Entecavir dripping pills and method for preparing the same
Patent Information
- Authority / Receiving Office
- CN · China
- Current Assignee / Owner
- FUKANGREN BIO PHARMA
- Publication Date
- 2006-02-15
- Estimated Expiration
- Not applicable · inactive patent
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Abstract
Description
technical field
[0001] The invention relates to a novel pharmaceutical preparation, in particular to entecavir dropping pills for treating hepatitis B and a preparation method thereof. Background technique
[0002] The morbidity and mortality caused by hepatitis B virus ((HBV) in the world is the most serious among liver viruses. According to the statistics of the World Health Organization, there are about 350 million HBV carriers in the world, causing about 100-200 deaths per year At present, there are two kinds of serum vaccines and DNA recombinant vaccines for prophylaxis; and what is commonly used for therapeutic drugs is alpha-interferon, which is not only expensive and difficult to tolerate, but also has low effective rate (only 25%-40 % of patients had remission).
[0003] Entecavir (entecavir) is epoxy hydroxycarbodeoxyguanosine, a deoxyguanosine analogue that can effectively inhibit the replication of hepatitis B virus, and has a strong anti-HBV effect. The chemic...