Nano Chinese medicinal preparation of 'An Gong Niu Huang Wan' and preparation method thereof

Abstract

The invention discloses a nano resurrection Chinese medicinal preparatoin and its preparing process, wherein the preparation is prepared from goldthread root, baikal skullcap root, cape jasmine, curcuma aromatica, cow-bezoar, buffalo horn concentrated powder, musk, pearl powder, cinnabar, orpiment and boneol. The preparation can be made into dose forms including tablets, capsules, granules, and drop pills.

Description

Technical field [0001] The invention belongs to the technical field of traditional Chinese medicine pharmacy, and in particular relates to a nanometer traditional Chinese medicine preparation of Angong Niuhuang and a preparation method thereof. Background technique [0002] The traditional Angong Niuhuang prescription comes from the "Warm Disease Tiaobian" in the Qing Dynasty. It is composed of 11 herbs such as bezoar, buffalo horn concentrated powder, musk, pearl, cinnabar, realgar, coptis, scutellaria, gardenia, turmeric, and borneol. The effect of clearing away heat and detoxification, removing phlegm and resuscitating the mind, mainly treating fever, evil entering the heart, resuscitating the mind, and refreshing the mind. Currently, it is commonly used for various urgent diseases such as cerebrovascular accident, hepatic coma, and uremia. Angong Niuhuang Pills are very cold. Except for realgar, the prescription contains the most cold and cool products in traditional Chi...

AI Technical Summary

Problems solved by technology

The clinical application of Angong Niuhuang Pills has the following disadvantages: 1. It cannot be absorbed quickly, and the first-aid medicine is made into pills, which is not conducive to the rapid dissolution of the active ingredients to exert curative effect; 2. It is difficult to accurately control the dosage, and the medicinal ingredients in Angong Niuhuang Pills Most of them are poisonous, have strong medicinal properties or poor water solubility, so the patient's dosage should be as accurate as possible;

[0003] Niu Rui developed Angong Niuhuang Dispersible Tablets on the basis of traditional Angong Niuhuang Pills ("Research on Angong Niuhuang Dispersible Tablets", Niu Rui, doctoral dissertation of Chengdu University of Traditional Chinese Medicine, 2000): Preparation of cinnabar by jet pulverization , bezoar superfine powder, crushed pearls by ball milling, water extraction of scutellaria baicalensis and coptis, alcohol extraction of gardenia and turmeric, and borneol, musk fine powder, and pharmaceutical excipients to prepare dispersible tablets; this method is only for research and development of dispersible tablets. , the Angong Niuhuang prescription has not been fully studied, resulting in complicated and cumbersome processes, and its pharmacological effects are open to question

[0004] Yang Mengjun's "A Nano-Angong Niuhuang Preparation Drug and Its Preparation Method" used technologies such as microwave extraction, decompression concentration, super-velocity jet technology spray drying to prepare the raw material drug in Angong Niuhuang Pills into nanoscale, but the The utility of the patent is not strong