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Small golden pellets and preparation method

A technology of gold micro-pills and micro-pills, applied in the field of small gold micro-pills, can solve the problems of large dosage of capsules, large dosage errors, and irregular content particles, so as to improve bioavailability and packaging dosage errors Small size and good clinical compliance

Active Publication Date: 2006-02-01
CHENGDU YONGKANG PHARM CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Due to the large size of paste pills, there is a large error in sub-dosing, which is inconvenient for clinical use, especially for patients with dysphagia
Other dosage forms, such as capsules and tablets, because the original powder is directly used as medicine, the prepared granules are not uniform, the compressed tablets are not standardized, the appearance quality is worse than that of pills, and the fluidity is low. When the capsules are filled, the content particles are irregular. There is a large difference in the amount, the amount of each capsule is about 0.3g, and the dosage of the capsule is large

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0020] Embodiment 1 Preparation of pellets of the present invention

[0021] a. Take the following raw materials by weight:

[0022] 30g of musk, 150g of wood turtle, 150g of aconitum, 150g of sweetgum, 75g of frankincense, 75g of myrrh, 150g of wulingzhi, 75g of angelica, 150g of earthworm, 12g of fragrant ink;

[0023] b. Dry the above-mentioned raw medicinal materials except musk until the water content is below 2.0%, and then pulverize them into ultra-fine powders with a mesh size of 180 or more;

[0024] c. Take the starch and add water, boil it into a paste, and use it as a binder;

[0025] d. Mold removal: manual or mechanical mold removal is adopted, and the diameter of the pellet mold is 0.1 ~ 1.8mm; there are many methods of mold removal, and the powder can be bonded in the coating pot to remove the mold; it can be manually rubbed and cut Demoulding; extruding into strips by machinery, cutting and de-moulding. If the pellet mold is too small, the yield of wrapped ...

Embodiment 2

[0030] Embodiment 2 Preparation of drug pellets of the present invention

[0031] Weigh the raw materials of the following weights: musk 20g, wood turtle 140g, aconitum 140g, sweetgum balm 140g, frankincense 65g, myrrh 65g, wulingzhi 140g, angelica 65g, earthworm 140g, incense ink 6g; The method preparation of example 1.

Embodiment 3

[0032] Embodiment 3 Preparation of drug pellets of the present invention

[0033] Weigh the raw materials with the following weights: 40g of musk, 160g of wood turtle, 160g of aconitum, 160g of sweetgum, 85g of frankincense, 85g of myrrh, 160g of wulingzhi, 85g of angelica, 160g of earthworm, 18g of fragrant ink; Example 1 method preparation.

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Abstract

A Chinese medicine ''Xiaojin micropill'' is prepared from 10 Chinese-medicinal materials including musk, myrrh, Chinese angelica root, earthworm, etc. Its preparing process is also disclosed. Its advantages are short dissolving time and quickly taking its high curative effect.

Description

technical field [0001] The invention provides a small gold micropill, specifically, it is a micropill prepared from the raw material of "Xiaojin pill", which belongs to the field of medicine. Background technique [0002] "Xiaojin Pills", recorded in "Chinese Pharmacopoeia" 2000 edition, the preparation method is: the above ten flavors, except musk, the other nine flavors such as wood turtles are crushed into fine powder, the musk is ground into fine powder, and the above powder is blended and grinded, sieve. Add 25g of starch for every 100g of powder, mix well, and make a thin paste with 5g of starch, pan pills, and dry at low temperature to obtain. Functions and indications: dissipating stagnation and reducing swelling, removing blood stasis and relieving pain. For the initial onset of gangrene, skin color unchanged, swelling and pain, multiple abscesses, goiters, breast rocks, and breast addiction. The commonly used dosage forms are pills, capsules, and tablets. Where...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/714A61K36/736A61K9/16A61P15/14A61P17/00A61P43/00A61K35/24A61K35/55A61K35/62
Inventor 高庆凌许洪
Owner CHENGDU YONGKANG PHARM CO LTD
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