Sildenafil citrate dripping pill

Abstract

The present invention discloses a kind of medicine composition for treating male's erection dysfunction, and is especially orally taken medicine composition with sildenafil citrate as active component. The present invention aims at providing sildenafil citrate dripping pill with great medicine carrying amount, fast medicine release, quick acting, high bioavailability, less toxic side effect, convenient use and low cost. Sildenafil citrate as effective medicine component is mixed with medicinal carrier as matrix, and mixture is heated to form melt and / or emulsion and / or suspension of sildenafil citrate and matrix, which is dropped in a dripping pill into condensating agent in a dripping pill machine to form via contraction.

Description

technical field [0001] The invention relates to a pharmaceutical composition for treating male erectile dysfunction, in particular to an oral drop pill preparation of the pharmaceutical composition with sildenafil citrate as an active ingredient. Background technique [0002] According to the survey conducted by Professor Zhu Jichuan of the Department of Urology of Peking University People's Hospital, the overall prevalence of male erectile dysfunction (ED) in the three major cities in China is 26.1%; the prevalence of men aged 40 and over is 40.2%. According to this calculation, there are about 26 million ED patients in the urban population of the country. There are more than 300 million adult males in China, and more than half of them have different degrees of sexual dysfunction. Therefore, the total number of adult males suffering from sexual dysfunction should be more than 100 million. These sexual dysfunctions include loss of libido, erectile dysfunction, premature ejac...

AI Technical Summary

Problems solved by technology

Due to the characteristics of conventional tablet preparation technology, such oral preparations have problems such as long dissolution time, low dissolution rate, poor absorption, low bioavailability, and hepatic and intestinal first-pass effects, which affect drug efficacy. full play

At the same time, conventional tablets and capsules will generate relatively large dust during the production process, which will cause certain pollution to the environment.

Furthermore, the amount of these conventional oral preparation auxiliary materials is large, and the relative cost is also high, thereby increasing a certain economic burden to patients.