8 results about "Quinolone antibiotic" patented technology

A method for preparing and applying copper chloride-modified vinegar residue biochar, belonging to the field of wastewater treatment technology, is disclosed. The method involves: weighing 1.0000 g ± 0.0005 g of vinegar residue powder and adding it to 40 mL of ultrapure water, dispersing it thoroughly under magnetic stirring; then adding 0.5000 g of CuCl₂·2H₂O, mixing, and continuously stirring magnetically at room temperature for 24 h to allow the CuCl₂ to form a biochar. 2+ The mixture is thoroughly impregnated with vinegar residue to form a mixture. The mixture is then dried in an oven and transferred to a tube furnace. Inside the tube furnace, under a N₂ atmosphere, the temperature is increased to 600°C at 8°C / min and pyrolyzed for 120 min. After cooling, the product is removed, ground, and then copper chloride-modified vinegar residue biochar is obtained. This invention features a simple process flow, controllable operating conditions, low equipment requirements, good repeatability, and suitability for large-scale preparation. The obtained copper chloride-modified vinegar residue biochar exhibits excellent adsorption and degradation performance of organic pollutants, particularly efficient degradation and removal of quinolone antibiotics such as ciprofloxacin and norfloxacin.

The embodiment of the present application provides a Fe3O4@COF electrochemical sensor based on a covalent organic framework, a preparation method and application, the electrochemical sensor comprises: a base electrode which is surface-modified with a solid film; the solid film is a Fe3O4@COF composite material; the Fe3O4@COF composite material comprises: a core formed by a porous structure of Fe3O4 and a COF shell layer attached to the surface of the core; the COF shell layer is a covalent organic framework layer formed by copolymerization of aromatic aldehyde compounds and polyamino aromatic compounds. The Fe3O4@COF electrochemical sensor based on the covalent organic framework, the preparation method and the application can detect quinolone antibiotic molecules such as norfloxacin, and the detection limit can reach 1.927*10 ‑ 13 mol / L; and can be widely applied to the detection of quinolone antibiotics such as norfloxacin in milk and environmental water samples.

The application discloses a MOF / MIP / QCM sensor for in-situ detection of quinolone antibiotics, a preparation method and application, and belongs to the technical field of environmental antibiotic detection. The preparation method is as follows: 1) quinolone antibiotic template molecules and functional monomers are added to an organic solvent, and after being dissolved, MOF materials, a crosslinking agent and an initiator are sequentially added to obtain a prepolymerization solution; 2) the prepolymerization solution is subjected to a polymerization reaction under the protection of an inert gas, and after the template molecules are removed by washing, the MOF-based molecularly imprinted polymer is dried to obtain the MOF / MIP / QCM sensor. The sensor is connected with a quartz crystal microbalance detection device, and then placed in a water body to be detected; the specific adsorption of the sensor to quinolone antibiotics causes the characteristic of a decrease in the resonance frequency of the quartz crystal, and the in-situ rapid quantitative detection of quinolone antibiotics is realized by measuring the frequency change.

To provide a novel antimicrobial product that enables the management of animal diseases while reducing reliance on conventional antibiotics. [Solution] The present invention relates to an antimicrobial composition comprising an extract of a coffee composition and an antibiotic, and to the use of the antimicrobial composition in the manufacture of antimicrobial drugs. The extract of the coffee composition comprises a solid component and water, the solid component comprising coffee beans and auxiliary materials. The antibiotic is selected from the group consisting of penicillin antibiotics, cephalosporin antibiotics, fluoroquinolone antibiotics, tetracycline antibiotics, chloramphenicol antibiotics, aminoglycoside antibiotics and combinations thereof, and the weight ratio of the coffee composition to the antibiotic is from 1.5:1 to 25000:1. The antimicrobial composition of the present invention can exhibit a superior antibacterial effect compared to the use of antibiotics alone, and this antibacterial effect can also be exerted against drug-resistant bacteria.

This invention provides a nano-gold-modified mesoporous MXene material, its preparation method, and its application, belonging to the field of detection and testing technology. This invention employs a high redox potential difference-driven oxidation strategy to prepare uniformly mesoporous Ti3C2T. x The material was cross-linked with PDDA; gold nanoparticles were attached to mesoporous Ti3C2T x On the membrane surface, mesoporous MXene material modified with gold nanoparticles was obtained. Using the specific preparation conditions of this invention, mesoporous Ti3C2T... x Effective combination with nano-gold, gold substrate and Ti3C2T x The markers can exert a synergistic enhancement effect on SERS, which can improve the detection sensitivity and realize the function of surface-enhanced Raman spectroscopy for solid-phase substrate determination. This is beneficial for the detection of quinolone antibiotics such as ciprofloxacin in agricultural products and food, and provides semi-quantitative detection results.

The application provides a method for evaluating the phytotoxicity of quinolone antibiotics and application thereof, and relates to the technical field of pollutant toxicity evaluation. The evaluation method comprises the following steps: the Chinese cabbage seeds are sowed in a culture solution containing quinolone antibiotics for culture, and the phytotoxicity of the quinolone antibiotics is evaluated according to the physiological indexes of early growth of the seeds. The method can efficiently and simply evaluate the phytotoxicity of different generations of quinolone antibiotics, has universal applicability to quinolone antibiotics, and can effectively evaluate the phytotoxicity of low-concentration quinolone antibiotics and has high sensitivity.

The application belongs to the technical field of agricultural product variety identification, and particularly relates to a bimetallic loaded two-dimensional nanosheet and application thereof. x The nanoparticles achieve the purpose of completely degrading BPA in water by activating persulfate. x The CuCo@Ti3C2T prepared by the application has good catalytic activity when used for activating persulfate to treat quinolone antibiotics in water, can stimulate the activity of persulfate, and realizes efficient degradation of quinolone antibiotics. In addition to the above-mentioned quinolone antibiotics, the application can also be applied to degradation of other refractory organic pollutants in water.