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Antiphlogistic cholagogic pill and preparing method thereof

A technology of Lidan Pill and Andrographis paniculata, which is applied in the fields of pill delivery, digestive system, and medical formula, can solve problems such as unsatisfactory medication needs, difficulty in swallowing, and large dosage, and achieve perfect and reasonable production process, improved stability, and high quality. The effect of raising standards

Inactive Publication Date: 2004-12-08
毛友昌
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

The dosage of the tablet is large, it is difficult to swallow, and its quality standard can be further improved; meanwhile, the dosage form is single, which is far from meeting people's medication needs

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0035] Embodiment 1: The three kinds of medicines are cleaned separately, remove impurity, pass the inspection and set aside. Take andrographis paniculata and bitter wood and crush them into coarse powder, respectively use 80-85% ethanol as solvent, heat and reflux to extract twice, each time for 2 hours, and filter the extract for later use; Hours, combined decoction, filtered, the filtrate was concentrated to an appropriate amount, added 70% 7 alcohol 5 times the amount of ethanol precipitation, left standstill, filtered, the filtrate was combined with the above-mentioned Andrographis paniculata L. 1.08-1.10 (60°C), spray-dry to make a dry cream powder, mix with appropriate amount of auxiliary materials, make pellets, and dry to obtain.

Embodiment 2

[0036] Embodiment 2: The three kinds of medicines are cleaned separately, remove impurity, pass the inspection and set aside. Grind Andrographis paniculata and Bitterwood into coarse powder, respectively use 80-85% ethanol as solvent, heat and reflux extract twice, each time for 2 hours, filter the extract, recover the ethanol for later use; decoct Xihuangcao twice with water , each time for 2 hours, combine the decoction, filter, combine the filtrate with the extracts of Andrographis paniculata and Brutaceae, concentrate to a relative density of 1.08-1.10 (60°C), spray dry to make a dry cream powder, and mix with appropriate amount of auxiliary materials , pelletized, dried, and obtained.

Embodiment 3

[0037] Embodiment 3: The three kinds of medicines are cleaned separately, remove impurity, pass the inspection and set aside. Take andrographis paniculata and bitter wood two flavors in the prescription and grind them into coarse powder respectively, use 80-85% ethanol as solvent for Andrographis paniculata, heat and reflux to extract twice, each time for 2 hours, filter the extract, and set aside; bitter wood with 2-5% Hydrochloric acid is used as solvent extraction, the extract is filtered, the pH value is adjusted to 9-10 with NaOH solution, centrifuged, and the precipitate is collected for later use; Xihuangcao is decocted twice with water for 2 hours each time, the decoction is combined, filtered, and concentrated To an appropriate amount, add 5 times the amount of 70% ethanol for alcohol precipitation, stand still, filter, combine with the above-mentioned Andrographis paniculata extract to recover ethanol, concentrate to a relative density of 1.08-1.10 (60 ° C), spray dry...

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Abstract

A Chinese medicine 'Xiaoyan Lidan pill' for treating acute cholecystitis and billary tract inflammation is an improvement to existing relative medicine in the form of tablet. Its preparing process is also disclosed. Its advantages are high curative effect, high release speed, and high biologic utilization rate.

Description

technical field [0001] The invention relates to the technical field of manufacturing technology of Chinese patent medicine pills, in particular to Xiaoyan Lidan Pills and a preparation method thereof. Background technique [0002] Pills are a traditional dosage form. Due to the rapid development of modern science and technology, the continuous upgrading of pharmaceutical machinery and equipment, the advent of new pill-making machines and the wide application of new excipients have given youthful vitality to the ancient dosage form of traditional Chinese medicine pills. It has changed people's traditional prejudice of "black, big and thick" traditional pills, and the pills produced by it have the advantages of fast drug release, high bioavailability, accurate dosage, easy to take, carry, and beautiful appearance. According to my country's relevant drug laws and regulations, changing the dosage form is a new drug research. The original dosage form...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K9/20A61K9/36A61K47/38A61P1/16
Inventor 毛友昌毛小敏
Owner 毛友昌
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