2 results about "Bacteroides dorei" patented technology

The invention discloses application of parabacteroides dieldrii in preparation of a medicine for treating prostatic cancer, and belongs to the field of biological medicine. It is found for the first time that the abundance of parabacteroides dieldrii in intestinal flora of a prostate cancer patient is remarkably reduced, and the parabacteroides dieldrii is selected as potential probiotics for inhibiting growth of prostate cancer tumors. The result of a parabacteroides dieldrii single bacterium colonization experiment shows that the parabacteroides dieldrii and the metabolite gamma-linolenic acid (GLA) thereof can efficiently inhibit the growth of the prostatic cancer tumor, can also improve the condition that the treatment effect of docetaxel on the prostatic cancer is poor due to abuse of clinical antibiotics, and can be prepared into the medicine for treating or assisting in treating the prostatic cancer. The invention provides a new treatment strategy and medicine for the treatment of the prostatic cancer, and also provides a brand new medicine development path and a clinical application scheme for the micro-ecological treatment of the prostatic cancer.

The application discloses application of Bacteroides dorei in preparation of a medicine for improving maternal and offspring outcomes of gestational diabetes mellitus (GDM). The Bacteroides dorei can significantly reduce random blood glucose of a GDM patient, improve glucose tolerance and insulin sensitivity of the GDM patient, relieve intestinal pathological damage caused by the GDM, improve liver steatosis and systemic fat accumulation caused by the GDM, and restore islet structure damage caused by the GDM. The Bacteroides dorei can significantly improve birth outcomes of offspring of the GDM patient, correct abnormal growth and development trajectories of the offspring, improve sugar metabolism levels of the offspring, and improve neurological development behaviors of the offspring of the GDM.