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Malus toringoides fruit extract and pharmaceutical application thereof

A kind of extract, the technology of russa fruit, which is applied in the field of russa fruit extract and its pharmaceutical application, to achieve good anti-oxidation function, inhibit growth, and simple extraction process

Pending Publication Date: 2022-05-06
SICHUAN ZHIJIACHENG BIO TECH CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] But, also do not see the report of the medicament for the preparation treatment gastric cancer of russia fruit or its extract at present

Method used

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  • Malus toringoides fruit extract and pharmaceutical application thereof
  • Malus toringoides fruit extract and pharmaceutical application thereof
  • Malus toringoides fruit extract and pharmaceutical application thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0023] Embodiment 1, the preparation of Russian fruit extract of the present invention

[0024] Accurately weigh 1g of Eseguo medicinal material powder, then add 10mL of 60% ethanol, reflux extraction for 1 hour; filter to obtain the first filtrate and filter residue; add 10mL of 60% ethanol to the filter residue, reflux extraction for 1 hour, filter to obtain The second filtrate and filter residue. Merge the two filtrates to obtain the Russian fruit extract.

Embodiment 2

[0025] Embodiment 2, the preparation of Russian fruit extract of the present invention

[0026] Accurately weigh 1g of Eseguo medicinal powder, then add 20mL 60% ethanol, reflux extraction for 1 hour; filter to obtain the first filtrate and filter residue; add 20mL 60% ethanol to the filter residue, reflux extraction for 1 hour, filter to obtain The second filtrate and filter residue. Merge the two filtrates to obtain the Russian fruit extract.

Embodiment 3

[0027] Embodiment 3, the preparation of Russian fruit extract of the present invention

[0028] Accurately weigh 1g of Russian fruit medicinal material powder, then add 30mL 60% ethanol, reflux extraction for 1 hour; filter to obtain the first filtrate and filter residue; add 30mL 60% ethanol to the filter residue, reflux extraction for 1 hour, filter to obtain The second filtrate and filter residue. Merge the two filtrates to obtain the Russian fruit extract.

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Abstract

The invention discloses a malus toringoides fruit extract and pharmaceutical application thereof. The preparation method of the malus toringoides fruit extract comprises the following steps: taking malus toringoides fruits, extracting with 50-80% ethanol as an extraction solvent, filtering, and taking filtrate to obtain the malus toringoides fruit extract. Experiments show that the malus toringoides fruit extract not only can effectively inhibit the growth of gastric cancer cells, but also has a good antioxidant function, and also has a good protective effect on liver injury caused by CC14. Therefore, the malus toringoides fruit and the malus toringoides fruit extract have very good application prospects in preparation of medicines for preventing and / or treating gastric cancer, medicines or health care products for protecting liver injury and medicines or health care products for resisting oxidation.

Description

technical field [0001] The invention belongs to the field of traditional Chinese medicine extracts, and in particular relates to an extract of russa fruit and its pharmaceutical use. Background technique [0002] Russe fruit is the dry mature fruit of Rosaceae plants Malus toringoides (Rehd.) Hughes. and Malus transitoria (Batal.) Schneid. In the Tibetan area of ​​Ganzi, Russian fruit is commonly known as Waduo, Hongwaduo, Baiwaduo, etc. In addition, it is also called Dabaishizao, Xiaobaishizao, Astringent Zaozi, etc. in Gansu, and Huaye Duli (northern Shaanxi) Alias, such as madur pear, thin and weak crabapple. It is recorded in "Xinxiu Jingzhu Materia Medica", "Zhonghua Tibetan Materia Medica" and "Tibetan-Chinese Dictionary". "Etc. [0003] Erseguo has a long history of medicinal use in Tibetan areas, but there are few studies on its modern pharmacological effects. Chinese patent application CN105878449A discloses the use of a Russian fruit extract in the preparation ...

Claims

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Application Information

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IPC IPC(8): A61K36/73A23L33/105A61P35/00A61P39/06A61P1/16A61K131/00
CPCA61K36/73A61P35/00A61P39/06A61P1/16A23L33/105A61K2236/333A61K2236/39A61K2236/53A61K2236/51A23V2002/00A23V2200/308A23V2250/21A23V2300/14
Inventor 罗枫
Owner SICHUAN ZHIJIACHENG BIO TECH CO LTD
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