Device and Method for Multi-Phase Radio-Frequency Ablation

Abstract

Multi-phase RF ablation employing a two-dimensional or three-dimensional electrode array produces a multitude of currents paths on the surface of the ablation zone. This results in a uniform lesion with a size defined by the span of the electrode array. An orthogonal electrode catheter array suitable for cardiac ablation is used in conjunction with a two-phase RF power source to produce uniform square-shaped lesions of size 1.2 cm2. Lesions of larger size are created by successive adjacent placement of the square-shaped lesions. A temperature sensor at the electrode tip allows monitoring of ablation temperature and regulation of thereof to minimize the electrode tips from being fouled by coagulum. In another embodiment, an external auxiliary electrode is used in combination with the catheter electrodes. This also produces lesions of greater depth. In yet another embodiment, ablation is performed with a sequence of elementary electrode-electrical configurations.

Description

CROSS REFERENCE TO RELATED APPLICATIONS [0001] This application is a continuation of application Ser. No. 10 / 452,550, filed on May 30, 2003, which in turn is a continuation of application Ser. No. 09 / 922,128, filed on Aug. 3, 2001, now abandoned, which in turn is a continuation of application Ser. No. 09 / 405,733, filed Sep. 24, 1999, now abandoned, which in turn is a continuation-in-part of application Ser. No. 08 / 318,427, filed on Oct. 5, 1994, now U.S. Pat. No. 5,693,078, which in turn is a continuation of application Ser. No. 07 / 726,035, filed on Jul. 5, 1991, now U.S. Pat. No. 5,383,917, which applications are incorporated herein in their entirety by this reference.BACKGROUND OF THE INVENTION [0002] This invention relates to medical devices and, in particular, a multi-electrode catheter and techniques therefor of employing multi-phase radia-frequency power source for ablation of endocardiac tissues. [0003] Cardiac dysrhythmias are commonly known as irregular heart beats or racin...

AI Technical Summary

Benefits of technology

[0019] It is another object of the present invention to increase the size, depth and uniformity of lesions created by RF catheter ablations.

[0020] It is yet another object of the present invention to improve the efficiency of RF catheter ablations.

[0023] In one embodiment, each electrode is supplied with an RF source having a different phase. In this way, potential differences are created between each pair of electrodes in the array, thereby allowing current to flow between each pair of electrodes in the array to form a more uniform heating pattern therein.

[0024] In another embodiment, a simplified power connection configuration provides a phase difference between at least adjacent pairs of electrodes. In this way, potential differences are created between at least adjacent pairs of electrodes in the array, thereby allowing current to flow between each adjacent pair in the array to form a more uniform heating pattern therein.

[0025] One important aspect of the present multi-phase RF scheme is that a conventional external contact backplate is not employed to connect to the ground terminal of the power supply to complete the circuit. Instead, one or more electrodes among the array are connected to the ground terminal of the multi-phase RF power supply. In this way, unlike the conventional schemes, the various RF currents do not flow perpendicular into the tissue between the electrodes and a backplate, but instead, flow parallel to the surface of the tissue between different pairs of electrodes. This arrangement allows various permutations of current paths to form on the tissue's surface, thereby adequately filling the ablation zone spanned by the array.

[0030] The present invention applies multi-phase power to the combination of the electrode array of the catheter and the backplate electrode to effect ablation. This has the advantage of combining the benefit the lateral spread resulted from the use of the electrode array with the depth resulted from the use of the backplate. Typically, power to the backplate and the array of electrodes is phased such that substantial currents flow both lateral and longitudinal to the internal surface under ablation. In this way, a greater volume of ablation zone with good lateral spread and depth is obtained. For example, using the orthogonal electrode catheter array, a lesion 10 mm by 10 mm by 12 mm deep is obtained.

Problems solved by technology

Another common type of cardiac dysrhythmias is ventricular tachycardia (VT), which is a complication of a heart attack or reduction of blood supply to an area of heart muscle, and is a life threatening arrhythmia.

However, some dysrhythmias of the heart are not treatable with drugs.

Both procedures have increased morbidity and mortality and are extremely expensive.

In addition, some patients of advanced age or illness cannot tolerate invasive surgery to excise tachycardia focus which causes dysrhythmias.

Additionally, high voltage techniques have other undesirable side-effects such as barotrauma and the lesions formed could become proarrhythmic.

Therefore, the lesion created by the simple RF technique delivered through a standard electrode catheter may not be large enough to ablate the ventricular tachycardia.

However, this arrangement has been found to be unsatisfactory as there are substantial areas between the electrodes that remain unablated.

Increasing the power only results in charring of the tissues and early fouling of the electrodes by coagulum formation.

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