Nano Chinese medicinal preparation of 'An Gong Niu Huang Wan' and preparation method thereof

A technology of Angong Niuhuang and traditional Chinese medicine preparations, applied in the directions of pharmaceutical formulations, non-central analgesics, antipyretics, etc., can solve the problems of poor water solubility, inability to absorb quickly, and strong medicinal properties, and achieve the effect of preventing loss.

Inactive Publication Date: 2006-12-27
张晴龙
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

The clinical application of Angong Niuhuang Pills has the following disadvantages: 1. It cannot be absorbed quickly, and the first-aid medicine is made into pills, which is not conducive to the rapid dissolution of the active ingredients to exert curative effect; 2. It is difficult to accurately control the dosage, and the medicinal ingredients in Angong Niuhuang Pills Most of them are poisonous, have strong medicinal properties or poor water solubility, so the patient's dosage should be as accurate as possible;
[0003] Niu Rui developed Angong Niuhuang Dispersible Tablets on the basis of traditional Angong Niuhuang Pills ("Research on Angong Niuhuang Dispersible Tablets", Niu Rui, doctoral dissertation of Chengdu University of Traditional Chinese Medicine, 2000): Preparation of cinnabar by jet pulverization , b

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0096] (1) The proportioning by weight of crude drug of the present invention is:

[0097] 20 grams of bezoar, 50 grams of concentrated buffalo horn powder, 6 grams of musk, 12 grams of pearls, 20 grams of cinnabar, 20 grams of realgar, 20 grams of coptis, 20 grams of skullcap, 20 grams of gardenia, 20 grams of turmeric, and 6 grams of borneol.

[0098] (2) Take Coptis chinensis and Scutellaria baicalensis, add water and decoct three times, add 11 times the amount of water for the first time, decoct for 2 hours, add 8 times the amount of water for the second and third times, decoct for 1 hour, combine the decoction, filter, Concentrate the filtrate to obtain the extract; decoction pieces of gardenia and turmeric, pulverize, extract twice with 6 times the amount of 75% ethanol, the first time for 2 hours, the second time for 1 hour, filter, combine the extracts, and the filtrate decompresses to recover ethanol , and concentrated to an extract with a relative density of about 1....

Embodiment 2

[0108] (1) The proportioning by weight of crude drug of the present invention is:

[0109] 20 grams of bezoar, 50 grams of concentrated buffalo horn powder, 6 grams of musk, 12 grams of pearls, 20 grams of cinnabar, 20 grams of realgar, 20 grams of coptis, 20 grams of skullcap, 20 grams of gardenia, 20 grams of turmeric, and 6 grams of borneol.

[0110] (2) Take Coptis chinensis and Scutellaria baicalensis, add water and decoct three times, add 11 times the amount of water for the first time, decoct for 2 hours, add 8 times the amount of water for the second and third times, decoct for 1 hour, combine the decoction, filter, Concentrate the filtrate to obtain the extract; decoction pieces of gardenia and turmeric, pulverize, extract twice with 6 times the amount of 75% ethanol, the first time for 2 hours, the second time for 1 hour, filter, combine the extracts, and the filtrate decompresses to recover ethanol , and concentrated to an extract with a relative density of about 1....

Embodiment 3

[0120] (1) The proportioning by weight of crude drug of the present invention is:

[0121] 20 grams of bezoar, 50 grams of concentrated buffalo horn powder, 6 grams of musk, 12 grams of pearls, 20 grams of cinnabar, 20 grams of realgar, 20 grams of coptis, 20 grams of skullcap, 20 grams of gardenia, 20 grams of turmeric, and 6 grams of borneol.

[0122] (2) Take Coptis chinensis and Scutellaria baicalensis, add water and decoct three times, add 11 times the amount of water for the first time, decoct for 2 hours, add 8 times the amount of water for the second and third times, decoct for 1 hour, combine the decoction, filter, Concentrate the filtrate to obtain the extract; decoction pieces of gardenia and turmeric, pulverize, extract twice with 6 times the amount of 75% ethanol, the first time for 2 hours, the second time for 1 hour, filter, combine the extracts, and the filtrate decompresses to recover ethanol , and concentrated to an extract with a relative density of about 1....

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PUM

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Abstract

The invention discloses a nano resurrection Chinese medicinal preparatoin and its preparing process, wherein the preparation is prepared from goldthread root, baikal skullcap root, cape jasmine, curcuma aromatica, cow-bezoar, buffalo horn concentrated powder, musk, pearl powder, cinnabar, orpiment and boneol. The preparation can be made into dose forms including tablets, capsules, granules, and drop pills.

Description

Technical field [0001] The invention belongs to the technical field of traditional Chinese medicine pharmacy, and in particular relates to a nanometer traditional Chinese medicine preparation of Angong Niuhuang and a preparation method thereof. Background technique [0002] The traditional Angong Niuhuang prescription comes from the "Warm Disease Tiaobian" in the Qing Dynasty. It is composed of 11 herbs such as bezoar, buffalo horn concentrated powder, musk, pearl, cinnabar, realgar, coptis, scutellaria, gardenia, turmeric, and borneol. The effect of clearing away heat and detoxification, removing phlegm and resuscitating the mind, mainly treating fever, evil entering the heart, resuscitating the mind, and refreshing the mind. Currently, it is commonly used for various urgent diseases such as cerebrovascular accident, hepatic coma, and uremia. Angong Niuhuang Pills are very cold. Except for realgar, the prescription contains the most cold and cool products in traditional Chi...

Claims

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Application Information

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IPC IPC(8): A61K36/9066A61K9/16A61K9/20A61K9/48A61P9/10A61P13/12A61P29/02A61P43/00A61K35/56A61K35/55A61K35/413A61K35/32A61K33/36A61K33/28A61K31/045A61K35/618
Inventor 张晴龙
Owner 张晴龙
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