Xuefu ecchymosis eliminating pills and their preparation

A Xuefu Zhuyu and prescription technology, which is applied in the field of Xuefu Zhuyu Pills and its preparation, can solve problems such as low quality standards, inability to meet the needs of medication, and difficulty swallowing, so as to meet the needs of medication, enrich the variety of medication, and improve product quality Effect

Inactive Publication Date: 2004-12-08
毛友昌
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

During the production process of this medicine, nearly half of the medicinal materials are powdered, which leads to large dosage and difficulty in swallowing; secondly, fine powder such as angelica is added to thick paste such as rehmannia glutinosa, granulated and dried, and the volatile components are easy to lose, and the dosage form is single. It is far from meeting people's drug needs, and its quality standards are low and there are no quantitative indicators

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0038] Example 1: Take 11 medicines in the prescription and pass the inspection respectively for later use; take peach kernel (1 / 2 of the prescription quantity), angelica, red peony root, Citrus aurantium, Chuanxiong, Bupleurum and grind them into fine powder, and the remaining 5 medicinal materials such as safflower and peach kernels (1 / 2 of the prescription amount) are decocted with water for 3 times, each time for 2 hours, the filtrate is combined, filtered, the filtrate is concentrated to a relative density of 1.05-1.15 (60°C), spray-dried to make a dry cream powder, and added The above-mentioned fine powder and appropriate amount of auxiliary materials are mixed evenly, pelletized, dried, and coated.

Embodiment 2

[0039] Embodiment 2: Get 11 flavors of medicines in the prescription to pass the inspection respectively for later use; get peach kernel, angelica, red peony root, citrus aurantium, Chuanxiong, Bupleurum, and safflower and pulverize them into coarse powder, use 70-75% ethanol as solvent, and reflux extract 2 1.5 hours each time, recover the ethanol from the extract and concentrate to an appropriate amount; decoct the dregs and the remaining licorice and other 4 herbs with water for 3 times, 2 hours each time, combine the filtrate, filter, concentrate the filtrate to an appropriate amount, and mix with the above alcohol The extracts are combined, concentrated to a relative density of 1.05-1.15 (60°C), spray-dried to make a dry cream powder, mixed with an appropriate amount of auxiliary materials, pelletized, dried, and coated.

Embodiment 3

[0040] Example 3: Take the 11 herbs in the prescription and pass the inspection respectively for use; take the 11 herbs in the prescription and grind them into coarse powder, add water and cook them for 3 times, and collect the volatile oil and cooking liquid for later use; the above-mentioned volatile oil is clathrated with β-cyclodextrin ; The above water cooking liquid is filtered, concentrated to a relative density of 1.05-1.15 (60°C), spray-dried to make a dry cream powder, mixed with the above-mentioned β-cyclodextrin inclusion compound of volatile oil and appropriate amount of auxiliary materials, pelletized, and dried , coated, that is.

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PUM

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Abstract

A Chinese medicine 'Xuefu Zhuyu pill' for promoting blood circulation, removing blood stasis and stagnant heat, and treating insomnia, headache and thoracalgia is an improvement to existing relative medicine in the form of capsule. Its preparing process is also disclosed. Its advantages are high curative effect, high release speed and high biologic utilization rate.

Description

technical field [0001] The invention relates to the technical field of making Chinese patent medicine pills, in particular to Xuefu Zhuyu Pills and a preparation method thereof. Background technique [0002] Pills are a traditional dosage form. Due to the rapid development of modern science and technology, the continuous upgrading of pharmaceutical machinery and equipment, the advent of new pill-making machines and the wide application of new excipients have given youthful vitality to the ancient dosage form of traditional Chinese medicine pills. It has changed people's traditional prejudice of "black, big and thick" traditional pills, and the pills produced by it have the advantages of fast drug release, high bioavailability, accurate dosage, easy to take, carry, and beautiful appearance. According to the relevant drug laws and regulations of our country, changing the dosage form is regarded as a new drug research, and the original dosage form of Xue...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K9/20A61P25/04A61P25/20A61P29/00
Inventor 毛友昌毛晓敏
Owner 毛友昌
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