terminals. The voice service switching method comprises the following steps: in a VoWiFi (Voice over Wireless Fidelity) call process, monitoring a characteristic parameter used for representing VoWiFi call quality; if it is judged that a triggering condition for network search is met based on the feature parameters, searching for a long term evolution (LTE) network to obtain a search result; selecting a target LTE network to be resided according to the search result; judging whether a WiFi network used by the VoWiFi call and the target LTE network meet a switching condition of switching to the VoLTE call or not; and if the switching condition is satisfied, switching from the VoWiFi call to the VoLTE call, so that the terminal leaves the 5G SA network. According to the scheme, the residence rate of the 5G SA network can be improved when VoWiFi is seamlessly switched to VoLTE, so that the use experience of a user on the 5G SA is improved.

The invention discloses a passive emergency air conditioning device of a master control room for a nuclear power plant. A compressed air storage tank is communicated with a vortex tube; the vortex tube is provided with a cold air outlet and a hot air outlet, the cold air outlet of the vortex tube is communicated with the heat exchange component through a cold air pipeline, and the heat exchange component is installed on the cooling beam which is hollow and communicated with the heat exchange component. Under the working condition of completely losing alternating current power supply design expansion, heat exchange between cold air and hot air in a main control room is achieved, cooling and fresh air supply functions are completed, and the hot air curtain is used for being installed at an inlet and an outlet of the main control room. A hot air outlet of the vortex tube communicates with a hot air curtain through a hot air pipeline; the micro iodine adsorber is connected to the hot air curtain, the hot air curtain covers the micro iodine adsorber, and the vortex tube separates hot air and purges the micro iodine adsorber through the hot air curtain, so that the relative humidity of the micro iodine adsorber is ensured, the purification efficiency is ensured, the purification function of the main control room is realized, the residence of the main control room under the working condition of power failure of the whole plant is practically improved, and the inherent safety of the power station is improved.

The invention provides a preparation method of a high polymer modified rubber leaking stoppage material for leaking stoppage of oil-based drilling fluid. The preparation method comprises the following steps: mixing a high polymer containing active groups, rubber, a solvent, an oil-soluble cross-linking agent and an oil-soluble initiator, heating to react, and granulating to obtain a weak cross-linked high polymer for leaking stoppage of oil-based drilling fluid, wherein the high polymer containing active groups is one or more of polybutadiene, polyisoprene, polybutadiene-styrene, polyacrylonitrile-butadiene-styrene and the like. A high polymer containing active groups is adopted to modify common rubber to form a core-shell structure product, common rubber powder is taken as a core, and the high polymer is taken as a shell. The high polymer shell can absorb oil and become sticky in an oil phase environment at 80-120 DEG C, has good cohesiveness, and improves the residence capacity of the rubber by bonding leakage layer rock and other leakage stopping materials. The modified rubber is in a solid state at normal temperature, has small influence on the rheological property of the oil-based drilling fluid, and can be conveniently pumped to a leakage layer.

The invention provides a preparation method of a weak cross-linked high polymer for oil-based drilling fluid leakage stoppage. The preparation method comprises the following steps: mixing a high polymer containing active groups, an oil-soluble cross-linking agent, an oil-soluble initiator and a solvent, heating to react, and granulating to obtain the weak cross-linked high polymer for oil-based drilling fluid leakage stoppage, wherein the high polymer containing active groups is one or more of polybutadiene, polyisoprene, polybutadiene-styrene, polyacrylonitrile-butadiene-styrene and the like. According to the invention, a modified material of a high polymer containing active groups is adopted, and the elastic deformation of the material is improved through crosslinking modification on the basis of the oleophylic cohesiveness of the high polymer. At the leakage layer temperature, the non-crosslinked part of the high polymer gradually absorbs oil and becomes sticky, so that the residence property of the leaking stoppage material in an oil phase can be improved; and a cross-linked part is still in a rubber state, has elastic deformation, and is beneficial to blocking pores with different particle sizes. Under the pressure of a leakage layer, the high polymer particles are adhered together, so that the damage resistance of a plugging layer is improved.

The embodiment of the invention provides a cell residence method, a terminal and a storage medium, and the method comprises the steps: obtaining a previous residence cell under the condition that a current residence cell receives a cell switching instruction sent by a network side, counting data transmission parameters of a packet data convergence protocol (PDCP) layer corresponding to the last resident cell in the execution process of the first service; the terminal executing the first service in the previous resident cell and the current resident cell; according to the PDCP layer data transmission parameters, determining an abnormal rate of a previous resident cell; and if the abnormal rate is greater than a preset abnormal rate threshold, forbidding switching to the previous resident cell.