Bioinformatics systems, apparatuses, and methods executed on a quantum processing platform

Abstract

A system, method and apparatus for executing a bioinformatics analysis on genetic sequence data includes a quantum computing device formed of a set of hardwired quantum logic circuits interconnected by a plurality of superconducting connections to process information represented as a quantum state that is configured as a set of one or more qubits. The hardwired quantum logic circuits may be arranged as a set of processing engines, each processing engine being formed of a subset of the hardwired quantum logic circuits to perform one or more steps in the bioinformatics analysis on the reads of genomic data. Each subset of the hardwired quantum logic circuits may be formed in a wired configuration to perform the one or more steps in the bioinformatics analysis.

Description

CROSS REFERENCES TO RELATED APPLICATIONS

[0001] The present application claims priority to and the benefit of U.S. Provisional Patent Application No. 62 / 462,869, titled “BIOINFORMATICS SYSTEMS, APPARATUSES, AND METHODS EXECUTED ON A QUANTUM PROCESSING PLATFORM,” filed on Feb. 23, 2017, the disclosure of which is incorporated herein by reference in its entirety for all purposes.FIELD OF THE DISCLOSURE

[0002] The subject matter described herein relates to bioinformatics, and more particularly to systems, apparatuses, and methods for implementing bioinformatic protocols, such as performing one or more functions for analyzing genomic data on an integrated circuit, such as on a hardware processing platform.

[0003] Background to the Disclosure

[0004] As described in detail herein, some major computational challenges for high-throughput DNA sequencing analysis is to address the explosive growth in available genomic data, the need for increased accuracy and sensitivity when gathering that data, and...

Examples

Embodiment Construction

[0107]As summarized above, the present disclosure is directed to devices, systems, and methods for employing the same in the performance of one or more genomics and / or bioinformatics protocols, such as a mapping, aligning, sorting, and / or variant call protocol on data generated through a primary processing procedure, such as on genetic sequence data. For instance, in various aspects, the devices, systems, and methods herein provided are configured for performing secondary analysis protocols on genetic data, such as data generated by the sequencing of RNA and / or DNA, e.g., by a Next Gen Sequencer (“NGS”). In particular embodiments, one or more secondary processing pipelines for processing genetic sequence data is provided, such as where the pipelines, and / or individual elements thereof, may be implemented in software, hardware, or a combination thereof in a distributed and / or an optimized fashion so as to deliver superior sensitivity and improved accuracy on a wider range of sequence...

CROSS REFERENCES TO RELATED APPLICATIONS

[0001] The present application claims priority to and the benefit of U.S. Provisional Patent Application No. 62 / 462,869, titled “BIOINFORMATICS SYSTEMS, APPARATUSES, AND METHODS EXECUTED ON A QUANTUM PROCESSING PLATFORM,” filed on Feb. 23, 2017, the disclosure of which is incorporated herein by reference in its entirety for all purposes.FIELD OF THE DISCLOSURE

[0002] The subject matter described herein relates to bioinformatics, and more particularly to systems, apparatuses, and methods for implementing bioinformatic protocols, such as performing one or more functions for analyzing genomic data on an integrated circuit, such as on a hardware processing platform.

[0003] Background to the Disclosure

[0004] As described in detail herein, some major computational challenges for high-throughput DNA sequencing analysis is to address the explosive growth in available genomic data, the need for increased accuracy and sensitivity when gathering that data, and...

Examples

Embodiment Construction

[0107]As summarized above, the present disclosure is directed to devices, systems, and methods for employing the same in the performance of one or more genomics and / or bioinformatics protocols, such as a mapping, aligning, sorting, and / or variant call protocol on data generated through a primary processing procedure, such as on genetic sequence data. For instance, in various aspects, the devices, systems, and methods herein provided are configured for performing secondary analysis protocols on genetic data, such as data generated by the sequencing of RNA and / or DNA, e.g., by a Next Gen Sequencer (“NGS”). In particular embodiments, one or more secondary processing pipelines for processing genetic sequence data is provided, such as where the pipelines, and / or individual elements thereof, may be implemented in software, hardware, or a combination thereof in a distributed and / or an optimized fashion so as to deliver superior sensitivity and improved accuracy on a wider range of sequence...

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