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Hard capsule for treating vascular headache

A technology for vascular headache and hard capsules, applied in capsule delivery, medical preparations containing active ingredients, nervous system diseases, etc., can solve problems such as unsuitable for long-term and optimal use, and large side effects, and achieve convenient taking and carrying, Fast onset and good stability

Inactive Publication Date: 2005-08-24
张言军
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

At present, most of the drugs for treating migraine are western medicines, which have great side effects and are not suitable for long-term and preferred use; currently, there are many drugs containing Gastrodia elata in traditional Chinese medicine preparations

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0020] Prescription: Chuanxiong 3000g, Bupleurum 300g, Angelica dahurica 150g, Cyperus cyperus 500g

[0021] White peony root 1200g Yu Liren 300g White mustard seed 800g

[0022] Licorice 300g

[0023] Preparation method:

[0024] 1. For the above eight flavors, take Chuanxiong, Rhizoma Cyperi, Bupleurum chinensis, Yu Liren, and Angelica dahurica powder and grind them into coarse powder according to the infiltration method under the liquid extract and extract item, and extract by ethanol percolation. After recovering the ethanol, decompress Concentrate to 293 grams and set aside;

[0025] 2. The above five-flavored medicinal residues and the remaining three flavors of Radix Paeoniae Alba, Glycyrrhizae, and Yu Liren were decocted twice, each time for 2 hours, combined the decoction, concentrated to 3210 grams, added ethanol until the alcohol content reached 75%, precipitated for 48 hours, and took Supernatant, reclaim ethanol to 650 grams;

[0026] 3. Merge the ...

Embodiment 2

[0029] Prescription: Chuanxiong 3000g, Bupleurum 300g, Angelica dahurica 150g, Cyperus 600g

[0030] White peony root 1500g Yu Liren 300g White mustard seed 900g

[0031] Licorice 300g

[0032] Preparation method:

[0033] 4. For the above eight flavors, take Chuanxiong, Rhizoma Cyperi, Bupleurum chinensis, Yu Liren, and Angelica dahurica five-flavored medicinal powder and grind them into coarse powder. According to the percolation method under the extract and extract, use ethanol percolation to extract, recover ethanol, and depressurize Concentrate to 293 grams and set aside;

[0034] 5. The above-mentioned five-flavored medicinal residues and the remaining three flavors of white peony root, licorice, and Yu Liren were decocted twice, each time for 2 hours, combined the decoction, concentrated to 3525 grams, added ethanol until the alcohol content reached 75%, precipitated for 48 hours, and took Supernatant, reclaim ethanol to 706 grams;

[0035] 6. Merge the ...

Embodiment 3

[0038] Determination of content: Determination according to high performance liquid chromatography (Appendix VID of Chinese Pharmacopoeia 2000 edition)

[0039] Chromatographic conditions and system suitability test Octadecylsilane bonded silica gel is used as filler; methanol: water (1:2) is used as mobile phase; detection wavelength is 240nm; theoretical plate is not less than 1000 based on paeoniflorin.

[0040] Preparation of reference substance solution Accurately weigh an appropriate amount of paeoniflorin reference substance, and add methanol to make a reference substance solution containing 120 μg of paeoniflorin per milliliter.

[0041] Preparation of the test solution Take an appropriate amount of this product, grind it finely, take about 1.0g, accurately weigh it, put it in an iodine measuring bottle, add 10ml of methanol precisely, weigh it, and ultrasonically treat it for 45 minutes, take it out, let it cool, and use methanol Make up for lost weight, shake well, a...

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PUM

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Abstract

A Chinese medicine in the form of capsule for treating vascular headache is prepared from 8 Chinese-medicinal materials including Chuan-xiong rhizome, bupleurum root, white peony root, liquorice root, etc. Its preparing process is also disclosed.

Description

technical field [0001] The invention relates to a traditional Chinese medicine hard capsule for treating vascular headache, especially migraine, women's menstrual headache and tension headache. Background technique [0002] Vascular headaches, especially migraines, women's menstrual headaches, and tension headaches, have been diagnosed more than 3,000 years ago. If they are not treated in time, 80% of them will form habitual migraines and form familial hereditary headaches. cause great harm to life. At present, most of the medicines for treating migraine are western medicines, which have large side effects and are not suitable for long-term and preferred use; currently, there are many medicines containing Gastrodia elata in traditional Chinese medicine preparations. Contents of the invention [0003] The purpose of the present invention is to overcome the shortcomings of the prior art, and provide a capsule for treating vascular headache, especially migraine, women's mens...

Claims

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Application Information

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IPC IPC(8): A61K9/48A61P25/04A61P25/06
Inventor 张言军
Owner 张言军
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