Coumarin acetate drip pill and its preparation method
A technology of coumarin and acetic acid, which is applied in pill delivery, active ingredients of heterocyclic compounds, blood diseases, etc., can solve problems affecting the therapeutic effect of coumarin acetate, slow disintegration of tablets, and large amount of excipients, etc. And the effect of convenient taking, fast disintegration and dissolution, and reduced dosage of excipients
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example 1
[0022] prescription:
[0023] Coumarin Acetate 1g
[0024] Macrogol 6000 19g
[0025] Makes 1000 capsules
[0026] Preparation method: Take coumarin acetate fine powder that has been ultrafinely pulverized and passed through a 200-mesh sieve, add it to the molten polyethylene glycol 6000 matrix, stir well, use simethicone oil as a coolant, make pellets by dropping, dry, and have to.
example 2
[0028] prescription:
[0029] Coumarin Acetate 1g
[0030] Macrogol 4000 19g
[0031] Makes 1000 capsules
[0032] Preparation method: Take coumarin acetate fine powder that has been ultrafinely pulverized and passed through a 200-mesh sieve, add it to the molten polyethylene glycol 4000 matrix, stir well, use simethicone oil as a coolant, make pellets by dropping, dry, and have to.
example 3
[0034] prescription:
[0035] Coumarin Acetate 1g
[0036] Macrogol 6000 9g
[0037] Macrogol 4000 10g
[0038] Makes 1000 capsules
[0039] Preparation method: Take the coumarin acetate fine powder that has been ultrafinely pulverized and passed through a 200-mesh sieve, add it to the molten polyethylene glycol 4000 and polyethylene glycol 6000 matrix, stir well, and use simethicone oil as a coolant. Drop system into legal pills, dry, and get it.
[0040] 4. Example 4
[0041] prescription:
[0042] Coumarin Acetate 1g
[0043] Glyceryl monostearate 19g
[0044] Makes 1000 capsules
[0045] Preparation method: Take the coumarin acetate fine powder that has been ultrafinely pulverized and passed through a 200-mesh sieve, add it to the molten glyceryl monostearate base, mix well, use ice water as the coolant, make pellets by drop method, and dry to obtain .
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