Pazufloxacin methane-sulfonate eye ointment and its producing process-anti-infection

A preparation technology of pazufloxacin mesylate, which is applied in the field of pharmaceutical preparations and its preparation, can solve the problems of long-term toxicity and reproductive toxicity, and achieve the effect of stable and controllable quality

Inactive Publication Date: 2004-04-28
HONGYI SCI & TECH CO LTD NANCHANG
View PDF0 Cites 0 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0086] 3. Toxicology
[0089] (2) Long-term

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Examples

Experimental program
Comparison scheme
Effect test

Embodiment Construction

[0125] prescription:

[0126] Pazufloxacin mesylate 6.51g (calculated as 5g by Pazufloxacin)

[0127] Add eye ointment base to 100g

[0128] Preparation Process:

[0129] Take pazufloxacin mesylate for injection and sterilized ophthalmic ointment base, thoroughly grind them evenly, and pack them separately to obtain the product.

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to view more

PUM

No PUM Login to view more

Abstract

The present invention relates to pazufloxacin methane-sulfonate eye ointment as a kind of quinolone antibiotic and its preparation process. It is eyeí»s ointment preparation prepared with pazufloxacin methane-sulfonate as active component and proper eye ointment matrix.

Description

technical field [0001] The invention relates to a pharmaceutical preparation and a preparation process thereof, in particular to a quinolone antibiotic pazufloxacin mesylate eye ointment and a preparation process thereof. technical background [0002] Quinolones are a relatively new class of synthetic antibacterial drugs. They are different from other antibacterial drugs. They target bacterial DNA and prevent bacterial DNA from forming supercoils by preventing DNA topoisomerase II and IV from functioning. , further causing irreversible damage to chromosomes, resulting in the inability of bacterial cells to divide and reproduce. It has a selective toxic effect on bacteria. Bacteria's resistance to many antibiotics can be widely spread due to plasmid transfer, but quinolones are not easily affected by plasmid transfer resistance, so there is no cross-resistance with many antibacterial drugs. The antibacterial spectrum of quinolones is constantly broadening, from a single nar...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to view more

Application Information

Patent Timeline
no application Login to view more
IPC IPC(8): A61K9/06A61K31/5365A61P27/02
Inventor 刘孝乐刘智钱进许军彭红朱丹
Owner HONGYI SCI & TECH CO LTD NANCHANG
Who we serve
  • R&D Engineer
  • R&D Manager
  • IP Professional
Why Eureka
  • Industry Leading Data Capabilities
  • Powerful AI technology
  • Patent DNA Extraction
Social media
Try Eureka
PatSnap group products