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Effervescent tablets contg. Astragalus root and fructus ligustric lucidi for strengthening the body resistance, and its prepn. art

The technology of Zhenqi Fuzheng and preparation process is applied in the field of Zhenqi Fuzheng effervescent tablet and its preparation, which can solve the problems of inconvenient storage, transportation, inconvenience in carrying and taking, and large volume for patients to take, and saves production time, Stable properties, good effervescent effect

Active Publication Date: 2006-01-25
湖南华宝通制药有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, Zhenqi Fuzheng Granules has a large dosage due to the large amount of auxiliary materials, and the volume is large for patients to take, which is inconvenient to carry and take. It also has high sugar content, slow dissolution, and inconvenient storage and transportation.
In addition, the process mentioned in the original preparation process is simple, and many processes that are conducive to improving quality have not been provided, which is not conducive to the stability of product quality

Method used

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  • Effervescent tablets contg. Astragalus root and fructus ligustric lucidi for strengthening the body resistance, and its prepn. art

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0028] Take 3000g of astragalus and 1500g of Ligustrum lucidum, add water to decoct three times, add 10 times the amount of water for the first time, decoct for 3 hours; add 8 times the amount of water for the second time, decoct for 2 hours; add 8 times the amount of water for the third time, decoct 1 hour; filter, combine the filtrates, concentrate under reduced pressure at 60-65°C and a vacuum of 0.07-0.09Mpa to a relative density of 1.08-1.10 (measured at 60°C), and spray dry to obtain about 945g of dry paste.

[0029] Take 945g of dry paste, add 475g of lactose, 240g of tartaric acid, and 10g of stevia, mix, grind into fine powder, use ethanol to make soft material, then granulate, dry at 60-65°C, granulate, and set aside. Take another 100g of polyethylene glycol-6000 to melt, add 220g of sodium bicarbonate, stir evenly, after cooling, pulverize into fine powder, sieve, mix with the above-mentioned acid granules and 10g of magnesium stearate, press into tablets, and make a...

Embodiment 2

[0031] Take 3000g of astragalus and 1500g of Ligustrum lucidum, add water to decoct three times, add 8 times the amount of water for the first time, decoct for 2 hours; add 6 times the amount of water for the second time, decoct for 1 hour; add 6 times the amount of water for the third time, decoct 0.5 hour; Other steps are with embodiment 1.

Embodiment 3

[0033] Take 3000g of astragalus and 1500g of Ligustrum lucidum, add water to decoct three times, add 12 times the amount of water for the first time, decoct for 3 hours; add 10 times the amount of water for the second time, decoct for 2 hours; add 10 times the amount of water for the third time, decoct 1 hour; filter and combine the filtrates, other steps are the same as in Example 1.

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Abstract

A Chinese medicine in the form of effervescent tablet for strengthening human body resistance is proportionally prepared from the extracts of astragalus root and lucid ligustrum fruit, lactose, rebaudiose, tartaric acid, sodium dicarbonate, poly ethanediol and magnesium stearate. Its preparing process is also disclosed.

Description

technical field [0001] The invention relates to Zhenqi Fuzheng effervescent tablet and a preparation process thereof. Background technique [0002] At present, the similar products produced in China mainly include Zhenqi Fuzheng Granules. Zhenqi Fuzheng Granules are composed of Astragalus membranaceus and Ligustrum lucidum. Astragalus membranaceus is used to invigorate qi and solidify the surface, diuretic and detoxify, drain pus, astringe sores and promote muscle growth. Ligustrum lucidum nourishes the liver and kidney, improves eyesight and black hair. The combination of various medicines nourishes qi and nourishes yin. Zhenqi Fuzheng Granules is a variety recorded in the twentieth volume of "Prescriptions of Traditional Chinese Medicine" by the Ministry of Health of the People's Republic of China; it can improve human immune function, protect bone marrow and adrenal cortex function; it is used for wasting caused by various diseases; The effects of surgery, radiation, a...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/481A61K9/20A61K9/46A61P37/04
Inventor 罗瑞锋邓志方姜新宇
Owner 湖南华宝通制药有限公司
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