Use of cocklebur fruit total glucoside extract in preparing anti inflammation reaction product

An extract and technology of Xanthium, which is applied in the field of traditional Chinese medicine Xanthium glycosides extract and preparation of anti-inflammatory reaction products, can solve the problem that the use of Xanthium extract has not been seen, and the activity of single Xanthium has not been found Issues such as reports on site or active ingredient tracking screening

Inactive Publication Date: 2005-10-26
SECOND MILITARY MEDICAL UNIV OF THE PEOPLES LIBERATION ARMY
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  • Abstract
  • Description
  • Claims
  • Application Information

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Problems solved by technology

[0065] Through literature search, etc., so far, no report has been found on the tracking and screening of the active part or active ingredient of Fructus Xanthium, nor has there been any relevant report on the use of the active part extract of Fructus Xanthium

Method used

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  • Use of cocklebur fruit total glucoside extract in preparing anti inflammation reaction product
  • Use of cocklebur fruit total glucoside extract in preparing anti inflammation reaction product
  • Use of cocklebur fruit total glucoside extract in preparing anti inflammation reaction product

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0185] Embodiment 1, preparation method 1 of cocklebur glycosides extract

[0186] Xanthium 2.5Kg dried medicinal material, reflux extraction with 50 liters of 90% ethanol solution for 2 times, 2 hours each time, combine the two extracts, concentrate under reduced pressure to obtain 350 g of extract, disperse with 2 liters of water, and successively extract with 6 liters Petroleum ether was extracted and degreased three times, and impurities were extracted three times with 6 liters of chloroform and 6 liters of ethyl acetate respectively; the extraction residue was extracted three times with 6 liters of n-butanol, and the extracts were combined and freeze-dried to obtain the total glycosides of Xanthia glycosides. Material 21g.

Embodiment 2

[0187] Embodiment 2, preparation method 2 of cocklebur glycosides extract

[0188] Xanthium 2.5Kg dried medicinal material, ultrasonically extracted 2 times with 50 liters of 70% ethanol solution, 2 hours each time, combined the two extracts, concentrated under reduced pressure to obtain 208 g of extract, dispersed with 2 liters of water, and sequentially extracted in 6 liters Petroleum ether was extracted and degreased three times, and impurities were extracted three times with 6 liters of chloroform and 6 liters of ethyl acetate respectively; the extraction residue was extracted three times with 6 liters of n-butanol, and the extracts were combined and recovered to dryness under reduced pressure to obtain cocklebur Total glycosides extract 17g.

Embodiment 3

[0189] Embodiment 3, preparation method 3 of cocklebur glycosides extract

[0190] 2.5Kg dried medicinal material of Fructus Xanthii, extracted twice by percolation with 50 liters of 75% ethanol solution, 24 hours each time, combined the two extracts, concentrated under reduced pressure to obtain 285g of extract, dispersed with 2 liters of water, and then washed with 6 1 liter of petroleum ether was extracted and degreased three times, respectively extracted three times with 6 liters of chloroform and 6 liters of ethyl acetate to remove impurities; the extraction residue was extracted three times with 6 liters of n-butanol, the combined extracts were recovered to dryness under reduced pressure to obtain Auricularia glycosides extract 19g.

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Abstract

An application of the xanthinoside, which is prepared from xanthium fruit through extracting, separating and purifying, in preparing the medicine for relieving inflammation, relaxing pain and treating rhinitis and nasosinusitis is disclosed.

Description

technical field [0001] The invention relates to the technical fields of medicine, food and beverage, in particular to the use of Chinese medicine extracts, and more specifically to the use of Chinese medicine cocklebur glycosides extracts for preparing anti-inflammatory reaction products. Background technique [0002] (1) Research overview of Fructus Xanthii [0003] 1. Overview of plant resources and applications [0004] Fructus Xanthii (Fructus Xanthii), is the dry ripe fruit with involucre of Xanthium sibirium Patr. Cangzike, etc., are Chinese Pharmacopoeia varieties, which are produced in most parts of China and are extremely rich in resources. Traditional Chinese medicine believes that it has a bitter taste and warm nature, and it belongs to the lung and liver meridians. It has the effects of sweating, dispelling rheumatism, clearing the nose, and relieving pain. It is traditionally used to treat wind-cold headache, runny nose, rubella itching, arthralgia due to dam...

Claims

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Application Information

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Patent Type & Authority Applications(China)
Inventor 秦路平韩婷张巧艳黄宝康郑汉臣
Owner SECOND MILITARY MEDICAL UNIV OF THE PEOPLES LIBERATION ARMY
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