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Anti-coagulation nano silver antibiotic dressing

A nano-silver antibacterial and nano-silver technology is applied in the field of anti-aggregation nano-silver-containing antibacterial dressings and anti-aggregation nano-silver antibacterial dressings

Inactive Publication Date: 2004-02-11
SHENZHEN TSINGHUA YUANXING NANO MATERIAL CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Although the patent application does not indicate that there is a reduction reaction, the raw material used is AgNO 3 (Ag + ) and the finished product is nano-scale silver powder (Ag 0 )

Method used

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  • Anti-coagulation nano silver antibiotic dressing
  • Anti-coagulation nano silver antibiotic dressing
  • Anti-coagulation nano silver antibiotic dressing

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0061] Embodiment 1 prepares liquid medicine by following amount (by 10 kilograms of fabrics)

[0062] Formulation A, AgNO 2 0.3M, NH 2 ·H 2 O 0.15M, NaOH 0.1M plus deionized water to a total volume of 50 liters; formulation B glucose 4M, HNO 3 0.1M, boil for 1-5 minutes, add ethanol after cooling to make 10M, the volume is 5 liters;

[0063] Mix 10 parts of formulation A + 1 part of formulation B (V / V) and place it for 10-40 minutes, then it can be used for spraying 10 kg of cotton fabrics. After spraying, mix the liquid medicine and cotton fabrics evenly, and enter Reactor, continuously add dispersant (OP-10), oxidant (under fully ventilated conditions) to carry out chemical and physical treatment, until the fabric is brownish yellow, then through cleaning, centrifugal dehydration, drying to obtain the anti-aggregation nano-silver of the present invention Antibacterial dressings. Wherein the silver oxide content is 40%. The particle size of the nano-silver composite ...

Embodiment 2

[0065] Prepare the liquid medicine according to the following amount (based on 10 kg of fabric)

[0066] Formulation A: AgNO 3 0.1M, NH 2 ·H 2 O 0.08M, NaOH 0.05M plus deionized water to a total volume of 50 liters;

[0067] Formulation B: Ascorbic acid 0.12M, HNO 3 0.11M, boil for 1-5 minutes, add ethanol after cooling to make 6M, volume is 5 liters;

[0068] Mix 10 parts of formulation A + 1 part of formulation B (V / V) and place it for 10-40 minutes, then it can be used for spraying 10 kg of gauze. After spraying, mix the liquid medicine and gauze evenly and put it into the reaction kettle , add sodium dodecylbenzenesulfonate as dispersant, oxidizing agent (under ventilating), heat insulation, to gauze thing is brownish-yellow, then through cleaning, centrifugal dehydration, drying promptly obtains the silver antibacterial of anti-aggregation nanometer of the present invention dressing. Wherein the silver oxide content is 60%. The particle size of the nano-silver co...

Embodiment 3

[0069] Embodiment 3 prepares liquid medicine by following amount (calculated by 10 kilograms of carriers)

[0070] Formulation A: AgNO 3 0.5M, NH 3 ·H 2 O 0.3M, NaOH 0.1M, add deionized water to a total volume of 50 liters;

[0071] Formulation B: Glucose 4M, HNO 3 0.1M, boil for 1-5 minutes, add ethanol after cooling to make 10M, the volume is 5 liters.

[0072] Wash the rushes, add 98% medical alcohol and distilled water (the ratio of the two is 1:15), soak the rushes, vacuum extract until the rushes are free of water-soluble organic components and impurities, and dry to obtain solid rushes.

[0073] Mix 10 parts of A+1 part of B (V / V) and let stand for 30 minutes before dipping. Put 10 kg of processed rushes into it. After impregnation, pressurize and homogenize to mix the liquid medicine and the carrier evenly, enter the reaction kettle, add the dispersant OP-10 and oxidant continuously under the condition of ventilation and proper stirring, and heat to 150°C until ...

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Abstract

The present invention relates to antibiotic dressing for treating injury of mammal, especially human body, and is especially a kind anti-coagulation nano silver antibiotic dressing prepared via anti-coagulation technology. The antibiotic dressing includes a kind of fabric and composite nano silver particles deposited onto the fabric, and the composite nano silver particles in the size of 1-100 nm are attached firmly between the fiber elements and on the fiber. The composite particles have core of metal silver and surface layer of silver oxide, which accounts for 10-80 wt% of the whole composite particles, and the silver content of the dressing is less than 50 microgram each squared millimeter.

Description

technical field [0001] The invention relates to an antibacterial dressing for mammals, such as humans, for wounds, more specifically, to an anti-accumulation nano-silver antibacterial dressing, especially an anti-accumulation nano-silver antibacterial dressing prepared by anti-aggregation technology. Background technique [0002] Currently, wound dressings widely used in hospitals and commercially available are generally of the impregnated type. For example, medical gauze is soaked in antibacterial liquid such as geeramine and furan drugs prepared in a certain proportion. These wound dressings, due to the stability of their medicines, their products lose their medicinal properties after a certain period of time, and cannot or cannot play the therapeutic effect very well, and generally can only play a protective role to wounds. Therefore, it is very necessary to provide a dressing that can heal the wound site while protecting the wound, so that the wound site can heal quickl...

Claims

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Application Information

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IPC IPC(8): A61F13/02A61L15/00D06M11/00
Inventor 朱红军朱骊
Owner SHENZHEN TSINGHUA YUANXING NANO MATERIAL CO LTD
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