The present invention discloses Yiqingwan bolus of and its preparation. The present invention relates to preparation form innovation on the basis of available granule, and the medicine has the advantages of fast release speed, high bioavailability, less irritation, etc. The medicine has the functions of clearing away heat and toxic material, dispersing blood stasis, cooling blood and arresting bleeding, and has obvious curative effect on virulent fire-evil and blood heat caused fever, red eyes, aphtha, swelling and pain throart, etc.